In this paper we argue, from an inferential approach, that the inferential role played by a model, during modeling practice, is independent of the notion of representation engaged with the chosen modeling approach. Indeed, we believe that the notion of surrogative reasoning is neither subsidiary nor founded on the notion of representation and that it will only find its foundations in logic itself. Neither the notion of representation is an inferential notion nor FIM is a type of representation-based thinking.

This paper aims to propose an inferential and dynamic approach to understanding with models in biology. Understanding plays a central role in the practice of modeling. From its links with the other two central elements of scientific research, experimentation, and explanation, we show its epistemic relevance to the case of explanation in biology. Furthermore, by including the notion of understanding, we propose a non-referentialist perspective on scientific models, which is determined by their use.