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  1. added 2020-04-28
    Human Embryos, Human Beings: A Scientific and Philosophical Approach. [REVIEW]Bruce Philip Blackshaw - 2020 - The New Bioethics 1:1-3.
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  2. added 2020-02-05
    Crucial Stem Cell Experiments? Stem Cells, Uncertainty, and Single-Cell Experiments.Melinda Bonnie Fagan - 2015 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 30 (2):183-205.
    I have previously argued that stem cell experiments cannot demonstrate that a single cell is a stem cell. Laplane and others dispute this claim, citing experiments that identify stem cells at the singlecell level. This paper rebuts the counterexample, arguing that the alleged ‘crucial stem cell experiments’ do not measure self-renewal for a single cell, do not establish a single cell’s differentiation potential, and, if interpreted as providing results about single cells, fall into epistemic circularity. I then discuss the source (...)
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  3. added 2020-02-03
    Effect of Radiation on the Mouse Stem Cell Compartment in Vivo.Clifford W. Curney - 1963 - Perspectives in Biology and Medicine 6 (2):233-245.
  4. added 2019-12-26
    Defining Life From Death: Problems with the Somatic Integration Definition of Life.Bruce P. Blackshaw & Daniel Rodger - 2020 - Bioethics:1-5.
    To determine when the life of a human organism begins, Mark T. Brown has developed the somatic integration definition of life. Derived from diagnostic criteria for human death, Brown’s account requires the presence of a life‐regulation internal control system for an entity to be considered a living organism. According to Brown, the earliest point at which a developing human could satisfy this requirement is at the beginning of the fetal stage, and so the embryo is not regarded as a living (...)
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  5. added 2019-12-03
    Review of Peoples' Science: Bodies and Rights on the Stem Cell Frontier. [REVIEW]Joan H. Robinson - 2016 - Spontaneous Generations 8 (1):112-114.
  6. added 2019-11-21
    Avoiding the Potentiality Trap: Thinking About the Moral Status of Synthetic Embryos.Monika Piotrowska - forthcoming - Monash Bioethics Review.
    Research ethics committees must sometimes deliberate about objects that do not fit nicely into any existing category. This is currently the case with the “gastruloid,” which is a self-assembling blob of cells that resembles a human embryo. The resemblance makes it tempting to group it with other members of that kind, and thus to ask whether gastruloids really are embryos. But fitting an ambiguous object into an existing category with well-worn pathways in research ethics, like the embryo, is only a (...)
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  7. added 2019-08-13
    Ethics Watch: The Threatened Trade in Human Ova.Donna Dickenson - 2004 - Nature Reviews Genetics 5 (3):167.
    It is well known that there is a shortage of human ova for in vitro fertilization (IVF) purposes, but little attention has been paid to the way in which the demand for ova in stem-cell technologies is likely to exacerbate that shortfall and create a trade in human eggs. Because the 'Dolly' technology relies on enucleated ova in large quantities, allowing for considerable wastage, there is a serious threat that commercial and research demands for human eggs will grow exponentially from (...)
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  8. added 2019-06-27
    Thinking Critically About Abortion: Why Most Abortions Aren’T Wrong & Why All Abortions Should Be Legal.Nathan Nobis & Kristina Grob - 2019 - Atlanta, GA: Open Philosophy Press.
    This book introduces readers to the many arguments and controversies concerning abortion. While it argues for ethical and legal positions on the issues, it focuses on how to think about the issues, not just what to think about them. It is an ideal resource to improve your understanding of what people think, why they think that and whether their (and your) arguments are good or bad, and why. It's ideal for classroom use, discussion groups, organizational learning, and personal reading. -/- (...)
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  9. added 2019-06-20
    Who Owns Embryonic and Fetal Tissue?Donna Dickenson - 2002 - In Ethical Issues in Maternal-Fetal Medicine. Cambridge: Cambridge University Press. pp. 233-244.
    Until very recently the question of who owns embryonic or fetal tissue was of limited importance to clinicians, but advances in stem cell research have made such tissue commercially valuable. This chapter examines the legal and ethical basis of claims to property in embryonic or fetal tissue, taking a critical stance.
