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  1. Conflict of Interest in Scientific Research in China: A Socio-Ethical Analysis of He Jiankui’s Human Genome-Editing Experiment.Jing-Bao Nie, Guangkuan Xie, Hua Chen & Yali Cong - 2020 - Journal of Bioethical Inquiry 17 (2):191-201.
    Extensive conflicts of interest at both individual and institutional levels are identifiable in scientific research and healthcare in China, as in many other parts of the world. A prominent new case from China is He Jiankui’s experiment that produced the world’s first gene-edited babies and that raises numerous ethical, political, socio-cultural, and transnational questions. Serious financial and other COI were involved in He’s genetic adventure. Using He’s infamous experiment as a case study, this paper explores the wider issue of financial (...)
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  • Synthetic Biology and the Translational Imperative.Raheleh Heidari Feidt, Marcello Ienca, Bernice Simone Elger & Marc Folcher - 2019 - Science and Engineering Ethics 25 (1):33-52.
    Advances at the interface between the biological sciences and engineering are giving rise to emerging research fields such as synthetic biology. Harnessing the potential of synthetic biology requires timely and adequate translation into clinical practice. However, the translational research enterprise is currently facing fundamental obstacles that slow down the transition of scientific discoveries from the laboratory to the patient bedside. These obstacles including scarce financial resources and deficiency of organizational and logistic settings are widely discussed as primary impediments to translational (...)
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  • Bioethics and Post-Approval Research in Translational Science.Jiin-Yu Chen & Michele Carter - 2010 - American Journal of Bioethics 10 (8):35-37.
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  • Translational Research Beyond Approval: A Two-Stage Ethics Review.Neema Sofaer & Nir Eyal - 2010 - American Journal of Bioethics 10 (8):W1-W3.
    Commentators on the ethics of translational research find it morally problematic. Types of translational research are said to involve questionable benefits, special risks, additional barriers to informed consent, and severe conflicts of interest. Translational research conducted on the global poor is thought to exploit them and increase international disparities. Some commentators support especially stringent ethical review. However, such concerns are grounded only in pre-approval translational research. Whether or not T1 has these features, translational research beyond approval is unlikely to and, (...)
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  • Towards a Richer Debate on Tissue Engineering: A Consideration on the Basis of NEST-Ethics. [REVIEW]A. J. M. Oerlemans, M. E. C. van Hoek, E. van Leeuwen, S. van der Burg & W. J. M. Dekkers - 2013 - Science and Engineering Ethics 19 (3):963-981.
    In their 2007 paper, Swierstra and Rip identify characteristic tropes and patterns of moral argumentation in the debate about the ethics of new and emerging science and technologies (or “NEST-ethics”). Taking their NEST-ethics structure as a starting point, we considered the debate about tissue engineering (TE), and argue what aspects we think ought to be a part of a rich and high-quality debate of TE. The debate surrounding TE seems to be predominantly a debate among experts. When considering the NEST-ethics (...)
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  • Reengineering Biomedical Translational Research with Engineering Ethics.Mary E. Sunderland & Rahul Uday Nayak - 2015 - Science and Engineering Ethics 21 (4):1019-1031.
    It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might apply to engineers. In this paper we examine engineers as key translators and argue that they are well positioned to ask transformative ethical questions. Asking engineers to (...)
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  • Beyond Bench and Bedside: Disentangling the Concept of Translational Research.Anna Laura van der Laan & Marianne Boenink - 2015 - Health Care Analysis 23 (1):1-18.
    The label ‘Translational Research’ (TR) has become ever more popular in the biomedical domain in recent years. It is usually presented as an attempt to bridge a supposed gap between knowledge produced at the lab bench and its use at the clinical bedside. This is claimed to help society harvest the benefits of its investments in scientific research. The rhetorical as well as moral force of the label TR obscure, however, that it is actually used in very different ways. In (...)
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  • Towards a Richer Debate on Tissue Engineering: A Consideration on the Basis of NEST-Ethics. [REVIEW]A. J. M. Oerlemans, M. E. C. Hoek, E. Leeuwen, S. Burg & W. J. M. Dekkers - 2013 - Science and Engineering Ethics 19 (3):963-981.
    In their 2007 paper, Swierstra and Rip identify characteristic tropes and patterns of moral argumentation in the debate about the ethics of new and emerging science and technologies (or “NEST-ethics”). Taking their NEST-ethics structure as a starting point, we considered the debate about tissue engineering (TE), and argue what aspects we think ought to be a part of a rich and high-quality debate of TE. The debate surrounding TE seems to be predominantly a debate among experts. When considering the NEST-ethics (...)
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  • Beyond Bench and Bedside: Disentangling the Concept of Translational Research. [REVIEW]Anna Laura Laan & Marianne Boenink - 2012 - Health Care Analysis (1):1-18.
    The label ‘Translational Research’ (TR) has become ever more popular in the biomedical domain in recent years. It is usually presented as an attempt to bridge a supposed gap between knowledge produced at the lab bench and its use at the clinical bedside. This is claimed to help society harvest the benefits of its investments in scientific research. The rhetorical as well as moral force of the label TR obscure, however, that it is actually used in very different ways. In (...)
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  • Ethical Analysis of Translational Research is More Complex Than Distinguishing T1 From T.Bill Allen - 2010 - American Journal of Bioethics 10 (8):33-35.
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  • Impediments to “T2” Research: Are Ethics Really to Blame?Wendy Lipworth & Ian Kerridge - 2010 - American Journal of Bioethics 10 (8):39-40.
  • Translational Ethics: An Analytical Framework of Translational Movements Between Theory and Practice and a Sketch of a Comprehensive Approach.Kristine Bærøe - 2014 - BMC Medical Ethics 15 (1):71.
    Translational research in medicine requires researchers to identify the steps to transfer basic scientific discoveries from laboratory benches to bedside decision-making, and eventually into clinical practice. On a parallel track, philosophical work in ethics has not been obliged to identify the steps to translate theoretical conclusions into adequate practice. The medical ethicist A. Cribb suggested some years ago that it is now time to debate ‘the business of translational’ in medical ethics. Despite the very interesting and useful perspective on the (...)
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  • Diverse Ethics of Translational Research in the Developing World.Trudie Lang - 2010 - American Journal of Bioethics 10 (8):41-42.
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  • The Ethical Urgency of Advancing Implementation Science.Mildred Z. Solomon - 2010 - American Journal of Bioethics 10 (8):31-32.
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  • Community Engagement and the Ethics of Global, Translational Research: A Response to Sofaer and Eyal.John Lynch & Monica Mitchell - 2010 - American Journal of Bioethics 10 (8):37-38.
  • Post-Approval Translational Research Itself Has Diverse Ethics.Joia Mukherjee - 2010 - American Journal of Bioethics 10 (8):43-44.