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  1. Heritability.Stephen M. Downes - 2015 - Stanford Encyclopedia of Philosophy.
  • Heritability.Stephen M. Downes & Lucas J. Matthews - 2019 - Stanford Encyclopedia of Philosophy.
    Lucas Matthews and I substantially revised my SEP entry on Heritability. This version includes discussion of the missing heritability problem and other issues that arise from the use of Genome Wide Association Studies by Behavioral Geneticists.
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  • The Meaning of "Cause" in Genetics.Kate E. Lynch - 2021 - Combining Human Genetics and Causal Inference to Understand Human Disease and Development. Cold Spring Harbor Perspectives in Medicine.
    Causation has multiple distinct meanings in genetics. One reason for this is meaning slippage between two concepts of the gene: Mendelian and molecular. Another reason is that a variety of genetic methods address different kinds of causal relationships. Some genetic studies address causes of traits in individuals, which can only be assessed when single genes follow predictable inheritance patterns that reliably cause a trait. A second sense concerns the causes of trait differences within a population. Whereas some single genes can (...)
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  • Three Legs of the Missing Heritability Problem.Lucas J. Matthews & Eric Turkheimer - 2022 - Studies in History and Philosophy of Science Part A 93:183-191.
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  • Half a Century Later and We're Back Where We Started: How the Problem of Locality Turned in to the Problem of Portability.Lucas J. Matthews - 2022 - Studies in History and Philosophy of Science Part A 91:1-9.
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  • Causation and Single Nucleotide Polymorphism Heritability.Pierrick Bourrat - 2020 - Philosophy of Science 87 (5):1073-1083.
    Genome-wide association studies of human complex traits have provided us with new estimates of heritability. These estimates foreground the question of genetic causation. After having presen...
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  • Hypothesis-Driven Science in Large-Scale Studies: The Case of GWAS.Sumana Sharma & James Read - 2021 - Biology and Philosophy 36 (5):1-21.
    It is now well-appreciated by philosophers that contemporary large-scale ‘-omics’ studies in biology stand in non-trivial relationships to more orthodox hypothesis-driven approaches. These relationships have been clarified by Ratti ; however, there remains much more to be said regarding how an important field of genomics cited in that work—‘genome-wide association studies’ —fits into this framework. In the present article, we propose a revision to Ratti’s framework more suited to studies such as GWAS. In the process of doing so, we introduce (...)
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  • A Roadmap to Explanatory Pluralism: Introduction to the Topical Collection The Biology of Behaviour.Eric Muszynski & Christophe Malaterre - 2020 - Synthese 199 (1-2):1777-1789.
    Pluralism is widely appealed to in many areas of philosophy of science, though what is meant by ‘pluralism’ may profoundly vary. Because explanations of behaviour have been a favoured target for pluralistic theses, the sciences of behaviour offer a rich context in which to further investigate pluralism. This is what the topical collection The Biology of Behaviour: Explanatory pluralism across the life sciences is about. In the present introduction, we briefly review major strands of pluralist theses and their motivations. We (...)
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  • From Obesity to Energy Metabolism: Ontological Perspectives on the Metrics of Human Bodies.Davide Serpico & Andrea Borghini - 2020 - Topoi 40 (3):577-586.
    In this paper, we aim at rethinking the concept of obesity in a way that better captures the connection between underlying medical aspects, on the one hand, and an individual’s developmental history, on the other. Our proposal rests on the idea that obesity is not to be understood as a phenotypic trait or character; rather, obesity represents one of the many possible states of a more complex phenotypic trait that we call ‘energy metabolism.’ We argue that this apparently simple conceptual (...)
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  • Unifying Heritability in Evolutionary Theory.Pierrick Bourrat - 2022 - Studies in History and Philosophy of Science Part A 91:201-210.
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