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  1. Explanations in cognitive science: unification versus pluralism.Marcin Miłkowski & Mateusz Hohol - 2020 - Synthese 199 (Suppl 1):1-17.
    The debate between the defenders of explanatory unification and explanatory pluralism has been ongoing from the beginning of cognitive science and is one of the central themes of its philosophy. Does cognitive science need a grand unifying theory? Should explanatory pluralism be embraced instead? Or maybe local integrative efforts are needed? What are the advantages of explanatory unification as compared to the benefits of explanatory pluralism? These questions, among others, are addressed in this Synthese’s special issue. In the introductory paper, (...)
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  • From Computer Metaphor to Computational Modeling: The Evolution of Computationalism.Marcin Miłkowski - 2018 - Minds and Machines 28 (3):515-541.
    In this paper, I argue that computationalism is a progressive research tradition. Its metaphysical assumptions are that nervous systems are computational, and that information processing is necessary for cognition to occur. First, the primary reasons why information processing should explain cognition are reviewed. Then I argue that early formulations of these reasons are outdated. However, by relying on the mechanistic account of physical computation, they can be recast in a compelling way. Next, I contrast two computational models of working memory (...)
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  • From Wide Cognition to Mechanisms: A Silent Revolution.Marcin Miłkowski, Robert Clowes, Zuzanna Rucińska, Aleksandra Przegalińska, Tadeusz Zawidzki, Joel Krueger, Adam Gies, Marek McGann, Łukasz Afeltowicz, Witold Wachowski, Fredrik Stjernberg, Victor Loughlin & Mateusz Hohol - 2018 - Frontiers in Psychology 9.
    In this paper, we argue that several recent ‘wide’ perspectives on cognition (embodied, embedded, extended, enactive, and distributed) are only partially relevant to the study of cognition. While these wide accounts override traditional methodological individualism, the study of cognition has already progressed beyond these proposed perspectives towards building integrated explanations of the mechanisms involved, including not only internal submechanisms but also interactions with others, groups, cognitive artifacts, and their environment. The claim is substantiated with reference to recent developments in the (...)
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  • Computational Mechanisms and Models of Computation.Marcin Miłkowski - 2014 - Philosophia Scientiae 18:215-228.
    In most accounts of realization of computational processes by physical mechanisms, it is presupposed that there is one-to-one correspondence between the causally active states of the physical process and the states of the computation. Yet such proposals either stipulate that only one model of computation is implemented, or they do not reflect upon the variety of models that could be implemented physically. -/- In this paper, I claim that mechanistic accounts of computation should allow for a broad variation of models (...)
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  • Computational Mechanisms and Models of Computation.Marcin Miłkowski - 2014 - Philosophia Scientiae 18:215-228.
    In most accounts of realization of computational processes by physical mechanisms, it is presupposed that there is one-to-one correspondence between the causally active states of the physical process and the states of the computation. Yet such proposals either stipulate that only one model of computation is implemented, or they do not reflect upon the variety of models that could be implemented physically. In this paper, I claim that mechanistic accounts of computation should allow for a broad variation of models of (...)
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  • The Non-mechanistic Option: Defending Dynamical Explanations.Russell Meyer - 2018 - British Journal for the Philosophy of Science 71 (3):959-985.
    This article demonstrates that non-mechanistic, dynamical explanations are a viable approach to explanation in the special sciences. The claim that dynamical models can be explanatory without reference to mechanisms has previously been met with three lines of criticism from mechanists: the causal relevance concern, the genuine laws concern, and the charge of predictivism. I argue, however, that these mechanist criticisms fail to defeat non-mechanistic, dynamical explanation. Using the examples of Haken et al.’s model of bimanual coordination, and Thelen et al.’s (...)
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  • Inheritance as Evolved and Evolving Physiological Processes.Francesca Merlin & Livio Riboli-Sasco - 2020 - Acta Biotheoretica 69 (3):417-433.
