Scientific Change

It is shown in what sense essential characteristics of formalism, which is normative for exact knowledge, can be found already in Aristotle. It is described how exactness and formalism are pre-conditioned by sensible intuition. The machine character (Turing machine) of a formalism is considered. The general concept of provability leads to an expanding and dynamic understanding of a formalism, with the final source of logical patterns in the "forms of life" (Wittgenstein).

Discussions on the status of definitions of life have long been dominated by a position known as definitional pessimism. Per the definitional pessimist, there is no point in trying to define life. This claim is defended in different ways, but one of the shared assumptions of all definitional pessimists is that our attempts to define life are attempts to provide a list of all necessary and sufficient conditions for something to count as alive. In other words, a definition of life (...) is a strict, descriptive definition. Against this, several pragmatic alternatives have been put forward. On these pragmatic accounts, definitions of life are not strictly, but rather loosely descriptive. Their purpose is not to be true, but to be useful to scientists by guiding scientific practice. More recently, this position has come under attack for not being able to explain how our attempts to define life are connected to scientific progress within the biological sciences. Here, I argue to the contrary by showing how pragmatic definitions of life can be, and in fact are, conducive to scientific progress. Additionally, I show how the pragmatic account of definitions of life can be brought to bear upon our normative discussions involving definitions of life. (shrink)

Scientonomy is the field that aims to develop a descriptive theory of the actual process of scientific change (Barseghyan, 2015). Scientometrics is the field that aims to employ statistical methods to investigate the quantitative features of scientific research, especially the impact of scientific articles and the significance of scientific citations (Leydesdorff & Milojević, 2013). In this paper, we aim to illustrate how to methodologically integrate scientonomy with scientometrics to investigate both qualitative and quantitative changes of a scientific community. We will (...) use a case study to achieve our aim. The case study is about a scientific community studying a physiological phenomenon called heart-rate variability (HRV). Moreover, we will argue that this methodological integration outperforms cases in which researchers only employ the resources from one of the two fields. (shrink)

A volume of papers inspired by the work of George E. Smith on confirmation and evidence in advanced science—from Newton's gravitation theory to the physics of molecules.

Computers are supposed to be smart, yet they frustrate both ordinary users and computer technologists. Why are people frustrated by smart machines? Computers don’t fit people. People think in terms of comparisons, stories, and analogies, and seek feedback, whereas computers are based on a fundamental design that does not fit with analogical and feedback thinking. They impose a binary, an all-or-nothing, approach to everything. Moreover, the social world and institutions that have developed around computer technology hide and reinforce the lack (...) of alignment between computers and people. This book suggests a solution: we do not have to accept the way things are now and work around the bad social and technical design of computers. Rather, it proposes a diverse, distributed, critical discussion of how to design and build both computer technology and its social institutions. (shrink)

Taking the formal analogies between black holes and classical thermodynamics seriously seems to first require that classical thermodynamics applies in relativistic regimes. Yet, by scrutinizing how classical temperature is extended into special relativity, I argue that the concept falls apart. I examine four consilient procedures for establishing the classical temperature: the Carnot process, the thermometer, kinetic theory, and black-body radiation. I argue that their relativistic counterparts demonstrate no such consilience in defining the relativistic temperature. As such, classical temperature doesn’t appear (...) to survive a relativistic extension. I suggest two interpretations for this situation: eliminativism akin to simultaneity, or pluralism akin to rotation. (shrink)

In this paper, the epistemological and conceptual limits of our ability to conceive and reason about future possibilities are analyzed. It is argued that more attention should be paid in futures studies on these epistemological and conceptual limits. Drawing on three cases from philosophy of science, the paper argues that there are deep epistemological and conceptual limits in our ability to conceive and reason about alternatives to the current world. The nature and existence of these limits are far from obvious (...) and become visible only through careful investigation. The cases establish that we often are unable to conceive relevant alternatives; that historical and counterfactual considerations are more limited than has been suggested; and that the present state of affairs reinforces its hegemony through multiple conceptual and epistemological mechanisms. The paper discusses the reasons behind the limits of the conceivability and the consequences that follow from the considerations that make the limits visible. The paper suggests that the epistemological and conceptual limits in our ability to conceive and reason about possible futures should be mapped systematically. The mapping would provide a better understanding of the creative and critical bite of futures studies. (shrink)

Our scientific theories, like our cognitive structures in general, consist of propositions linked by evidential, explanatory, probabilistic, and logical connections. Those theoretical webs ‘impinge on the world at their edges,’ subject to a continuing barrage of incoming evidence. Our credences in the various elements of those structures change in response to that continuing barrage of evidence, as do the perceived connections between them. Here we model scientific theories as Bayesian nets, with credences at nodes and conditional links between them modelled (...) as conditional probabilities. We update those networks, in terms of both credences at nodes and conditional probabilities at links, through a temporal barrage of random incoming evidence. Robust patterns of punctuated equilibrium, suggestive of ‘normal science’ alternating with ‘paradigm shifts,’ emerge prominently in that change dynamics. The suggestion is that at least some of the phenomena at the core of the Kuhnian tradition are predictable in the typical dynamics of scientific theory change captured as Bayesian nets under even a random evidence barrage. (shrink)

