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  1. Two models of models in biomedical research.Hugh LaFollette & Niall Shanks - 1995 - Philosophical Quarterly 45 (179):141-160.
    Biomedical researchers claim there is significant biomedical information about humans which can be discovered only through experiments on intact animal systems (AMA p. 2). Although epidemiological studies, computer simulations, clinical investigation, and cell and tissue cultures have become important weapons in the biomedical scientists' arsenal, these are primarily "adjuncts to the use of animals in research" (Sigma Xi p. 76). Controlled laboratory experiments are the core of the scientific enterprise. Biomedical researchers claim these should be conducted on intact biological systems, (...)
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  • Animal pain.Colin Allen - 2004 - Noûs 38 (4):617-643.
    Which nonhuman animals experience conscious pain?1 This question is central to the debate about animal welfare, as well as being of basic interest to scientists and philosophers of mind. Nociception—the capacity to sense noxious stimuli—is one of the most primitive sensory capacities. Neurons functionally specialized for nociception have been described in invertebrates such as the leech Hirudo medicinalis and the marine snail Aplysia californica (Walters 1996). Is all nociception accompanied by conscious pain, even in relatively primitive animals such as Aplysia, (...)
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  • Helping doctors become better doctors: Mary Lobjoit—an unsung heroine of medical ethics in the UK.Margaret R. Brazier, Raanan Gillon & John Harris - 2012 - Journal of Medical Ethics 38 (6):383-385.
    Medical Ethics has many unsung heros and heroines. Here we celebrate one of these and on telling part of her story hope to place modern medical ethics and bioethics in the UK more centrally within its historical and human contex.
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  • On balance: weighing harms and benefits in fundamental neurological research using nonhuman primates.Gardar Arnason & Jens Clausen - 2016 - Medicine, Health Care and Philosophy 19 (2):229-237.
    One of the most controversial areas of animal research is the use of nonhuman primates for fundamental research. At the centre of the controversy is the question of whether the benefits of research outweigh the harms. We argue that the evaluation of harms and benefits is highly problematic. We describe some common procedures in neurological research using nonhuman primates and the difficulties in evaluating the harm involved. Even if the harm could be quantified, it is unlikely that it could be (...)
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  • Multi-cellular engineered living systems: building a community around responsible research on emergence.Matthew Sample, Marion Boulicault, Caley Allen, Rashid Bashir, Insoo Hyun, Megan Levis, Caroline Lowenthal, David Mertz & Nuria Montserrat - 2019 - Biofabrication 11 (4).
    Ranging from miniaturized biological robots to organoids, multi-cellular engineered living systems (M-CELS) pose complex ethical and societal challenges. Some of these challenges, such as how to best distribute risks and benefits, are likely to arise in the development of any new technology. Other challenges arise specifically because of the particular characteristics of M-CELS. For example, as an engineered living system becomes increasingly complex, it may provoke societal debate about its moral considerability, perhaps necessitating protection from harm or recognition of positive (...)
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  • How Should We Study Animal Consciousness Scientifically?Jonathan Birch, Donald M. Broom, Heather Browning, Andrew Crump, Simona Ginsburg, Marta Halina, David Harrison, Eva Jablonka, Andrew Y. Lee, François Kammerer, Colin Klein, Victor Lamme, Matthias Michel, Françoise Wemelsfelder & Oryan Zacks - 2022 - Journal of Consciousness Studies 29 (3-4):8-28.
    This editorial introduces the Journal of Consciousness Studies special issue on "Animal Consciousness". The 15 contributors and co-editors answer the question "How should we study animal consciousness scientifically?" in 500 words or fewer.
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  • Animal Consciousness: The Interplay of Neural and Behavioural Evidence.Andrew Crump & Jonathan Birch - 2022 - Journal of Consciousness Studies 29 (3-4):104-128.
    We consider the relationship between neural and behavioural evidence for animal consciousness. We critically examine two recent studies: one neural and one behavioural. The first, on crows, finds different neural activity depending on whether a stimulus is reported as seen or unseen. However, to implicate this neural activity in consciousness, we must assume that a specific conditioned behaviour is a report of conscious experience. The second study, on macaques, records behaviours strikingly similar to patterns of conscious and unconscious perception in (...)
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