    In this paper, we adopt a physiological perspective in order to produce an intelligible overview of biological transmission in all its diversity. This allows us to put forward the analysis of transmission mechanisms, with the aim of complementing the usual focus on transmitted factors. We underline the importance of the structural, dynamical, and functional features of transmission mechanisms throughout organisms’ life cycles in order to answer to the question of what is passed on across generations, how and why. On this (...)
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  • The causal structure of mechanisms.Peter Menzies - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (4):796-805.
    Recently, a number of philosophers of science have claimed that much explanation in the sciences, especially in the biomedical and social sciences, is mechanistic explanation. I argue the account of mechanistic explanation provided in this tradition has not been entirely satisfactory, as it has neglected to describe in complete detail the crucial causal structure of mechanistic explanation. I show how the interventionist approach to causation, especially within a structural equations framework, provides a simple and elegant account of the causal structure (...)
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  • Mechanism Discovery and Design Explanation: Where Role Function Meets Biological Advantage Function.Julie Mennes & Dingmar Eck - 2018 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 49 (3):413-434.
    In the recent literature on explanation in biology, increasing attention is being paid to the connection between design explanation and mechanistic explanation, viz. the role of design principles and heuristics for mechanism discovery and mechanistic explanation. In this paper we extend the connection between design explanation and mechanism discovery by prizing apart two different types of design explanation and by elaborating novel heuristics that one specific type offers for mechanism discovery across species. We illustrate our claims in terms of two (...)
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  • Autopoiesis, biological autonomy and the process view of life.Anne Sophie Meincke - 2018 - European Journal for Philosophy of Science 9 (1):5.
    In recent years, an increasing number of theoretical biologists and philosophers of biology have been opposing reductionist research agendas by appealing to the concept of biological autonomy which draws on the older concept of autopoiesis. In my paper, I investigate some of the ontological implications of this approach. The emphasis on autonomy and autopoiesis, together with the associated idea of organisational closure, might evoke the impression that organisms are to be categorised ontologically as substances: ontologically independent, well-individuated, discrete particulars. However, (...)
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  • Autopoiesis, biological autonomy and the process view of life.Anne Sophie Meincke - 2018 - European Journal for Philosophy of Science 9 (1):1-16.
    In recent years, an increasing number of theoretical biologists and philosophers of biology have been opposing reductionist research agendas by appealing to the concept of biological autonomy which draws on the older concept of autopoiesis. In my paper, I investigate some of the ontological implications of this approach. The emphasis on autonomy and autopoiesis, together with the associated idea of organisational closure, might evoke the impression that organisms are to be categorised ontologically as substances: ontologically independent, well-individuated, discrete particulars. However, (...)
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  • A weakened mechanism is still a mechanism: On the causal role of absences in mechanistic explanation.Alexander Mebius - 2014 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 45:43-48.
    Much contemporary debate on the nature of mechanisms centers on the issue of modulating negative causes. One type of negative causability, which I refer to as "causation by absence," appears difficult to incorporate into modern accounts of mechanistic explanation. This paper argues that a recent attempt to resolve this problem, proposed by Benjamin Barros, requires improvement as it overlooks the fact that not all absences qualify as sources of mechanism failure. I suggest that there are a number of additional types (...)
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  • A weakened mechanism is still a mechanism: On the causal role of absences in mechanistic explanation.Alexander Mebius - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 45 (1):43-48.
    Much contemporary debate on the nature of mechanisms centers on the issue of modulating negative causes. One type of negative causability, which I refer to as “causation by absence,” appears difficult to incorporate into modern accounts of mechanistic explanation. This paper argues that a recent attempt to resolve this problem, proposed by Benjamin Barros, requires improvement as it overlooks the fact that not all absences qualify as sources of mechanism failure. I suggest that there are a number of additional types (...)
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  • Research gaps in the philosophy of evidence‐based medicine.Alexander Mebius, Ashley Graham Kennedy & Jeremy Howick - 2016 - Philosophy Compass 11 (11):757-771.
    Increasing philosophical attention is being directed to the rapidly growing discipline of evidence-based medicine. Philosophical discussions of EBM, however, remain narrowly focused on randomization, mechanisms, and the sociology of EBM. Other aspects of EBM have been all but ignored, including the nature of clinical reasoning and the question of whether it can be standardized; the application of EBM principles to the logic, value, and ethics of diagnosis and prognosis; evidence synthesis ; and the nature and ethics of placebo controls. Philosophical (...)