I propose an approach that expands philosophical views of scientific change, on the basis of an analysis of contemporary biomedical research and recent developments in the philosophy of scientific change. Focusing on the establishment of the exposome in epidemiology as a case study and the role of data as a context for contrasting views on change, I discuss change at conceptual, methodological, material, and social levels of biomedical epistemology. Available models of change provide key resources to discuss this type of (...) change, but I present the need for an approach that models transfer, alignment, and influence as key processes of change. I develop this as a pragmatic approach to scientific change, where processes might change substantially depending on specific circumstances, thus contributing to and complementing the debate on a crucial epistemological issue. (shrink)

A commissioned 3-volume (800 pages) in-depth introduction to the philosophy of science, peer-reviewed by 11 specialists. (In Hebrew).

In this paper, I defend causal presentism in the historiography of science. In causal presentism, historiography of science studies events, processes and practices that were causally relevant to the development of present science. I argue that causal presentism has three main virtues: First, causal presentism avoids the conceptual problems the historiography of science has recognized in its core. Secondly, causal presentism provides a clear account of what counts as historical explanatory understanding about science. Thirdly, causal presentism enables novel ways to (...) address several conceptual and methodological problems in the historiography of science. The conclusion is that causal presentism is distinctively strong position with respect to the historiography of science. (shrink)

According to John D. Norton's Material Theory of Induction, all reasonable inductive inferences are justified in virtue of background knowledge about local uniformities in nature. These local uniformities indicate that our samples are likely to be representative of our target population in our inductions. However, a variety of critics have noted that there are many circumstances in which induction seems to be reasonable, yet such background knowledge is apparently absent. I call such an absence of circumstances ‘the frontiers of science', (...) where background scientific theories do not provide information about such local uniformities. I argue that the Material Theory of Induction can be reconciled with our intuitions in favour of these inductions. I adapt an attempted justification of induction in general, the Combinatoric Justification of Induction, into a more modest rationalisation at the less foundational level that the critics discuss. Subject to a number of conditions, we can extrapolate from large samples using our knowledge of facts about the minimum proportions of representative subsets of finite sets. I also discuss some of Norton's own criticisms of his theory and argue that he is overly pessimistic. I conclude that Norton's theory at least performs well at the frontiers of science. (shrink)

Sözde-bilim ile ilgili bu tartışmalar uluslararası literatürde yapılıyor olsa da Türkiye’de henüz bu konuların eleştirel olarak ele alındığı söylenemez. Dolayısıyla sözde-bilimlerin eleştirel olarak ele alındığı öğrenme ortamlarının öğrencilerin bilime ve sözde-bilime ilişkin algılarına etkisi üzerine yapılacak araştırmalar konunun daha iyi anlaşılmasını sağlayabilir ve belki de ilerideki program değişiklerinde öğretim programlarında sözde-bilimin yer bulmasının yolunu açabilir.

Jan G. Michel argues that we need a philosophy of scientific discovery. Before turning to the question of what such a philosophy might look like, he addresses two questions: Don’t we have a philosophy of scientific discovery yet? And do we need one at all? To answer the first question, he takes a closer look at history and finds that we have not had a systematic philosophy of scientific discovery worthy of the name for over 150 years. To answer the (...) second question, Michel puts forward three arguments that show the importance of a philosophy of scientific discovery. Briefly, he arrives at the following answers: No, we don’t yet have a philosophy of scientific discovery, and yes, we definitely need one. To remedy this shortcoming, Michel analyzes the concept of discovery, leading him to the insight that scientific discoveries have an underlying structure with certain structural features. Some of these features may be important but not indispensable to scientific discovery processes; these include eureka moments, serendipities, joint discoveries, special science funding, and others. In addition, Michel identifies three indispensable structural features which he examines in detail and which he places in a picture with a certain dynamics according to which the process of making scientific discoveries can be seen as a path, leading us from finding and acceptance to knowledge. (shrink)

Scientific progress depends crucially on scientific discoveries. Yet the topic of scientific discoveries has not been central to debate in the philosophy of science. This book aims to remedy this shortcoming. Based on a broad reading of the term “science” (similar to the German term “Wissenschaft”), the book convenes experts from different disciplines who reflect upon several intertwined questions connected to the topic of making scientific discoveries. -/- Among these questions are the following: What are the preconditions for making scientific (...) discoveries? What is it that we (have to) do when we make discoveries in science? What are the objects of scientific discoveries, how do we name them, and how do scientific names function? Do discoveries in, say, physics and biology, share an underlying structure, or do they differ from each other in crucial ways? Are other fields such as theology and environmental studies loci of scientific discovery? What is the purpose of making scientific discoveries? Explaining nature or reality? Increasing scientific knowledge? Finding new truths? If so, how can we account for instructive blunders and serendipities in science? -/- In the light of the above, the following is an encompassing question of the book: What does it mean to make a discovery in science, and how can scientific discoveries be distinguished from non-scientific discoveries? (shrink)

