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  1. Chimeras Intended for Human Gamete Production: An Ethical Alternative?César Palacios-González - 2017 - Reproductive Biomedicine Online 35 (4):387-390.
    Human eggs for basic, fertility and stem-cell research are in short supply. Many experiments that require their use cannot be carried out at present, and, therefore, the benefits that could emerge from these are either delayed or never materialise. This state of affairs is problematic for scientists and patients worldwide, and it is a matter that needs our attention. Recent advances in chimera research have opened the possibility of creating human/non-human animal chimeras intended for human gamete production (chimeras-IHGP). In this (...)
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  • A Framework for the Ethical Assessment of Chimeric Animal Research Involving Human Neural Tissue.Sebastian Porsdam Mann, Rosa Sun & Göran Hermerén - 2019 - BMC Medical Ethics 20 (1):10.
    Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological disorders difficult to study in humans, chimeric models with human neural tissue could help advance our understanding of neuropathophysiology. In (...)
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  • The Ethics of Killing Human/Great-Ape Chimeras for Their Organs: A Reply to Shaw Et Al.César Palacios-González - 2016 - Medicine, Health Care and Philosophy 19 (2):215-225.
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