In the present article, we discuss the specificity of the object of the history of science as an autonomous and interdisciplinary field of studies by nature and origin, placed at the interface of history, epistemology and science, and focus on some key historiographical views. Within this context, Georges Canguilhem stands out for contributions such as calling the attention to the relevance of epistemology in science history research and the discontinuity-continuity antithesis, among many others. An accurate understanding of Canguilhem’s ideas demands (...) an unbiased review of Auguste Comte’s work, particularly his views on science in general, the various sciences in particular and the methods to present them, to wit, the historical and the dogmatic. We finish with a short description of our theoretical-methodological work and its implications for studies in the history of science. (shrink)