Bilimi ve bilimsel bilgiyi kültür, değer ve öznel yargılardan izole ederek nesnel bir şekilde ortaya koyabilmeye yönelik hararetli tartışmaların yaşandığı yirminci yüzyıl bilim anlayışının temel gayesi, deney ve gözleme tabi olabilecek fiziki dünyadaki olguları, mantıksal çözümlemeye tabi tutarak birleştirilmiş bilime ulaşmaktır. Bu amaca giden yolda olgulara dayanmayan ve sınanamayan her türlü metafizik öge yok sayılır. Bilimsel bilginin sadece deney ve gözleme tabi olana, diğer bir deyişle olgu verilerine dayandığı iddiasını taşıyan bu düşünce sistemi, özellikle Viyana Çevresi üyeleri tarafından benimsenmiştir. Bu (...) bakımdan Çevre üyelerinin bilimsellik anlayışındaki temel ölçüt olgulara dayanan önermelerin ya da yargıların doğrulanabilmesidir. Bilimsel bilginin sadece olgusal dünyanın gözlemlenmesi ve bu gözlem sonucunda ortaya konulan önermelerin ya da ifadelerin doğrulanmasıyla sağlandığını düşünen Çevre üyelerinin bu savlarındaki amacı bilimi ve onun bilgisini her türlü kültür ve değer alanından uzaklaştırarak metafiziksel unsurlardan arındırılmış nesnel bilgiye ulaşmaktır. Çevre üyelerinin birçoğu bilim alanı içerisinde tartışmaya yol açan meselelerin aslında metafiziksel içerikli ve dolayısıyla bunların görünüşte problemler olduğunu belirterek bu tartışmaların bilimsel bilginin gelişimi önünde bir engel oluşturacağı kanaatindedir (Hızır, 1965, s. 254). Söz gelimi, Carnap’a göre, metafizik ögeler olgusal içeriğe sahip olmadığı ve sınanabilir nitelikte olmadıkları için bilim alanı içerisinde değerlendirilemez. Bu nedenle, metafizik ögeler hem doğrulanması mümkün olmadığı hem de dilin mantıksal dizimine genellikle uymadığı gerekçesiyle anlamsızdır (Öztürk, 2011, s. 155). Bu bakımdan Çevre üyelerine göre, olgulara dayanmayan ve bilimde yanılsamalara yol açan metafizik söylemler bilimden ayıklanmalı ve bilimsel bilgi ancak olgu ve deneye dayanan önermeler üzerinden yürütülmelidir. Öte yandan Çevre düşünürleri mantıksal çözümleme yoluyla olgulara dayanan önermelerin metafiziksel unsurlar içeren önermelerden ayırt edilebileceğini ifade etmiştir. Bu bağlamda metafizik önermeleri, metafizik olmayan önermelerden ayırt edecek ölçütün doğrulanabilirlik olduğunu savunurlar. Çevre üyelerinin bu tutumları bir bakıma bilim ve sözde bilim arasında ayrım yapma ve metafiziği bilimin dışında tutma çabası olarak da değerlendirilebilir (Kabadayı, 2011, s. 39-40). Yirminci yüzyıl bilim anlayışında bilimsel etkinlikte gözlemin ve gözlemi yürüten bilim insanlarının dolaysız öznel duyu verileriyle ilişkili olduğu bu nedenle gözlem verilerinin psikolojizmin etkisinde olduğu fikri ortaya atılır. Başta Neurath olmak üzere dönemin bilim felsefecileri bilimsel bilginin kültür, değer ve psikoloji gibi öznel unsurlardan uzaklaştığı sürece değerli olduğu kanısında olduğu için bu fikre karşı çıkmaktadır (Gillies, 2018, s. 123). Görüldüğü üzere, Çevre üyelerinin temel amacı metafizik önermelerden arındırılmış, olgulara dayanan bir bilime ulaşmaktır. Bu amacın gerçekleşmesine olanak sağlayacak yöntem ise mantıksal çözümlemedir. Bu bağlamda Çevre üyeleri olgulara dayanan ve doğrulanabilen önermelerin, söz dizimi (sentaks) ve anlamsal (semantik) açıdan incelemeye tabi tutulması gerektiğini düşünmektedir (Yardımcı, 2018, s. 13-15). Özellikle Carnap (1935, s. 9-10) doğrulamanın ancak öne sürülen önermenin mantıksal analize tabi tutularak yapılması gerektiğini iddia etmiştir (Irzık, 1962, s. 65). Bununla birlikte, felsefenin işlevi, önermeleri mantıksal analize tabi tutarak yalın hale getirmektir. İşte felsefenin bu yönü Neurath’da bilimin birliği, Carnap’ta ise bilimin sentaksı, yani bilimin mantığı üzerine çalışma anlamına gelir (Hızır, 1965, s. 252). Bilimi, bilim olmayandan ayırma yöntemi olarak kullanılan doğrulama işlemi, teorik bir söylem ve gözlem önermesi arasında yapılan bir işlem olması bakımından mantıksal ve dilsel bir özellik taşır. Buradaki temel sorun ise teorik bir önermenin gözlem önermelerine indirgenebilir nitelikte olması ve gözlem önermelerinin, gözlem ile nasıl ilişki kurduğunu saptamaktır. İşte Viyana Çevresi üyeleri bu ilişkinin protokol önermeleri ile kurulduğu kanaatindedir (Ural, 2012, s. 105-107) çünkü onlara göre; öznelerarası bir bilimin sağlanması için yansız ve anlam karmaşasından arındırılmış bir dil gereklidir (Serin, 2015, s. 55). Bu dil de ancak protokol önermeler aracılığıyla kurulabilir. Bu bağlamda Çevre üyelerinin, metafiziksel ifadeler barındıran önermelerin anlamsızlığı ve bilimleri ortak bir paydada birleştiren fiziksel bir dil oluşturma olmak üzere iki temel hedefinin olduğu söylenebilir (Godfrey-Smith, 2003, s. 25; Salgar, 2012, s. 187). (shrink)

