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Toward a mechanistic Evo Devo

In Manfred Laubichler & Jane Maienschein (eds.), Form and Function in Developmental Evolution. Cambridge University Press. pp. 213 (2009)

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  1. Typology and Natural Kinds in Evo-Devo.Ingo Brigandt - 2021 - In Nuño De La Rosa Laura & Müller Gerd (eds.), Evolutionary Developmental Biology: A Reference Guide. Springer. pp. 483-493.
    The traditional practice of establishing morphological types and investigating morphological organization has found new support from evolutionary developmental biology (evo-devo), especially with respect to the notion of body plans. Despite recurring claims that typology is at odds with evolutionary thinking, evo-devo offers mechanistic explanations of the evolutionary origin, transformation, and evolvability of morphological organization. In parallel, philosophers have developed non-essentialist conceptions of natural kinds that permit kinds to exhibit variation and undergo change. This not only facilitates a construal of species (...)
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  • Explanation in Evo-Devo.Marie I. Kaiser - 2021 - In de la Rosa L. N. & Müller G. B. (eds.), Evolutionary Developmental Biology - A Reference Guide. Springer.
    Evo-devo is a multidisciplinary field that investigates the interplay between evolutionary and developmental processes and brings together different kinds of explanatory strategies. This chapter examines the structure of paradigmatic explanations in evo-devo (e.g., the explanation of the origin of an evolutionary novelty) and raises philosophical questions about explanation in evo-devo. Much research in evo-devo is concerned with studying the developmental mechanisms that constrain and facilitate phenotypic evolution, which suggests that a distinctive feature of evo-devo is that it constructs mechanistic explanations. (...)
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  • Rethinking Causation in Cancer with Evolutionary Developmental Biology.Katherine E. Liu - 2017 - Biological Theory 13 (4):228-242.
    Despite the productivity of basic cancer research, cancer continues to be a health burden to society because this research has not yielded corresponding clinical applications. Many proposed solutions to this dilemma have revolved around implementing organizational and policy changes related to cancer research. Here I argue for a different solution: a new conceptualization of causation in cancer. Neither the standard molecular biomarker approaches nor evolutionary biology approaches to cancer fully capture its complex causal dynamics, even when considered jointly. These approaches (...)
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