This paper revisits the epistemological doctrine of fallibilism and discusses its overarching consequences to the whole structure of human knowledge and its extended applications. Fallibilism claims that we can never have absolute certainty to justify our knowledge claims. That means, knowledge needs not have an absolute, definitive warrants. Consequently, using the discursive method of enquiry, the paper argues that, if fallibilism is true, then, the concept of knowledge is redefined. Hence, knowledge would no longer mean the preclusion of error but (...) the contextual absence of doubt. Accordingly, knowledge in this schema, would only be an approximation [or even a verisimilitude] to the truth or a working tool for future progress so long as it serves the purposes of the present. It is the conclusion of the paper, that aside its apparent epistemic implications, fallibilism has also non-epistemic implications which ranges from a more general change in attitude towards our stances to a more applied and direct consequences in both legal, religious or moral enterprises of human endeavours. (shrink)