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  10. added 2019-06-19
    The Threatened Trade in Human Ova.Donna Dickenson - 2004 - Nature Reviews Genetics 5 (3):157.
    It is well known that there is a shortage of human ova for in vitro fertilization (IVF) purposes, but little attention has been paid to the way in which the demand for ova in stem-cell technologies is likely to exacerbate that shortfall and create a trade in human eggs. Because the 'Dolly' technology relies on enucleated ova in large quantities, allowing for considerable wastage, there is a serious threat that commercial and research demands for human eggs will grow exponentially from (...)
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  11. added 2019-06-18
    Good Science and Good Ethics: Why We Should Discourage Payment for Eggs in Stem Cell Researchonation.Donna Dickenson - 2009 - Nature Reviews Genetics 10 (11):743.
    Payment for eggs used in stem cell research puts women at unacceptable risk and encourages exploitative commodification of the female body. Thanks to the development of induced pluripotent stem cells, however, we no longer face a choice between good science and good ethics.
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  12. added 2019-06-18
    The Lady Vanishes: What’s Missing From the Stem Cell Debate.Donna L. Dickenson - 2006 - Journal of Bioethical Inquiry 3 (1):43-54.
    Most opponents of somatic cell nuclear transfer and embryonic stem cell technologies base their arguments on the twin assertions that the embryo is either a human being or a potential human being, and that it is wrong to destroy a human being or potential human being in order to produce stem cell lines. Proponents’ justifications of stem cell research are more varied, but not enough to escape the charge of obsession with the status of the embryo. What unites the two (...)
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  13. added 2019-06-17
    Bioethics: All That Matters.Donna Dickenson - 2012 - London: Hodder.
    Should we do whatever science lets us do? This short introduction in the 'All That Matters' series shows how developments in biotechnology, such as genetics, stem cell research and artificial reproduction, arouse both our greatest hopes and our greatest fears. Many people invest the new biotechnology with all the aspirations and faith once accorded to religious salvation. But does everyone benefit equally from scientific progress? This book argues that although we've entered new scientific territory, there is no need to jettison (...)
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  14. added 2019-06-14
    Disappearing Women, Vanishing Ladies and Property in Embryos.Donna Dickenson - 2017 - International Journal of Law and the Biosciences 4:1-6.
    Guidelines on embryo storage prioritise 'respect for the embryo' above the wishes of the women whose labour and tissue have gone into creating the embryo in the first place, effectively making women and the female body disappear. In this article I draw a parallel between this phenomenon relating to embryo storage and other instances of a similar phenomenon that I have called 'the lady vanishes', particularly in stem cell and 'mitochondrial transfer' research. I suggest that a modified property regime could (...)
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  15. added 2019-06-06
    Stem Cell Regulation in Mexico: Current Debates and Future Challenges.María de Jesús Medina Arellano - 2011 - Law and Ethics of Human Rights 5 (1):Article 2.
    The closely related debates concerning abortion, the protection of the embryo and stem cell science have captured the legislative agenda in Mexico in recent years. This paper examines some contemporary debates related to stem cell science and the legal and political action that has followed in the wake of the latest Supreme Court judgment on abortion, which debates are directly linked to the degrees of protection of the embryo stipulated in the Mexican Constitution. While some Mexican states have opted to (...)
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  16. added 2019-06-06
    Biotechnotheology and Demythologization of Stem‐Cell Research.Tadej Strehovec - 2009 - Zygon 44 (4):797-806.
    . Biotechnology deals not only with new types of therapies for preventing and curing diseases but also with the creation of new technologies for the production of human flesh. Its ultimate aim is to create a new human body, a new person. Biotechnology wears the cloak not only of a new scientific paradigm but also of a kind of messianic religion. To develop new therapies, to destroy illnesses, to transform the human body into a nonmortal one—these are some of the (...)