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  • Development and mechanistic explanation.Fabrizzio Mc Manus - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (2):532-541.
  • Development and mechanistic explanation.Fabrizzio Mc Manus - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (2):532-541.
  • Response to Henschen: causal pluralism in macroeconomics.Mariusz Maziarz & Robert Mróz - 2019 - Journal of Economic Methodology 27 (2):164-178.
    In his recent paper in the Journal of Economic Methodology, Tobias Henschen puts forth a manipulationist definition of macroeconomic causality that strives for adequacy. As the notion of ‘adequacy’...
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  • Resolving empirical controversies with mechanistic evidence.Mariusz Maziarz - 2021 - Synthese 199 (3-4):9957-9978.
    The results of econometric modeling are fragile in the sense that minor changes in estimation techniques or sample can lead to statistical models that support inconsistent causal hypotheses. The fragility of econometric results undermines making conclusive inferences from the empirical literature. I argue that the program of evidential pluralism, which originated in the context of medicine and encapsulates to the normative reading of the Russo-Williamson Thesis that causal claims need the support of both difference-making and mechanistic evidence, offers a ground (...)
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  • Causal Pluralism in Medicine and its Implications for Clinical Practice.Mariusz Maziarz - forthcoming - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie:1-22.
    The existing philosophical views on what is the meaning of causality adequate to medicine are vastly divided. We approach this question and offer two arguments in favor of pluralism regarding concepts of causality. First, we analyze the three main types of research designs (randomized-controlled trials, observational epidemiology and laboratory research). We argue, using examples, that they allow for making causal conclusions that are best understood differently in each case (in agreement with a version of manipulationist, probabilistic and mechanistic definitions, respectively). (...)
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  • Mechanisms in the analysis of social macro-phenomena.Renate Mayntz - 2004 - Philosophy of the Social Sciences 34 (2):237-259.
    mechanism" is frequently encountered in the social science literature, but there is considerable confusion about the exact meaning of the term. The article begins by addressing the main conceptual issues. Use of this term is the hallmark of an approach that is critical of the explanatory deficits of correlational analysis and of the covering-law model, advocating instead the causal reconstruction of the processes that account for given macro-phenomena. The term "social mechanisms" should be used to refer to recurrent processes generating (...)
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  • The Causal Explanatory Functions of Medical Diagnoses.Hane Htut Maung - 2017 - Theoretical Medicine and Bioethics 38 (1):41-59.
    Diagnoses in medicine are often taken to serve as explanations of patients’ symptoms and signs. This article examines how they do so. I begin by arguing that although some instances of diagnostic explanation can be formulated as covering law arguments, they are explanatory neither in virtue of their argumentative structures nor in virtue of general regularities between diagnoses and clinical presentations. I then consider the theory that medical diagnoses explain symptoms and signs by identifying their actual causes in particular cases. (...)
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  • Diagnosis and Causal Explanation in Psychiatry.Hane Htut Maung - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 60 (C):15-24.
    In clinical medicine, a diagnosis can offer an explanation of a patient's symptoms by specifying the pathology that is causing them. Diagnoses in psychiatry are also sometimes presented in clinical texts as if they pick out pathological processes that cause sets of symptoms. However, current evidence suggests the possibility that many diagnostic categories in psychiatry are highly causally heterogeneous. For example, major depressive disorder may not be associated with a single type of underlying pathological process, but with a range of (...)
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  • Three legs of the missing heritability problem.Lucas J. Matthews & Eric Turkheimer - 2022 - Studies in History and Philosophy of Science Part A 93 (C):183-191.
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  • On mechanistic reasoning in unexpected places: the case of population genetics.Lucas J. Matthews - 2017 - Biology and Philosophy 32 (6):999-1018.