Bilime ve onun bilgisine akademik, politik, ekonomik ve kamusal alanlar olmak üzere birçok alanda diğer bilgi iddialarına kıyasla daha fazla güven duyulmaktadır. Bilime duyulan bu güvenin temelinde büyük ölçüde bilimsel süreçlerin ve yöntemlerin nesnel bir şekilde yürütülmesi ve bu nesnel sürecin bir ürünü olarak bilimsel bilginin tarafsız bilim insanları tarafından ortaya konulduğu düşüncesi yatmaktadır. Bu bakımdan toplum tarafından bilimin tartışılmaz statüsünün ve bilimsel bilgiye verilen değerin belirleyicisi olarak nesnellik özelliği ön plana çıkmaktadır. Bilhassa doğa bilimleri söz konusu olduğunda bilimsel yöntemin (...) olgulara ve dış dünyaya ilişkin nesnel bilgiler sağladığı düşünülmektedir. Bu bakımdan doğa bilimleri, bilimde nesnelliğin paradigmatik örnekleri olarak kabul görmektedir. Beşeri ve sosyal bilimler alanında ise doğa bilimlerine kıyasla nesnellik algısı düşük olmasına rağmen, yöntemlerinin bilimsel yöntemle çalışılmaya uygun olmasından dolayı en azından ilke olarak nesnel olduğu değerlendirilmektedir. Bilimin değerler alanından ziyade olgu alanına ilişkin çalışmalar yürütmesi, bilim insanlarının değerler, anlamlar ve ideallerinden de kendisini izole ederek bilimsel nesnelliği temin edilebileceği konusunda genel bir kavrayışa yol açmaktadır. Bu görüşün önde gelen düşünürü Karl Popper’dır. Popper bilimsel nesnelliğin, olgusal içerikli önermelerin – protokol önermeleri – öznelerarası sınanabilir olması ile temin edilebileceğini ve böylece bilim insanlarının çalışmalarında kültür, değer ve inanç gibi öznel kanılarının bilimsel bilginin temellendirilmesi ve sınanması noktasında kullanılamayacağını ifade etmiştir. Ancak bilimin doğasına yönelik bir soruşturma bilimsel bilginin düşünüldüğü kadar nesnel bir sürece sahip olmadığını, bilim faaliyetini gerçekleştiren bilim insanlarının kişisel çıkarlarının, değerlerinin ve içinde yaşamış oldukları kültürel faktörlerin bilimsel bilginin elde edilmesi sürecinde etkili olabileceğini ortaya koymaktadır. Bu bakımdan bilimin doğasını doğru bir şekilde anlayabilmenin yolu bilimlerde nesnellik ölçütünün sosyolojik ve kültürel unsurlarla yakından ilişkili olduğunu bilmekten geçmektedir. Thomas Kuhn bilimsel değerlendirmelerde değer yargılarının ve kültürel unsurların kaçınılmaz olduğu düşüncesindedir. Kuhn, Popper’ın aksine sosyolojik etmen ve değerleri de işin içerisine katarak bir bilimsel nesnellik değerlendirmesi yapmaktadır. Bu doğrultuda, o bilimde fazlasıyla öznel unsurları vurguladığı eleştirilerine imkân vermeyecek şekilde bilim insanlarının takip etmesi gereken ve tavsiye niteliğinde olan belirli değerler neticesinde bilimsel nesnelliğin ve rasyonalitenin sağlanabileceğini ifade etmektedir. Bu kapsamda çalışmada, bilimin en bilinen özelliği olarak göze çarpan nesnellik kavramı ve düşüncesine yönelik kavramsal bir belirlemenin ardından kültür ve değer gibi sosyolojik unsurların bilimsel objektifliğin ayrılmaz bir parçası olduğu argümanı, Popper ve Kuhn’un çalışmaları göz önünde bulundurularak serimlenecektir. (shrink)

