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  1. Against Anti-Fanaticism.Christian Tarsney - manuscript
    Should you be willing to forego any sure good for a tiny probability of a vastly greater good? Fanatics say you should, anti-fanatics say you should not. Anti-fanaticism has great intuitive appeal. But, I argue, these intuitions are untenable, because satisfying them in their full generality is incompatible with three very plausible principles: acyclicity, a minimal dominance principle, and the principle that any outcome can be made better or worse. This argument against anti-fanaticism can be turned into a positive argument (...)
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  2. AI Risk Assessment: A Scenario-Based, Proportional Methodology for the AI Act.Claudio Novelli, Federico Casolari, Antonino Rotolo, Mariarosaria Taddeo & Luciano Floridi - forthcoming - Digital Society.
    The EU Artificial Intelligence Act (AIA) defines four risk categories for AI systems: unacceptable, high, limited, and minimal. However, it lacks a clear methodology for the assessment of these risks in concrete situations. Risks are broadly categorized based on the application areas of AI systems and ambiguous risk factors. This paper suggests a methodology for assessing AI risk magnitudes, focusing on the construction of real-world risk scenarios. To this scope, we propose to integrate the AIA with a framework developed by (...)
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  3. Comparative ethical evaluation of epigenome editing and genome editing in medicine: first steps and future directions.Karla Alex & Eva C. Winkler - 2023 - Journal of Medical Ethics (doi: 10.1136/jme-2022-108888):1-9.
    Targeted modifications of the human epigenome, epigenome editing (EE), are around the corner. For EE, techniques similar to genome editing (GE) techniques are used. While in GE the genetic information is changed by directly modifying DNA, intervening in the epigenome requires modifying the configuration of DNA, for example, how it is folded. This does not come with alterations in the base sequence (‘genetic code’). To date, there is almost no ethical debate about EE, whereas the discussions about GE are voluminous. (...)
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  4. Philosophical aspects of probabilistic seismic hazard analysis (PSHA): a critical review.Luca Zanetti & Daniele Chiffi - 2023 - Natural Hazards:1-20.
    The goal of this paper is to review and critically discuss the philosophical aspects of probabilistic seismic hazard analysis (PSHA). Given that estimates of seismic hazard are typically riddled with uncertainty, diferent epistemic values (related to the pursuit of scientifc knowledge) compete in the selection of seismic hazard models, in a context infuenced by non-epistemic values (related to practical goals and aims) as well. We frst distinguish between the diferent types of uncertainty in PSHA. We claim that epistemic and nonepistemic (...)
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