    A strong case has been made for the role and value of mechanistic reasoning in process-oriented sciences, such as molecular biology and neuroscience. This paper shifts focus to assess the role of mechanistic reasoning in an area where it is neither obvious nor expected: population genetics. Population geneticists abstract away from the causal-mechanical details of individual organisms and, instead, use mathematics to describe population-level, statistical phenomena. This paper, first, develops a framework for the identification of mechanistic reasoning where it is (...)
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  • On closing the gap between philosophical concepts and their usage in scientific practice: a lesson from the debate about natural selection as a mechanism.Lucas J. Matthews - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 55:21-28.
    In addition to theorizing about the role and value of mechanisms in scientific explanation or the causal structure of the world, there is a fundamental task of getting straight what a ‘mechanism’ is in the first place. Broadly, this paper is about the challenge of application: the challenge of aligning one's philosophical account of a scientific concept with the manner in which that concept is actually used in scientific practice. This paper considers a case study of the challenge of application (...)
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  • Mechanistic models of population-level phenomena.John Matthewson & Brett Calcott - 2011 - Biology and Philosophy 26 (5):737-756.
    This paper is about mechanisms and models, and how they interact. In part, it is a response to recent discussion in philosophy of biology regarding whether natural selection is a mechanism. We suggest that this debate is indicative of a more general problem that occurs when scientists produce mechanistic models of populations and their behaviour. We can make sense of claims that there are mechanisms that drive population-level phenomena such as macroeconomics, natural selection, ecology, and epidemiology. But talk of mechanisms (...)
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  • Mechanistic Explanation in Systems Biology: Cellular Networks.Dana Matthiessen - 2017 - British Journal for the Philosophy of Science 68 (1):1-25.
    It is argued that once biological systems reach a certain level of complexity, mechanistic explanations provide an inadequate account of many relevant phenomena. In this article, I evaluate such claims with respect to a representative programme in systems biological research: the study of regulatory networks within single-celled organisms. I argue that these networks are amenable to mechanistic philosophy without need to appeal to some alternate form of explanation. In particular, I claim that we can understand the mathematical modelling techniques of (...)
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  • Embedded Mechanisms and Phylogenetics.Lucas J. Matthews - 2015 - Philosophy of Science 82 (5):1116-1126.
    A strong case has been made for the role and value of mechanistic explanation in neuroscience and molecular biology. A similar demonstration in other domains of scientific investigation, however, remains an important challenge of scope for the new mechanists. This article helps answer that challenge by demonstrating one valuable role mechanisms play in phylogenetics. Using the transition/transversion rate parameter as a case example, this article argues that models embedded with mechanisms produce stronger phylogenetic tree hypotheses, as measured by maximum likelihood (...)
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  • Across the great divide: pluralism and the hunt for missing heritability.Lucas J. Matthews & Eric Turkheimer - 2019 - Synthese 198 (3):2297-2311.
    Genetic explanation of complex human behavior presents an excellent test case for pluralism. Although philosophers agree that successful scientific investigation of behavior is pluralistic, there remains disagreement regarding integration and elimination—is the plurality of approaches here to stay, or merely a waystation on the road to monism? In this paper we introduce an issue taken very seriously by scientists yet mostly ignored by philosophers—the missing heritability problem—and assess its implications for disagreement among pluralists. We argue that the missing heritability problem, (...)
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  • AI and Philosophy of Science人工知能と科学哲学.Masahiro Matsuo - 2017 - Kagaku Tetsugaku 50:71-84.
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  • Horizon for Scientific Practice: Scientific Discovery and Progress.James A. Marcum - 2010 - International Studies in the Philosophy of Science 24 (2):187-215.
    In this article, I introduce the notion of horizon for scientific practice (HSP), representing limits or boundaries within which scientists ply their trade, to facilitate analysis of scientific discovery and progress. The notion includes not only constraints that delimit scientific practice, e.g. of bringing experimentation to a temporary conclusion, but also possibilities that open up scientific practice to additional scientific discovery and to further scientific progress. Importantly, it represents scientific practice as a dynamic and developmental integration of activities to investigate (...)