This Introduction provides a rationale for a collection of new paper on Thomas Kuhn. Scholarship on Kuhn has changed dramatically in the last 20 years for numerous reasons. First, scholars studying Kuhn no longer focus narrowly on Structure of Scientific Revolutions. Scholars have been giving careful consideration to Kuhn’s later work. Second, many scholars have been drawing on the vast unpublished resources at the Thomas S. Kuhn Archive at MIT. Third, with the 50th anniversary of the publication of Structure in (...) 2012, there were quite a number of conferences held which led to the publication of a number of volumes reflecting on Kuhn’s impact in philosophy and history of science. These three developments have contributed significantly to our collective understanding of Kuhn and his theories of scientific change and scientific knowledge. Though Kuhn’s position in the philosophy of science can be difficult to gauge, by objective measures Kuhn’s impact is undeniable. Kuhn’s influence outside philosophy of science is also astounding, especially in the social sciences. So it is beyond dispute that Kuhn has had a profound and wide-ranging impact on scholarship. (shrink)

In this paper, I propose a formal framework for modelling the process of testing empirical statements, hypotheses, theories, and research programmes. Unlike the diverse forms of falsificationism, this framework does not require any commitment to classical logic or to any specific system of logic, as it aims to be useful regardless of the logic we presuppose. On this regard, the paper will focus on how this framework applies to two logical contexts: the classical and the paraconsistent contexts. I will show (...) that this framework converges with falsificationism for consistent classical theories, and that it has very interesting consequences for the variety of paraconsistent cases. Concerning the latter cases, what may be called "empirical dialetheism" will be severely undermined as I will show that not even in our quite liberal framework it is possible to reject an "observable contradiction.". (shrink)

Van Fraassen infers the truth of the contextual theory from his observation that it has passed a crucial test. Mizrahi infers the comparative truth of our best theories from his observation that they are more successful than their competitors. Their inferences require, according to the argument from double spaces, the prior belief that it is more likely that their target theories were pulled out from the T-space than from the O-space. The T-space is the logical space of unconceived theories whose (...) appearances agree with their realities; the O-space is the logical space of unconceived theories whose appearances may agree or disagree with their realities. (shrink)

Book review of Paul Feyerabend's "Philosophy of Nature". || Reseña del libro "Philosophy of Nature", escrito por Paul Feyerabend.

Ian Hacking instigated a revolution in 20th century philosophy of science by putting experiments (“interventions”) at the top of a philosophical agenda that historically had focused nearly exclusively on representations (“theories”). In this paper, I focus on a set of conceptual tools Hacking (1992) put forward to understand how laboratory sciences become stable and to explain what such stability meant for the prospects of unity of science and kind discovery in experimental science. I first use Hacking’s tools to understand sources (...) of instability and disunity in rodent behavioral neuroscience. I then use them to understand recent grass-roots collaborative open science initiatives aimed at establishing stability in this research area and tease out some implications for unity of science and kind creation and discovery in cognitive neuroscience. -/- . (shrink)

A. W. F. Edwards is one of the most influential mathematical geneticists in the history of the discipline. One of the last students of R. A. Fisher, Edwards pioneered the statistical analysis of phylogeny in collaboration with L. L. Cavalli-Sforza, and helped establish Fisher's concept of likelihood as a standard of statistical and scientific inference. In this book, edited by philosopher of science Rasmus Grønfeldt Winther, Edwards's key papers are assembled alongside commentaries by leading scientists, discussing Edwards's influence on their (...) own research and on thinking in their field overall. In an extensive interview with Winther, Edwards offers his thoughts on his contributions, their legacy, and the context in which they emerged. This book is a resource both for anyone interested in the history and philosophy of genetics, statistics, and science, and for scientists seeking to develop new algorithmic and statistical methods for understanding the genetic relationships between and among species both extant and extinct. (shrink)

