The question of the meaning of life has long been thought to be closely intertwined with that of the existence of God. I offer a new theistic, anti-naturalist argument from the meaning of life. It is argued that the desire for life is irrational on naturalism, since there would be no good reason to believe that life is worthwhile on the whole if naturalism were true. As I show, the same cannot be argued of theism. Since it is clear that (...) the desire for life is not irrational, it is concluded that we have strong reason to prefer theism over naturalism. (shrink)