Human nature is something of a taboo on the left wing of contemporary political theory and scarcely more than a commonsense assumption on its right wing. This article aims to expose the taboo and to challenge the assumption. There is no way, we argue, to defeat conservative political theory without delving into political anthropology. With this purpose in mind, our article analyses the writings of Marx and Engels, and Simondon’s concepts of the transindividual and technics. It shows that Simondon’s theory (...) of technics allows new interpretations of many of the themes scattered in Marx’s and Engels’s works and helps to formulate a materialist political anthropology which entails a political project of liberating ‘human nature’ _from_ labour. (shrink)