Scientific progress has many facets and can be conceptualized in different ways, for example in terms of problem-solving, of truthlikeness or of growth of knowledge. The main claim of the paper is that the most important prerequisite of scientific progress is the institutionalization of competition and criticism. An institutional framework appropriately channeling competition and criticism is the crucial factor determining the direction and rate of scientific progress, independently on how one might wish to conceptualize scientific progress itself. The main intention (...) is to narrow the divide between traditional philosophy of science and the sociological, economic and political outlook at science that emphasizes the private interests motivating scientists and the subsequent contingent nature of the enterprise. The aim is to show that although science is a social enterprise taking place in historical time and thus is of a contingent nature, it can and in fact does lead to genuine scientific progress - contrary to the claims of certain sociologists of science and other relativists who standardly stress its social nature, but deny its progressive character. I will first deal with the factual issue by way of introducing the main concepts and mechanisms of modern institutional theory and by applying them to the analysis of the cultural phenomenon that we call modern science. I will then turn to the normative issue: what is the appropriate content of the institutional framework, for scientific progress to emerge and be sustained at which level should it be set and by whom? Addressing this problematic is equivalent to conducting a constitutional debate leading to a Constitution of Science. (shrink)

In contemporary human brain mapping, it is commonly assumed that the “mind is what the brain does”. Based on that assumption, task-based imaging studies of the last three decades measured differences in brain activity that are thought to reflect the exercise of human mental capacities (e.g., perception, attention, memory). With the advancement of resting state studies, tractography and graph theory in the last decade, however, it became possible to study human brain connectivity without relying on cognitive tasks or constructs. It (...) therefore is currently an open question whether the assumption that “the mind is what the brain does” is an indispensable working hypothesis in human brain mapping. This paper argues that the hypothesis is, in fact, dispensable. If it is dropped, researchers can “meet the brain on its own terms” by searching for new, more adequate concepts to describe human brain organization. Neuroscientists can establish such concepts by conducting exploratory experiments that do not test particular cognitive hypotheses. The paper provides a systematic account of exploratory neuroscientific research that would allow researchers to form new concepts and formulate general principles of brain connectivity, and to combine connectivity studies with manipulation methods to identify neural entities in the brain. These research strategies would be most fruitful if applied to the mesoscopic scale of neuronal assemblies, since the organizational principles at this scale are currently largely unknown. This could help researchers to link microscopic and macroscopic evidence to provide a more comprehensive understanding of the human brain. The paper concludes by comparing this account of exploratory neuroscientific experiments to recent proposals for large-scale, discovery-based studies of human brain connectivity. (shrink)

Scientists represent their world, grouping and organizing phenomena into classes by means of concepts. Philosophers of science have historically been interested in the nature of these concepts, the criteria that inform their application and the nature of the kinds that the concepts individuate. They also have sought to understand whether and how different systems of classification are related and more recently, how investigative practices shape conceptual development and change. Our aim in this paper is to provide a critical overview of (...) some of the key developments in this philosophical literature and identify some interesting issues it raises about the prospects of the so-called “special sciences”, including psychiatry, psychology, and the mind-brain sciences more generally, to discover natural kinds. (shrink)

Human microbiome research makes causal connections between entire microbial communities and a wide array of traits that range from physiological diseases to psychological states. To evaluate these causal claims, we first examine a well-known single-microbe causal explanation: of Helicobacter pylori causing ulcers. This apparently straightforward causal explanation is not so simple, however. It does not achieve a key explanatory standard in microbiology, of Koch’s postulates, which rely on manipulations of single-microorganism cultures to infer causal relationships to disease. When Koch’s postulates (...) are framed by an interventionist causal framework, it is clearer what the H. pylori explanation achieves and where its explanatory strengths lie. After assessing this ‘simple’, single-microbe case, we apply the interventionist framework to two key areas of microbiome research, in which obesity and mental health states are purportedly explained by microbiomes. Despite the experimental data available, interventionist criteria for explanation show that many of the causal claims generated by microbiome research are weak or misleading. We focus on the stability, specificity and proportionality of proposed microbiome causal explanations, and evaluate how effectively these dimensions of causal explanation are achieved in some promising avenues of research. We suggest some conceptual and explanatory strategies to improve how causal claims about microbiomes are made. (shrink)

