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  1. Fertility preservation for transgender children and young people in paediatric healthcare: a systematic review of ethical considerations.Chanelle Warton & Rosalind J. McDougall - 2022 - Journal of Medical Ethics 48 (12):1076-1082.
    BackgroundWhile fertility preservation is recommended practice for paediatric oncology patients, it is increasingly being considered for transgender children and young people in paediatric care. This raises ethical issues for clinicians, particularly around consent and shared decision-making in this new area of healthcare.MethodsA systematic review of normative literature was conducted across four databases in June 2020 to capture ethical considerations related to fertility counselling and preservation in paediatric transgender healthcare. The text of included publications was analysed inductively, guided by the Qualitative (...)
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  • Which Framework to Use? A Systematic Review of Ethical Frameworks for the Screening or Evaluation of Health Technology Innovations.Tijs Vandemeulebroucke, Yvonne Denier, Evelyne Mertens & Chris Gastmans - 2022 - Science and Engineering Ethics 28 (3):1-35.
    Innovations permeate healthcare settings on an ever-increasing scale. Health technology innovations impact our perceptions and experiences of health, care, disease, etc. Because of the fast pace these HTIs are being introduced in different healthcare settings, there is a growing societal consensus that these HTIs need to be governed by ethical reflection. This paper reports a systematic review of argument-based literature which focused on articles reporting on ethical frameworks to screen or evaluate HTIs. To do this a four step methodology was (...)
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  • Review of the Ethical Issues of a Biomarker-Based Diagnoses in the Early Stage of Alzheimer’s Disease. [REVIEW]Gwendolien Vanderschaeghe, Kris Dierickx & Rik Vandenberghe - 2018 - Journal of Bioethical Inquiry 15 (2):219-230.
    Background: Today, many healthcare or dementia organizations, clinicians, and companies emphasize the importance of detection of Alzheimer’s disease in an early phase. This idea has gained considerable momentum due to the development of biomarkers, the recent FDA and EMA approval of three amyloid tracers, and the failure of a number of recent therapeutic trials conducted in the early dementia phase. On the one hand, an early etiological diagnosis can lead to early and more efficacious intervention. On the other hand, it (...)
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  • Using practical wisdom to facilitate ethical decision-making: a major empirical study of phronesis in the decision narratives of doctors.Chris Turner, Alan Brockie, Catherine Weir, Catherine Hale, Aisha Y. Malik & Mervyn Conroy - 2021 - BMC Medical Ethics 22 (1):1-13.
    BackgroundMedical ethics has recently seen a drive away from multiple prescriptive approaches, where physicians are inundated with guidelines and principles, towards alternative, less deontological perspectives. This represents a clear call for theory building that does not produce more guidelines. Phronesis (practical wisdom) offers an alternative approach for ethical decision-making based on an application of accumulated wisdom gained through previous practice dilemmas and decisions experienced by practitioners. Phronesis, as an ‘executive virtue’, offers a way to navigate the practice virtues for any (...)
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  • What ethical resources are available to Alcohol and Other Drug practitioners? A systematic review.David Silkoff, Marilys Guillemin, Richard Chenhall & Rosalind McDougall - 2018 - Clinical Ethics 13 (1):34-52.
    Clinical work in Alcohol and Other Drugs has not generally been an area of focus for ethicists. Likewise, ethics is not usually part of Alcohol and Other Drugs training or practice. This means that resources available to Alcohol and Other Drugs clinicians navigating ethical challenges are not widely available. This paper describes a systematic review of literature at the intersection of ethics and clinical practice in Alcohol and Other Drugs. The review will potentially benefit Alcohol and Other Drug practitioners by (...)
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  • Ethical understandings of proxy decision making for research involving adults lacking capacity: A systematic review (framework synthesis) of empirical research.Victoria Shepherd, Kerenza Hood, Mark Sheehan, Richard Griffith, Amber Jordan & Fiona Wood - 2018 - AJOB Empirical Bioethics 9 (4):267-286.
    Background: Research involving adults lacking mental capacity relies on the involvement of a proxy or surrogate, although this raises a number of ethical concerns. Empirical studies have examined attitudes towards proxy decision-making, proxies’ authority as decision-makers, decision accuracy, and other relevant factors. However, a comprehensive evidence-based account of proxy decision-making is lacking. This systematic review provides a synthesis of the empirical data reporting the ethical issues surrounding decisions made by research proxies, and the development of a conceptual framework of proxy (...)
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  • Instrumentalist analyses of the functions of ethics concept-principles: a proposal for synergetic empirical and conceptual enrichment.Eric Racine, M. Ariel Cascio, Marjorie Montreuil & Aline Bogossian - 2019 - Theoretical Medicine and Bioethics 40 (4):253-278.
    Bioethics has made a compelling case for the role of experience and empirical research in ethics. This may explain why the movement for empirical ethics has such a firm grounding in bioethics. However, the theoretical framework according to which empirical research contributes to ethics—and the specific role it can or should play—remains manifold and unclear. In this paper, we build from pragmatic theory stressing the importance of experience and outcomes in establishing the meaning of ethics concepts. We then propose three (...)
