Berichte zur Wissenschaftsgeschichte, Volume 45, Issue 3, Page 332-343, September 2022.

This paper extends previous arguments against the assumption that the study of variation at the molecular level was instigated with a view to solving an internal conflict between the balance and classical schools of population genetics. It does so by focusing on the intersection of basic research in protein chemistry and the molecular approach to disease with the enactment of global health campaigns during the Cold War period. The paper connects advances in research on protein structure and function as reflected (...) in Christian Anfinsen’s The molecular basis of evolution, with a political reading of Emilé Zuckerkandl and Linus Pauling’s identification of molecular disease and evolution. Beyond atomic fallout, these advances constituted a rationale for the promotion of genetic surveys of human populations in the Third World, in connection with international health programs. Light is shed not only on the experimental roots of the molecular challenge but on the broader geopolitical context where the rising role of biomedicine and public health had an impact on evolutionary biology. (shrink)

How do nuclear technologies become commonplace? How have the borders between the exceptional and the banal been drawn and redrawn over the last 70 years in order to make nuclear energy part of everyday life? This special issue analyzes the role of fun and display, broadly construed, in shaping the cultural representation and the material circulation (or non-circulation) of nuclear technologies. Four case studies, covering the United States, Great Britain, Portugal, Spain, and Ukraine from the 1950s to the 2000s, explore (...) how specific forms of public display and playful practices of cultural production were used as means to banalize (or de-banalize) nuclear energy. This introduction addresses the main theoretical and historiographical signposts of the special issue and outlines the different ways in which the articles explore them. (shrink)

Alongside the renowned male pioneers of medical cytogenetics, many women participated in investigations at the laboratory bench and the bedside, both in Europe and the Americas. These women were committed to this new biological and clinical practice—cytogenetics, the origins of contemporary genetic diagnosis—and contributed to the creation of new biological concepts and settings centered on the study of chromosome imaging. This paper will review the contributions made by a group of woman scientists from a wide geographical distribution, situating their names (...) and research agendas within the history of a field dating back to early plant and insect cytogenetics. Rather than an exhaustive compendium of women geneticists, this essay presents a kind of historical reconstruction that can be achieved by placing women at center stage in their geographies and networks of circulating cytogenetic knowledge and practices thereby relating a history of genetic images though the work carried out by women, retrieving their agency and constructing an inclusive history of an influential contemporary biomedical practice as it gained increasing influence in the laboratory and the clinic. (shrink)

Narratives surrounding ionizing radiation have often minimized radioactivity’s impact on the health of human and non-human animals and the natural environment. Many Cold War research policies, practices, and interpretations drove nuclear technology forward by institutionally obscuring empirical evidence of radiation’s disproportionate and low-dose harm—a legacy we still confront. Women, children, and pregnancy development are particularly sensitive to exposure from radioactivity, suffering more damage per dose than adult males, even down to small doses, making low doses a cornerstone of concern. Evidence (...) of compounding generational damage could indicate increased sensitivity through heritable impact. This essay examines the existing empirical evidence demonstrating these sensitivities, and how research institutions and regulatory authorities have devalued them, willingly sacrificing health in the service of maintaining and expanding nuclear technology. Radiation’s disproportionate impacts should now be the research and policy focus, as society is poised to make crucial and long-lasting decisions regarding climate change mitigation and future energy sources. (shrink)

The postwar investments by several governments into the development of atomic energy for military and peaceful uses fuelled the fears not only of the exposure to acute doses of radiation as could be expected from nuclear accidents or atomic warfare but also of the long-term effects of low-dose exposure to radiation. Following similar studies pursued under the aegis of the Manhattan Project in the United States, the “genetics experiment” discussed by scientists and government officials in Britain soon after the war, (...) consisted in large-scale low-dose irradiation experiments of laboratory animals to assess the effects of such exposures on humans. The essay deals with the history of that project and its impact on postwar genetics. It argues that radiobiological concerns driven by atomic politics lay at the heart of much genetics research after the war and that the atomic links are crucial to understand how genetics became an overriding concern in the late 20th century. (shrink)

This paper describes the activities of amateur plant breeders and their application of various methods and technologies derived from genetics research over the course of the twentieth century. These ranged from selection and hybridization to more interventionist approaches such as radiation treatment to induce genetic mutations and chemical manipulation of chromosomes. I argue that these activities share characteristics with twenty-first-century do-it-yourself (DIY) biology (a recent upswing in amateur experimental biology) as well as other amateur science and technology of the twentieth (...) century. The characterization of amateur plant breeding as amateur experimental biology offers a corrective to a dominant narrative within the history of biology, in which the turn to experimental research in the early twentieth century is thought to have served as an obvious dividing line between amateur and professional activities. Considered alongside other better-known amateur efforts, it also suggests that we might gain something by taking a more unified approach to the study of amateur science and technology. (shrink)

The postwar investments by several governments into the development of atomic energy for military and peaceful uses fuelled the fears not only of the exposure to acute doses of radiation as could be expected from nuclear accidents or atomic warfare but also of the long-term effects of low-dose exposure to radiation. Following similar studies pursued under the aegis of the Manhattan Project in the United States, the "genetics experiment" discussed by scientists and government officials in Britain soon after the war, (...) consisted in large-scale low-dose irradiation experiments of laboratory animals to assess the effects of such exposures on humans. The essay deals with the history of that project and its impact on postwar genetics. It argues that radiobiological concerns driven by atomic politics lay at the heart of much genetics research after the war and that the atomic links are crucial to understand how genetics became an overriding concern in the late 20th century. (shrink)

After WWII, global concerns about the uses of nuclear energy and radiation sources in agriculture, medicine, and industry brought about calls for radiation protection. At the beginning of the 1960s radiation protection involved the identification and measurement of all sources of radiation to which a population was exposed, and the evaluation and assessment of populations in terms of the biological hazard their exposure posed. Mexico was not an exception to this international trend. This paper goes back to the origins of (...) the first studies on the effects of radiation and on radioprotective compounds in the Genetics and Radiobiology Program of the National Commission of Nuclear Energy founded in 1960, at a time when the effects of radiation on living beings and radiation protection demanded the attention of highly localized groups of scientists and the creation of international as well as national institutions, and its connection to dosimetry and radiation protection until the 1990s. This historical reconstruction examines the circulation of knowledge, scientists, and their material and cognitive resources, to show that radiobiology, with dosimetry and radiation protection as cases in point, not only were carried out with high international standards in parallel with international agencies, but also reflected local material needs, including the standardization of new experimental techniques. (shrink)