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  17. added 2019-06-06
    Research Ethics: Embryonic Stem Cell Research is Not Dehumanising Us.L. Klostergaard - 2009 - Journal of Medical Ethics 35 (12):774-777.
    It is not possible on naturalistic grounds to argue either for or against an entity such as the human embryo having full moral status and deserving our fullest moral attention. In addition, it is difficult to see the point of asserting this moral status. Instead of citing nature as the grounds for demarcating moral status, perhaps it would be better to look at the decisions and activities that demarcate nature and establish the nature–culture gap. Our decisions and activities are expressions (...)
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  18. added 2019-06-06
    The Contribution of the Protestant1 Church in Germany to the Pluralist Discourse in Bioethics: The Case of Stem Cell Research: Articles.Ralph Charbonnier - 2008 - Christian Bioethics 14 (1):95-107.
    Christian contributions to the public discourse on bioethics come from individual Christians, from Christian churches, and from academic theology. All contributors must frame their arguments in such a way as to account for the pluralism of worldviews in contemporary Germany. For this purpose, they must take issue with certain hermeneutical and discourse theoretical considerations. That is to say, in order for their contributions to remain normatively authentic in a Christian and Protestant sense, these must relate to Scripture and to Protestantism's (...)
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  19. added 2019-06-06
    Human Stem Cell Research: NIH Releases Draft Guidelines for Comment.Susan Lee - 2000 - Journal of Law, Medicine and Ethics 28 (1):81-83.
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  20. added 2019-06-05
    Border Disputes Across Bodies: Exploitation in Trafficking for Prostitution and Egg Sale for Stem Cell Research.Heather Widdows - 2009 - International Journal of Feminist Approaches to Bioethics 2 (1):5-24.
    In recent decades, debates about exploitation have tended to be subsumed by debates about choice and autonomy. This phenomenon has affected international feminism adversely, creating polarized debates over such issues as prostitution. Equally grave is the more recent tendency, even among some feminists, to assume that a woman's free choice to accept payment for egg "donation" in somatic cell nuclear transfer stem cell research absolves researchers of any charge of exploitation or abuse of research subjects. This paper suggests that much (...)
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  21. added 2019-06-05
    Stem Cells, Biotechnology, and Human Rights: Implications for a Posthuman Future.Paul Lauritzen - 2005 - Hastings Center Report 35 (2):25.
    : Successful stem cell therapies might change the natural contours of human life. If that happened, it would unsettle our ethical commitments and encourage us to see the entire natural world merely as material to be manipulated.
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  22. added 2019-05-30
    In Dubio Pro Embryone? Schwierigkeiten Eines Vorsichtsarguments Gegen Embryonale StammzellenforschungIn Dubio Pro Embryone? Problems for a Precautionary Argument Against Embryonic Stem Cell Research.Hans-Jürgen Link - 2013 - Ethik in der Medizin 25 (2):129-142.
    ZusammenfassungIn der Debatte um die embryonale Stammzellenforschung führen die Verfechter der Würde des Embryos gerne eine Gemeinsamkeit von Embryonen und reversibel Komatösen an: Beide sind bloß potentiell Personen. Wenn aber Komatösen fraglos personale Würde zukommt, weshalb sollte man sie Embryonen absprechen? In ihrem AufsatzIn dubio pro embryone kombinieren G. Damschen und D. Schönecker diese Analogie mit einem Vorsichtsargument: Weil die Analogie zumindest gute Gründe für die Annahme biete, Embryonen komme eine menschliche Würde zu, sei angesichts der Schwere des möglichen Unrechts (...)
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  23. added 2019-01-10
    Die Würde Menschlicher Embryonen. Zur Moralischen Relevanz von Potentialität Und Numerischer Identität.Gregor Damschen & Dieter Schönecker - 2003 - Internationale Zeitschrift für Philosophie (2):44-69.
    The dignity of human embryos. On the moral relevance of potentiality and numerical identity. -.