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  • Experimental Series and the Justification of Temin’s DNA Provirus Hypothesis.James A. Marcum - 2007 - Synthese 154 (2):259 - 292.
    A notion of experimental series is developed, in which experiments or experimental sets are connected through experimental suggestions arising from previous experimental outcomes. To that end, the justification of Howard Temin’s DNA provirus hypothesis is examined. The hypothesis originated with evidence from two exploratory experimental sets on an oncogenic virus and was substantiated by including evidence from three additional experimental sets. Collectively these sets comprise an experimental series and the accumulative evidence from the series was adequate to justify the hypothesis (...)
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  • Experimental Series and the Justification of Temin’s DNA Provirus Hypothesis.James A. Marcum - 2007 - Synthese 154 (2):259-292.
    A notion of experimental series is developed, in which experiments or experimental sets are connected through experimental suggestions arising from previous experimental outcomes. To that end, the justification of Howard Temin's DNA provirus hypothesis is examined. The hypothesis originated with evidence from two exploratory experimental sets on an oncogenic virus and was substantiated by including evidence from three additional experimental sets. Collectively these sets comprise an experimental series and the accumulative evidence from the series was adequate to justify the hypothesis (...)
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  • Explanatory pluralism and complementarity: From autonomy to integration.Caterina Marchionni - 2008 - Philosophy of the Social Sciences 38 (3):314-333.
    Philosophers of the social sciences are increasingly convinced that macro-and micro-explanations are complementary. Whereas macro-explanations are broad, micro-explanations are deep. I distinguish between weak and strong complementarity: Strongly complementary explanations improve one another when integrated, weakly complementary explanations do not. To demonstrate the explanatory autonomy of different levels of explanation, explanatory pluralists mostly presuppose the weak form of complementarity. By scrutinizing the notions of explanatory depth and breadth, I argue that macro- and micro-accounts of the same phenomenon are more often (...)
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  • Challenging the Mechanistic View of Integration in Psychiatry.Caterina Marchionni - forthcoming - British Journal for the Philosophy of Science.
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  • Computers as Interactive Machines: Can We Build an Explanatory Abstraction?Alice Martin, Mathieu Magnaudet & Stéphane Conversy - 2023 - Minds and Machines 33 (1):83-112.
    In this paper, we address the question of what current computers are from the point of view of human-computer interaction. In the early days of computing, the Turing machine (TM) has been the cornerstone of the understanding of computers. The TM defines what can be computed and how computation can be carried out. However, in the last decades, computers have evolved and increasingly become interactive systems, reacting in real-time to external events in an ongoing loop. We argue that the TM (...)
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  • Explanations of Meaningful Actions.C. Mantzavinos - 2012 - Philosophy of the Social Sciences 42 (2):224-238.
    There is a long tradition in philosophy and the social sciences that emphasizes the meaningfulness of human action. This tradition doubts or even negates the possibility of causal explanations of human action precisely on the basis that human actions have meaning. This article provides an argument in favor of methodological naturalism in the social sciences. It grants the main argument of the Interpretivists, that is, that human actions are meaningful, but it shows how a transformation of a "nexus of meaning" (...)
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  • Explanatory Games.C. Mantzavinos - 2013 - Journal of Philosophy 110 (11):606-632.
    A philosophical theory of explanation should provide solutions to a series of problems, both descriptive and normative. The aim of this essay is to establish the claim that this can be best done if one theorizes in terms of explanatory games rather than focusing on the explication of the concept of explanation. The position that is adopted is that of an explanatory pluralism and it is elaborated in terms of the rules that incorporate the normative standards that guide the processes (...)
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  • Austrian Economics and Critical Realism.Peter Manicas - 2008 - Journal of Critical Realism 7 (2):208-234.
    From the perspective of a realist philosophy of social science, the recent explosion of criticisms of mainstream economics, including reinvigorated Austrian criticism, provides what seems like a rich opportunity to join what are too often disjoined disciplinary interests and inquirers, and also to extend the arguments not only as regards the realist theory of social science, but also as regards the implications of this approach for economics. I begin with a minimum sketch of key features of realist philosophy of science (...)
