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Ethical dilemmas in neurodegenerative disease: respecting patients at the twlight of agency

In Judy Illes (ed.), Neuroethics: Defining the Issues in Theory, Practice and Policy. Oxford University Press (2005)

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  1. The Principle of Autonomy and Behavioural Variant Frontotemporal Dementia.Veljko Dubljević - 2020 - Journal of Bioethical Inquiry 17 (2):271-282.
    Behavioural variant frontotemporal dementia is characterized by an absence of obvious cognitive impairment and presence of symptoms such as disinhibition, social inappropriateness, personality changes, hyper-sexuality, and hyper-orality. Affected individuals do not feel concerned enough about their actions to be deterred from violating social norms, and their antisocial behaviours are most likely caused by the neurodegenerative processes in the frontal and anterior temporal lobes. BvFTD patients present a challenge for the traditional notion of autonomy and the medical and criminal justice systems. (...)
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  • Stimulating Brains, Altering Minds.W. Glannon - 2009 - Journal of Medical Ethics 35 (5):289-292.
    Deep-brain stimulation has been used to treat advanced Parkinson disease and other neurological and psychiatric disorders that have not responded to other treatments. While deep-brain stimulation can modulate overactive or underactive regions of the brain and thereby improve motor function, it can also cause changes in a patient’s thought and personality. This paper discusses the trade-offs between the physiological benefit of this technique and the potential psychological harm.
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