What do we quantify when we attempt to quantify semiotic systems and theories? How sound are potential quantifications in terms of interpretive values within some varieties of semiotic theory? We will make a distinction between formalization and quantification in order to understand what to quantify, how to quantify it and why quantification may be a desirable outcome for semiotic theory. The implications of this stance may be relevant and philosophically interesting in light of the naturalized project of biosemiotics. In this (...) paper we will try to understand some ideas behind the rationale of formalizing and quantifying semiotic phenomena and discuss whether this possibility can or should map to functionalized descriptions of semiosis and the sign. (shrink)