Most scientists would hold that science has not established that the cosmos is physically comprehensible – i.e. such that there is some as-yet undiscovered true physical theory of everything that is unified. This is an empirically untestable, or metaphysical thesis. It thus lies beyond the scope of science. Only when physics has formulated a testable unified theory of everything which has been amply corroborated empirically will science be in a position to declare that it has established that the cosmos is (...) physically comprehensible. But this argument presupposes a widely accepted but untenable conception of science which I shall call standard empiricism. According to standard empiricism, in science theories are accepted solely on the basis of evidence. Choice of theory may be influenced for a time by considerations of simplicity, unity, or explanatory capacity, but not in such a way that the universe itself is permanently assumed to be simple, unified or physically comprehensible. In science, no thesis about the universe can be accepted permanently as a part of scientific knowledge independently of evidence. Granted this view, it is clear that science cannot have established that the universe is physically comprehensible. Standard empiricism is, however, as I have indicated, untenable. Any fundamental physical theory, in order to be accepted as a part of theoretical scientific knowledge, must satisfy two criteria. It must be (1) sufficiently empirically successful, and (2) sufficiently unified. Given any accepted theory of physics, endlessly many empirically more successful disunified rivals can always be concocted – disunified because they assert that different dynamical laws govern the diverse phenomena to which the theory applies. These disunified rivals are not considered for a moment in physics, despite their greater empirical success. This persistent rejection of empirically more successful but disunified rival theories means, I argue, that a big, highly problematic, implicit assumption is made by science about the cosmos, to the effect, at least, that the cosmos is such that all seriously disunified theories are false. Once this point is recognized, it becomes clear, I argue, that we need a new conception of science which makes explicit, and so criticizable and improvable the big, influential, and problematic assumption that is at present implicit in physics in the persistent preference for unified theories. This conception of science, which I call aim-oriented empiricism, represents the assumption of physics in the form of a hierarchy of assumptions. As one goes up the hierarchy, the assumptions become less and less substantial, and more and more nearly such that their truth is required for science, or the pursuit of knowledge, to be possible at all. At each level, that assumption is accepted which (a) best accords with the next one up, and (b) has, associated with it the most empirically progressive research programme in physics, or holds out the greatest hope of leading to such an empirically progressive research programme. In this way a framework of relatively insubstantial, unproblematic, fixed assumptions and associated methods is created, high up in the hierarchy, within which much more substantial and problematic assumptions and associated methods, low down in the hierarchy, can be changed, and indeed improved, as scientific knowledge improves. One assumption in this hierarchy of assumptions, I argue, is that the cosmos is physically comprehensible – that is, such that some yet-to-be-discovered unified theory of everything is true. Hence the conclusion: improve our ideas about the nature of science and it becomes apparent that science has already established that the cosmos is physically comprehensible – in so far as science can ever establish anything theoretical. (shrink)

Conceptual analysis as a method of inquiry has long enjoyed popularity in analytic philosophy, including the philosophy of science. In this article I offer a perspective on the ways in which the method of conceptual analysis has been used, and distinguish two broad kinds, namely philosophical and empirical conceptual analysis. In so doing I outline a historical trend in which non-naturalized approaches to conceptual analysis are being replaced by a variety of naturalized approaches. I outline the basic characteristics of these (...) approaches with illustrative examples, arguing that recent developments in the philosophy of science show that in order to achieve a more adequate understanding of scientific endeavour we need to prioritize the naturalized accounts of the method. (shrink)

Much debate about scientific realism concerns the issue of whether it is compatible with theory change over time. Certain forms of ‘selective realism’ have been suggested with this in mind. Here I consider a closely related challenge for realism: that of articulating how a theory should be interpreted at any given time. In a crucial respect the challenges posed by diachronic and synchronic interpretation are the same; in both cases, realists face an apparent dilemma. The thinner their interpretations, the easier (...) realism is to defend, but at the cost of more substantial commitment. The more substantial their interpretations, the more difficult they are to defend. I consider this worry in the context of the Standard Model of particle physics. Examining some selective realist attempts at interpretation, I argue that realism is, in fact, compatible with different commitments on the spectrum of thinner to more substantial, thus mitigating the dilemma. (shrink)

Our paper studies the anatomy of the discovery of the Higgs boson at the Large Hadron Collider and its influence on the broader model landscape of particle physics. We investigate the phases of this discovery, which led to a crucial reconfiguration of the model landscape of elementary particle physics and eventually to a confirmation of the standard model. A keyword search of preprints covering the electroweak symmetry breaking sector of particle physics, along with an examination of physicists own understanding of (...) the discovery as documented in semiannual conferences, has allowed us an empirical investigation of its model dynamics. From our analyses we draw two main philosophical lessons concerning the nature of scientific reasoning in a complex experimental and theoretical environment. For one, from a confirmation standpoint, some SM alternatives could be considered even more confirmed by the Higgs discovery than the SM. Nevertheless, the SM largely remains the commonly accepted account of EWSB. We present criteria for comparing degrees of confirmation and expose some limits of a purely logical approach to understanding the Higgs discovery as a victory for the SM. Second, we understand the persistence of SM alternatives in the face of disfavourable evidence by borrowing the Lakatosian concept of a research programme, where the core idea behind a group of models survives, while other aspects adapt to incoming data. In order to apply this framework to the model landscape of EWSB, we must introduce a new category of research programme, the model-group, and we test its viability using the example of composite Higgs models. (shrink)

Philip Kitcher and I agree that cognitive values are not only intelligible but play an important role in scientific inquiry. We also agree that the importance of authority is critical to understanding the social dimension of such inquiry. We disagree rather deeply concerning what the roles of cognitive goals and the social dimension are.