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  • A systematic review of the literature on ethical aspects of transitional care between child- and adult-orientated health services.Moli Paul, Lesley O’Hara, Priya Tah, Cathy Street, Athanasios Maras, Diane Purper Ouakil, Paramala Santosh, Giulia Signorini, Swaran Preet Singh, Helena Tuomainen & Fiona McNicholas - 2018 - BMC Medical Ethics 19 (1):73.
    Healthcare policy and academic literature have promoted improving the transitional care of young people leaving child and adolescent mental health services. Despite the availability of guidance on good practice, there seems to be no readily accessible, coherent ethical analysis of transition. The ethical principles of non-maleficence, beneficence, justice and respect for autonomy can be used to justify the need for further enquiry into the ethical pros and cons of this drive to improve transitional care. The objective of this systematic review (...)
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  • How to tackle the conundrum of quality appraisal in systematic reviews of normative literature/information? Analysing the problems of three possible strategies.Marcel Mertz - 2019 - BMC Medical Ethics 20 (1):1-12.
    Background In the last years, there has been an increase in publication of systematic reviews of normative literature or of normative information in bioethics. The aim of a systematic review is to search, select, analyse and synthesise literature in a transparent and systematic way in order to provide a comprehensive and unbiased overview of the information sought, predominantly as a basis for informed decision-making in health care. Traditionally, one part of the procedure when conducting a systematic review is an appraisal (...)
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  • Deliberative Clinical Ethics: Getting Back to Basics in the Work of Clinical Ethics and Clinical Ethicists.Laurence B. McCullough - 2014 - Journal of Medicine and Philosophy 39 (1):1-7.
    The six papers in the 2014 clinical ethics number of the Journal get us back to the basics in the work of clinical ethics and clinical ethicists: getting clear about concepts that should be used in achieving deliberative clinical ethics. The papers explore the concepts of the best interests of the patient, health and disease understood in their proper relationship to autonomy in our species, the therapeutic obligation, and the therapeutic imperative. The final paper appraises the systematic review, a scholarly (...)
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  • Relational autonomy: what does it mean and how is it used in end-of-life care? A systematic review of argument-based ethics literature.Carlos Gómez-Vírseda, Yves de Maeseneer & Chris Gastmans - 2019 - BMC Medical Ethics 20 (1):1-15.
    BackgroundRespect for autonomy is a key concept in contemporary bioethics and end-of-life ethics in particular. Despite this status, an individualistic interpretation of autonomy is being challenged from the perspective of different theoretical traditions. Many authors claim that the principle of respect for autonomy needs to be reconceptualised starting from a relational viewpoint. Along these lines, the notion of relational autonomy is attracting increasing attention in medical ethics. Yet, others argue that relational autonomy needs further clarification in order to be adequately (...)
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  • The concept of vulnerability in aged care: a systematic review of argument-based ethics literature.Chris Gastmans, Roberta Sala & Virginia Sanchini - 2022 - BMC Medical Ethics 23 (1):1-20.
    BackgroundVulnerability is a key concept in traditional and contemporary bioethics. In the philosophical literature, vulnerability is understood not only to be an ontological condition of humanity, but also to be a consequence of contingent factors. Within bioethics debates, vulnerable populations are defined in relation to compromised capacity to consent, increased susceptibility to harm, and/or exploitation. Although vulnerability has historically been associated with older adults, to date, no comprehensive or systematic work exists on the meaning of their vulnerability. To fill this (...)
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  • Core aspects of ubuntu: A systematic review.C. Ewuoso & S. Hall - 2019 - South African Journal of Bioethics and Law 12 (2):93.
  • Ethical Challenges Experienced by Healthcare Workers Delivering Clinical Care during Health Emergencies and Disasters: A Rapid Review of Qualitative Studies and Thematic Synthesis.Mariana Dittborn, Constanza Micolich, Daniela Rojas & Sofía P. Salas - 2022 - AJOB Empirical Bioethics 13 (3):179-195.
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  • Among equity and dignity: an argument-based review of European ethical guidelines under COVID-19.Ludovica De Panfilis & Marta Perin - 2021 - BMC Medical Ethics 22 (1):1-29.
    BackgroundUnder COVID-19 pandemic, many organizations developed guidelines to deal with the ethical aspects of resources allocation. This study describes the results of an argument-based review of ethical guidelines developed at the European level. It aims to increase knowledge and awareness about the moral relevance of the outbreak, especially as regards the balance of equity and dignity in clinical practice and patient’s care. MethodAccording to the argument-based review framework, we started our research from the following two questions: what are the ethical (...)
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  • A systematic review of empirical bioethics methodologies.Rachel Davies, Jonathan C. S. Ives & Michael Dunn - 2015 - BMC Medical Ethics 16 (1):15.
    Despite the increased prevalence of bioethics research that seeks to use empirical data to answer normative research questions, there is no consensus as to what an appropriate methodology for this would be. This review aims to search the literature, present and critically discuss published Empirical Bioethics methodologies.
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