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  24. added 2019-01-10
    In Dubio Pro Embryone. Neue Argumente Zum Moralischen Status Menschlicher Embryonen.Gregor Damschen & Dieter Schönecker - 2003 - In Gregor Damschen & Dieter Schönecker (eds.), Der moralische Status menschlicher Embryonen. Pro und contra Spezies-, Kontinuums-, Identitäts- und Potentiali­tätsargument. Berlin & New York: de Gruyter. pp. 187-267.
    When in doubt, for the embryo. New arguments on the moral status of human embryos. - In the first part of our essay we distinguish the philosophical from the legal and political level of the embryo debate and describe our indirect justification strategy. It consists in renouncing a determination of the dignity-giving φ-properties and instead starting from premises that are undoubted by all discussion partners. In the second part we reconstruct and criticize the species, continuum, identity and potentiality arguments. The (...)
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  25. added 2019-01-10
    Zukünftig Φ. Über Ein Subjektivistisches Gedankenexperiment in der Embryo­Nendebatte.Gregor Damschen & Dieter Schönecker - 2003 - Jahrbuch für Wissenschaft Und Ethik 8:67-93.
    In future φ. On a subjectivist thought experiment in the embryo debate. -.
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  26. added 2018-12-12
    Der moralische Status menschlicher Embryonen. Pro und contra Spezies-, Kontinuums-, Identitäts- und Potentiali­tätsargument.Gregor Damschen & Dieter Schönecker (eds.) - 2003 - Berlin & New York: de Gruyter.
    In the debate about the moral status of human embryos, it is not always clear which arguments are actually disputed. This book offers students and researchers, but also laypersons interested in the current debate, the opportunity to inform themselves about the current state of discussion and to learn about the most important arguments in a clear and concise form. These arguments are as follows: Since embryos as members of the species homo sapiens sapiens are human beings, they possess dignity (species (...)
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  27. added 2018-09-12
    Vulnerable Embryos: A Critical Analysis of Twinning, Rescue, and Natural-Loss Arguments.Stephen Napier - 2010 - American Catholic Philosophical Quarterly 84 (4):781-810.
    Contemporary philosophical discussion on human embryonic stem cell research has focused primarily on the metaphysical and meta-ethical issues suchresearch raises. Though these discussions are interesting, largely ignored are arguments rooted in the secular research ethics tradition already informing humansubject research. This tradition countenances the notion of vulnerability and that vulnerable human subjects ought to be protected from research-related harms. This is the basic idea behind the argument from vulnerability, and it enjoys prima facie plausibility. This articlepresents the vulnerability argument and (...)
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  28. added 2018-07-23
    Cancer Stem Cells Modulate Patterns and Processes of Evolution in Cancers.Lucie Laplane - 2018 - Biology and Philosophy 33 (3-4):18.
    The clonal evolution model and the cancer stem cell model are two independent models of cancers, yet recent data shows intersections between the two models. This article explores the impacts of the CSC model on the CE model. I show that CSC restriction, which depends on CSC frequency in cancer cell populations and on the probability of dedifferentiation of cancer non-stem cells into CSCs, can favor or impede some patterns of evolution and some processes of evolution. Taking CSC restriction into (...)
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  29. added 2018-07-23
    Cancer Stem Cells: Philosophy and Therapies.Lucie Laplane - 2016 - Cambridge (Massachusetts): Harvard University Press.
  30. added 2018-07-23
    Stem Cell Epistemological Issues. Chapter in Charbord P and Durand C (Eds) Stem Cell Biology and Regenerative Medicine.Lucie Laplane - 2015 - River Publishers.
    This chapter brings a philosophical perspective to the concept of stem cell. Three general questions both clarify the concept of stem cell and emphasize its ambiguities: (1) How should we define stem cells? (2) What makes them different from non-stem cells? (3) What is their ontology? (i.e. what kind of property is “stemness”?) Following this last question, the Chapter distinguishes four conceptions of stem cells and highlights their respective consequences for the cancer stem cell theory. Determining what kind of property (...)
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  31. added 2018-07-23
    Reprogramming and Stemness.Lucie Laplane - 2015 - Perspectives in Biology and Medicine 58 (2):229-246.