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  • Toward Analog Neural Computation.Corey J. Maley - 2018 - Minds and Machines 28 (1):77-91.
    Computationalism about the brain is the view that the brain literally performs computations. For the view to be interesting, we need an account of computation. The most well-developed account of computation is Turing Machine computation, the account provided by theoretical computer science which provides the basis for contemporary digital computers. Some have thought that, given the seemingly-close analogy between the all-or-nothing nature of neural spikes in brains and the binary nature of digital logic, neural computation could be a species of (...)
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  • Get the Latest Upgrade: Functionalism 6.3.1.Corey Maley & Gualtiero Piccinini - 2013 - Philosophia Scientae 17 (2):135-149.
    Functionalism is a popular solution to the mind–body problem. It has a number of versions. We outline some of the major releases of functionalism, listing some of their important features as well as some of the bugs that plagued these releases. We outline how different versions are related. Many have been pessimistic about functionalism’s prospects, but most criticisms have missed the latest upgrades. We end by suggesting a version of functionalism that provides a complete account of the mind.
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  • Einstein’s Theory of Theories and Mechanicism.Diego Maltrana, Manuel Herrera & Federico Benitez - 2022 - International Studies in the Philosophy of Science 35 (2):153-170.
    One of the most important contributions of Einstein to the philosophy of science is the distinction between two types of scientific theories: ‘principle’ and ‘constructive’ theories. More recently, Flores proposed a more general distinction, classifying scientific theories by their functional role into ‘framework’ and ‘interaction’ theories, attempting to solve some inadequacies in Einstein’s proposal. Here, based on an epistemic criterion, we present a generalised distinction which is an improvement over Flores approach. In this work (i) we evaluate the shortcomings related (...)
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  • Mario Bunge (1919–2020): Conjoining Philosophy of Science and Scientific Philosophy.Martin Mahner - 2021 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 52 (1):3-23.
    The leitmotif of Mario Bunge’s work was that the philosophy of science should be informed by a comprehensive scientific philosophy, and vice versa; with both firmly rooted in realism and materialism. Now Bunge left such a big oeuvre, comprising more than 70 books and hundreds of articles, that it is impossible to review it in its entirety. In addition to biographical remarks, this obituary will therefore restrict itself to some select issues of his philosophy: his scientific metaphysics, his philosophy of (...)
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  • Theory and Method in the Neurosciences.Gualtiero Piccinini - 2001 - Philosophy of Science 68 (4):584-588.
  • Modeling systems-level dynamics: Understanding without mechanistic explanation in integrative systems biology.Miles MacLeod & Nancy J. Nersessian - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 49:1-11.
  • Activities and causation: The metaphysics and epistemology of mechanisms.Peter Machamer - 2004 - International Studies in the Philosophy of Science 18 (1):27 – 39.
    This article deals with mechanisms conceived as composed of entities and activities. In response to many perplexities about the nature of activities, a number of arguments are developed concerning their epistemic and ontological status. Some questions concerning the relations between cause and causal explanation and mechanisms are also addressed.
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  • Structures, dynamics and mechanisms in neuroscience: an integrative account.Holger Lyre - 2018 - Synthese 195 (12):5141-5158.
    Proponents of mechanistic explanations have recently proclaimed that all explanations in the neurosciences appeal to mechanisms. The purpose of the paper is to critically assess this statement and to develop an integrative account that connects a large range of both mechanistic and dynamical explanations. I develop and defend four theses about the relationship between dynamical and mechanistic explanations: that dynamical explanations are structurally grounded, that they are multiply realizable, possess realizing mechanisms and provide a powerful top-down heuristic. Four examples shall (...)
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  • From quorum to cooperation: lessons from bacterial sociality for evolutionary theory.Pamela Lyon - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (4):820-833.
  • From quorum to cooperation: lessons from bacterial sociality for evolutionary theory.Pamela Lyon - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (4):820-833.
  • From quorum to cooperation: Lessons from bacterial sociality for evolutionary theory.Pamela Lyon - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (4):820-833.
    Copyright © 2007 Elsevier Ltd All rights reserved.
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