Thomas Nickles challenges my thesis that innovative discoveries can be based on deliberately chosen problems and research strategies. He suggests that all significant innovation can be seen as such only in retrospect and that its generation must be serendipitous. Here I argue in response that significant innovations can and do often arise from self conscious critical appraisal of orthodox practice combined with regulated though speculative abductive argumentation to alternative explanatory schemata. Orthodox practice is not based upon monolithic systems of belief (...) about the subject of inquiry. Rather major domains of scientific practice often are approached from different conceptualizations that provide grounds for critical dialectic and consilient empirical information. Abductive arguments that meet appropriate conditions of likelihood, probability and analogy are an important means of justifying allocating resources to innovative practices that have yet to produce products that can rival those of established orthodoxy. (shrink)

Scientific thought is characterized in general as methodical and rational. I would like to present here an opposing view which treats science as a non-systematic activity, where serendipity, tinkering and imitation, rather than so-called rational thought, characterizes it. All these kinds of acts, which are considered to be a-rational, are related to an evolutionary view of science. I will deal here with a version of evolutionary epistemology as applied to science, integrated with the concept uf "meme". Richard Dawkins, who coined (...) the term "meme", treats memes as units of information which propagate in the meme-pool by leaping from brain to brain. The way that memes replicate is through imitation. Examples for this phenomenon in science are illustrated by some historical cases. In particular, I will deal with the evolution of theories of "internal symmetries" in particle physics. Memetics is the counterpart of genetics in the cultural arena. In its application to science, it deals with the manner memes/ideas spread in scientific communities. (shrink)

The way scientific discovery has been conceptualized has changed drastically in the last few decades: its relation to logic, inference, methods, and evolution has been deeply reloaded. The ‘philosophical matrix’ moulded by logical empiricism and analytical tradition has been challenged by the ‘friends of discovery’, who opened up the way to a rational investigation of discovery. This has produced not only new theories of discovery, but also new ways of practicing it in a rational and more systematic way. Ampliative rules, (...) methods, heuristic procedures and even a logic of discovery have been investigated, extracted, reconstructed and refined. The outcome is a ‘scientific discovery revolution’: not only a new way of looking at discovery, but also a construction of tools that can guide us to discover something new. This is a very important contribution of philosophy of science to science, as it puts the former in a position not only to interpret what scientists do, but also to provide and improve tools that they can employ in their activity. (shrink)

In the centenary year of Turing’s birth, a lot of good things are sure to be written about him. But it is hard to find something new to write about Turing. This is the biggest merit of this article: it shows how von Neumann’s architecture of the modern computer is a serendipitous consequence of the universal Turing machine, built to solve a logical problem.

This paper presents the manner in which the DNA, the molecule of life, was discovered. Unlike what many people, even biologists, believe, it was Johannes Friedrich Miescher who originally discovered and isolated nuclein, currently known as DNA, in 1869, 75 years before Watson and Crick unveiled its structure. Also, in this paper we show, and above all demonstrate, the serendipity of this major discovery. Like many of his contemporaries, Miescher set out to discover how cells worked by means of studying (...) and analysing their proteins. During this arduous task, he detected an unexpected substance of unpredicted properties. This new substance precipitated when he added acid to the solution and it dissolved again when adding alkali. Unexpectedly and by a mere fluke, Miescher was the first person to obtain a DNA precipitate. The paper then presents the term serendipity and discusses how it has influenced the discovery of other important scientific milestones. Finally, we address the question of whether serendipitous discoveries can be nurtured and what role the computer could play in this process. (shrink)

Scientific thought is generally characterized as methodical and rational. I would like to present here an opposing view which treats science as a non-systematic activity, where serendipity, tinkering and imitation, rather than so-called rational thought, characterizes it. All these kinds of acts, which are considered to be a-rational, are related to an evolutionary view of science. I will deal here with a version of evolutionary epistemology as applied to science. The combination of variation and competition for survival is analogous to (...) the elements of Darwinian evolution. I will give some examples for this phenomenon in science from historical cases and Examples for this phenomenon in science are illustrated by some historical cases, in particular by the evolution of theories of internal symmetries in particle physics. (shrink)