    Reprogramming technologies show that cellular identity can be reprogrammed, challenging the classical conception of cell differentiation as an irreversible process. If non-stem cells can be reprogrammed into stem cells, then what is it to be a stem cell, and what kind of property is stemness? This article addresses this question both philosophically and biologically, states the different possibilities, and illustrates their potential consequences for science with the example of anti-cancer therapies.
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  32. added 2018-03-15
    Stem Cell Research and Same Sex Reproduction.Thomas Douglas, Catherine Harding, Hannah Bourne & Julian Savulescu - 2012 - In Muireann Quigley, Sarah Chan & John Harris (eds.), Stem Cells: New Frontiers in Science and Ethics. World Scientific.
    Recent advances in stem cell research suggest that in the future it may be possible to create eggs and sperm from human stem cells through a process that we term in vitro gametogenesis (IVG). IVG would allow treatment of some currently untreatable forms of infertility. It may also allow same-sex couples to have genetically-related children. For example, cells taken from one man could potentially be used to create an egg, which could then be fertilised using naturally produced sperm from another (...)
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  33. added 2018-02-17
    Stem Cell Research on Embryonic Persons Is Just.Aaron Rizzieri - 2012 - Journal of Bioethical Inquiry 9 (2):195-203.
    Abstract I argue that embryonic stem cell research is fair to the embryo, even on the assumption that the embryo has attained full personhood and an attendant right to life at conception. This is because the only feasible alternatives open to the embryo are to exist briefly in an unconscious state and be killed or to not exist at all. Hence, one is neither depriving the embryo of an enduring life it would otherwise have had nor is one causing the (...)
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  34. added 2017-09-04
    Embryos, The Principle of Proportionality, and the Shaky Ground of Moral Respect.Jonathan Pugh - 2014 - Bioethics 28 (8):420-426.
    The debate concerning the moral permissibility of using human embryos in human embryonic stem cell (hESC) research has long centred on the question of the embryo's supposed right to life. However, in focussing only on this question, many opponents to hESC research have escaped rigorous scrutiny by making vague and unfounded appeals to the concept of moral respect in order to justify their opposition to certain hESC practices. In this paper, I offer a critical analysis of the concept of moral (...)
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  35. added 2017-09-04
    Concerns About Eroding the Ethical Barrier to in Vitro Eugenics: Lessons From the hESC Debate.Jonathan Pugh - 2014 - Journal of Medical Ethics 40 (11):737-738.
    In his discussion of in vitrogametogenesis, Rob Sparrow claims that an ethical barrier to development of this technology is that many jurisdictions currently prohibit the practice of creating embryos solely for the purpose of research. However, he suggests that this ethical barrier will soon be eroded, in view of the fact that in vitro gametogenesis could serve as a powerful new technology to overcome infertility. In this commentary, I argue that Sparrow is being overly optimistic in his analysis here. I (...)
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  36. added 2017-08-07
    Stem Cell Lineages: Between Cell and Organism.Melinda Bonnie Fagan - 2017 - Philosophy, Theory, and Practice in Biology 9 (6).
    Ontologies of living things are increasingly grounded on the concepts and practices of current life science. Biological development is a process, undergone by living things, which begins with a single cell and (in an important class of cases) ends with formation of a multicellular organism. The process of development is thus prima facie central for ideas about biological individuality and organismality. However, recent accounts of these concepts do not engage developmental biology. This paper aims to fill the gap, proposing the (...)
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  37. added 2017-01-27
    Ethical Analysis of the Embryonic Stem Cell Controversy.Francisco Lara - 2012 - Eubios Journal of Asian and International Bioethics 22 (6):226-235.
    Medical research on human embryo stem cells has provoked a considerable amount of moral controversy. In this paper, the author critically analyses the arguments in this debate. A theory of moral status that coherently and plausibly advocates the use of embryonic stem cells in therapeutic research is also outlined.
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  38. added 2017-01-27
    Monotheistic Religions' Perspectives on Embryonic Stem Cell Research.Mansooreh Saniei & Raymond de Vries - 2008 - Eubios Journal of Asian and International Bioethics 18 (2):45-50.
