In this paper I consider a cluster of positions which depart from the immortalist and dualist anthropologies of Rene Descartes and Henry More. In particular, I argue that John Locke and Isaac Newton are attracted to a monistic mind-body metaphysics, which while resisting neat characterization, occupies a conceptual space distinct from the dualism of the immortalists, on the one hand, and thoroughgoing materialism of Thomas Hobbes, on the other. They propound a sort of property monism: mind and body are distinct, (...) with distinct characteristics and functions, but are, nevertheless, ontologically interdependent. Consciousness ? the locus of personhood, and thus, a necessary condition for personal immortality ? is an embodied phenomenon; its preservation requires the life and proper functioning of the body. Dying with the dissolution of his body, then, man is a compound wholly mortal. Nevertheless, both Locke and Newton accepted the possibility of personal immortality; with Hobbes, both looked to the Biblical promise of bodily resurrection. For with the re-vitalization of the body ? and a subsequent restoration of consciousness and memory ? personal identity is preserved, even beyond the grave. (shrink)