A constructive interpretation is given of Paul Feyerabend's philosophy'of science as being not really irrationalistic but only pseudo-irrationalistic, and as being in need of an account of how science is distinct and how related to other activities. To this end, Benedetto Croce's philosophy is considered, constructively criticized, and shown to be unexpectedly promising; its valuable element is not the instrumentalistic theory of science officially present in his Logica but the distinctionism-relationism that he practiced everywhere and especially in his literary criticism. (...) A summary is then given of results obtained or expected from an investigation of Galileo Galilei's Dialogue on the Two Chief World Systems carried out in the spirit of such a modified Crocean approach. (shrink)

Die philosophische Diskussion des Begriffes wissenschaftlicher Fortschritt hat sich als schwieriger erwiesen, als es die Philosophen der ersten Hälfte unseres Jahrhunderts sich noch vorgestellt haben. Spätestens seit den Arbeiten Thomas Kuhns ist hierzu eine lebhafte Diskussion entbrannt. Die vorliegende Studie schlägt ein grundsätzliches Neudenken zu diesem Thema vor. Neuere Beiträge, wie der Falsifikationismus, Strukturalismus, Naturalismus und Realismus werden kritisch diskutiert. Es wird dann versucht, der realen Wissenschaftsgeschichte angepasst einen neuen Ausgangspunkt für wissenschaftstheoretisches Denken zu erarbeiten. Eine ausführliche Untersuchung der Geschichte (...) der Kontinentalverschiebung und Plattentektonik bildet den Ausgangspunkt für eine neue Konzeption wissenschaftlicher Erfahrung und Theoriebildung. Der Autor argumentiert für die Position des kritischen Realismus, behauptet die Unabhängigkeit empirischen Fortschritts in der Wissenschaft und ersetzt die Dichotomie Theorie-Erfahrung durch die Trichotomie Theorie-Phänomen-Erfahrung. (shrink)

The ArgumentFranz Borkenau's book, The Transition from Feudal to Modern Thought, serves as background for Grossmann's study. The objective of this book was to trace the sociological origins of the mechanistic categories of modern thought as developed in the philosophy of Descartes and his successors. In the beginning of the seventeenth century, according to Borkenau, mechanistic thinking triumphed over medieval philosophy which emphasized qualitative, not quantitative considerations. This transition from medieval and feudal methods of thought to modern principles is the (...) general theme of Borkenau's book, and is traced to the social changes of this time. According to this work, the essential economic change that marked the transition from medieval to modern times was the destruction of the handicraft system and the organization of labor under one roof and under one management. The roots of the change in thought are to be sought here. With the dismemberment of the handicraft system and the division of labor into relatively unskilled, uniform, and therefore comparable activities, the conception of abstract homogeneous social labor arises. The division of the labor process into simple repeated movements permits a comparison of hours of labor. Calculation with such abstract social unities, according to Borkenau, was the source from which modern mechanistic thinking in general derived its origin.Grossmann, although he considers Borkenau's work a valuable and important contribution, does not believe that the author has achieved his purpose. First of all, he contends that the period that Borkenau describes as the period of the triumph of modern thought over medieval should not be placed at the beginning of the seventeenth century, but in the Renaissance, and that not Descartes and Hobbes but Leonardo da Vinci was the initiator of modern thought. Leonardo's theories, evolved from a study of machines, were the source of the mechanistic categories that culminated in modern thought.If Borkenau's conception as to the historical origin of these categories is incorrect in regard to time, Grossmann claims it follows that it is incorrect also in regard to the social sources to which it is ascribed. In the beginning, the factory system did not involve a division of labor into comparable homogeneous processes, but in general only united skilled handicraftsmen under one roof. The development of machinery, not the calculation with abstract hours of labor, is the immediate source of modern scientific mechanics. This goes back to the Renaissance and has relatively little to do with the original factory system that was finally superseded by the Industrial Revolution.While Borkenau, in tracing the social background of the thought of the period, relies chiefly on the conflicts and strife of political parties, Grossmann regards this as one element only in the formation of the general social situation, which in its entirety and in the interaction of its elements explains the development of modern thought. (shrink)

The landscape of seventeenth-century chemistry is complex, and it is impossible to find in it either a clear-cut distinction between alchemy and chemistry or a sort of simple identification of the two. The seventeenth-century cultural context contained a rich variety of "chemical" discourses with arguments ranging from specific experiments to the justification of the validity of chemistry and its novelty in terms of its extraordinary antiquity. On the basis of an analysis of the works by O. Borch, J.J. Glauber, and (...) J. J. Becher, this paper tries to demonstrate that a historical reconstruction of "chemistry" must consider these different levels of the chemical debate. Only then will it be possible to appreciate the outstanding role played by G.E. Stahl in founding modern chemistry. The paper argues in favor of a contextualization of the historical research on seventeenth-century chemistry. (shrink)

Drawing on a half century of scholarship, of Polish studies of Copernicus and Cracow University, and of Copernicus's sources, this book offers a comprehensive re-evaluation of Copernicus's achievement, and explains his commitment to the ...