    The controversy about research on human embryonic stem cells raises many fundamental ethical and religious questions, especially about the sanctity of lifeand the Divine mandate of human dominion over nature. This paper reviews the different perspectives of three monotheistic religions on the use of embryo for stem cell research. Looking at the religious perspectives, it shows us that Islam and Judaism support most forms of stem cell research. Both of them express their beliefs on when life begins or what the (...)
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  39. added 2017-01-27
    Stem Cell Research: Science, Ethics and the Popular Media.Karori Mbũgua - 2007 - Eubios Journal of Asian and International Bioethics 17 (1):5-10.
    Few advances in the history of science and technology have generated as much ethical controversy and captured as much public attention as research on human stem cells. This paper distinguishes two parallel research programs involving stems cells: embryonic and adult stem cell research programs, then surveys the ethical arguments advanced for and against human embryonic stem cell research. The popular media has tended to exaggerate the therapeutic potential of embryonic stem cells. Adult stem cell therapies are already available for different (...)
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  40. added 2017-01-25
    Procedural Ethics and the European Stem Cell Debate.Benjamin J. Capps - 2006 - Jahrbuch für Wissenschaft Und Ethik 11 (1):41-66.
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  41. added 2017-01-23
    The Harm That Religion Does.Peter Singer - 2004 - Free Inquiry 24.
    Ever since August 2001, when President Bush announced his shaky compromise policy on federal funding for research on stem cells, American scientists have been charging that the policy severely impedes progress in this promising new area. Bush's policy allowed federal funding only for research using stem cell lines that were in existence on the date of his speech. Thus, he maintained, such funding would not encourage anyone to destroy human embryos to obtain stem cells, because if they did so, the (...)
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  42. added 2017-01-17
    Science and Politics in the Regulation of Human Embryonic Stem-Cell Research in Brazil.Maya Mitre & Bruno P. W. Reis - 2015 - Social Science Information 54 (1):3-22.
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  43. added 2017-01-17
    Altered Nuclear Transfer as a Morally Acceptable Means for the Procurement of Human Embryonic Stem Cells.William B. Hurlbut - 2005 - The National Catholic Bioethics Quarterly 5 (1):145-151.
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  44. added 2017-01-17
    Remarks to President Bush on Stem Cell Research.John Paul - 2001 - The National Catholic Bioethics Quarterly 1 (4):617-618.
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  45. added 2017-01-17
    Address on Public Funding of Stem Cell Research.George W. Bush - 2001 - The National Catholic Bioethics Quarterly 1 (4):619-622.
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  46. added 2017-01-15
    Thought Experiments, the Reliability of Intuitions, and Human Embryonic Stem Cell Research.Stephen Napier - 2016 - International Philosophical Quarterly 56 (1):77-98.
    It is common in bioethical discussion to present thought experiments or cases in order to construct an argument. Some thought experiments are quite illuminating, and ethical theorizing will often appeal at some point to one’s intuitions. But there are cases in which thought experiments are useless or do not contribute to the argument. This article considers cases presented in the context of stem cell research that are destructive of human embryos. I argue that certain popular cases that are meant to (...)
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  47. added 2017-01-15
    Human Embryonic Stem Cell Research: Middle-Ground Positions and Moral Compromise.Angeliki Kerasidou - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 57:167-169.
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  48. added 2017-01-15
    Human Tissue Legislation in South Africa: Focus on Stem Cell Research and Therapy.Michael Sean Pepper & M. Nőthling Slabbert - 2015 - South African Journal of Bioethics and Law 8 (2):4.
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  49. added 2017-01-15
    Embryo Stem Cell Research: Ten Years of Controversy.John A. Robertson - 2010 - Journal of Law, Medicine and Ethics 38 (2):191-203.
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  50. added 2017-01-15
    WARF's Stem Cell Patents and Tensions Between Public and Private Sector Approaches to Research.John M. Golden - 2010 - Journal of Law, Medicine and Ethics 38 (2):314-331.
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