This book on Philosophy of Science includes a comprehensive discussion of ontology, epistemology, and axiology of science in the constellation of various other knowledge, as well as the development of scientific knowledge holistically contained in each module in this course. These three things are branches of philosophy which are very useful for students of Teacher Training and Education in mediating the learning and learning process so that the essence of Philosophy of Science can then be implemented within the scope of (...) professionalism in particular and society in general and the challenges of the industrial era 4.0 in the 20th century 21 The discussion on ontology is focused on elements of empirical reality (empericism) such as facts, data, and information without releasing it from rational reality (rationalism), and its position in scientific activities. The epistemology of science is focused on the scientific method and its operationalization in research methodology. The axiology of science discusses the values ​​associated with scientific activities and their uses, both internally, externally, and socially. (shrink)