Skip to main content
Log in

From the Triple Helix to a Quadruple Helix? The Case of Dip-Pen Nanolithography

  • Published:
Minerva Aims and scope Submit manuscript

Abstract

In this article, we propose four modifications to the standard Triple Helix innovation model, which consists of the three strands: university, government, industry. First, in view of recent economic, cultural, organizational and ideological changes in many countries, it is now important to introduce a fourth strand to the standard model, namely society. Second, we observe that strands occur in doublets which we refer to as binomials. Examples of doublets include university/society, university/industry, industry/society, etc. Third, the binomials are organized in a hierarchic mode; for example in the university/society binomial, university may be dominant and the society secondary. The hierarchy arrangement proves decisive. Fourth, Helix-driven innovation processes take the form of temporary segmented phases. Using the case study of Dip-Pen nanolithography, we identify four phases where each phase is characterised by specific binomials accompanied by a hierarchy: academic instrument research (university/society); from instrument to tool; company start-up (university/industry); the mature firm and commercialization (industry/society); confirming the societal strand “nanofication”(society/industry). The government strand operates as a recessive component in phases one and four.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Notes

  1. Other attempts have been made to extend the Triple Helix into a Quadruple Helix (Leydesdorff and Etzkowitz 2003, Etzkowitz and Zhou 2007, Etzkowitz 2008).

  2. During the fourth stage, numerous other initiatives were taken which will not be presented in this text. For further information on these developments, see Marcovich and Shinn (2011).

  3. While the Dip-Pen proper was at this phase characterized by relative simplicity, the AFM on which it depends itself constitutes a highly complex device, because of its electronic and computational environment.

  4. C. Mirkin et al., “Methods Utilizing Scanning Probe Microscope Tips and Products Thereof or Produced Thereby”, United States Patent 7,446,324, November 4, 2008.

  5. Dr. Calvin F. Quate was one of the fathers of the AFM invented in 1986.

  6. http://www.nanoink.net/NSCRIPTOR.htm (11.3.2009).

  7. http://www.nanoink.net/d/technote_inkcal_software.pdf (11.3.2009).

  8. Interview September 11, 2009 of T. Levesque with authors.

  9. http://www.nanoink.net/d/appnote_JustAddDNA.pdf (11.3.2009).

  10. http://www.nanoink.net/NanoStem_about.htm (20.9.2009).

  11. Interview of Tom Levesque February 22, 2009 with authors. Student-writing manual for NanoInk: “A Basic Protocol for the NanoLithography Platform”, Ben Wilcox, NanoInk Inc., Summer 2008, 18p.

  12. http://nanobusiness.org/index.php (consulted April 1, 2010).

  13. Nano-oriented pedagogical reform is likewise growing outside the United States. Australia is developing a national educational program in nanoscience and technology directed at the secondary level. Like the I-tist program at Philadelphia it is designed to establish convergence between biology, chemistry and physics, to introduce students to learning in nano, to demonstrate nano’s affinity for applications and to inform youth about growing nano-related career openings (http://www.accessnano.org/about). The Netherlands are completing plans to introduce nano as one optional module in secondary school science teaching. Again nano will point to parallels between biology, chemistry and physics (Letter from Florine Meijer, project coordinator of nano instruction documentation University of Utrecht, Netherlands, to author, April 9. 2010). It would seem that among pedagogical reformers great attention is today being given to transversalities between disciplines. Finally, the European Union now too promotes educational programs in nano. These are directed at the bachelor, masters and doctoral level, with an eye to career potential in corporate technology (Malsch 2008).

References

  • Etzkowitz, Henry, and Loet Leydesdorff. 1995. The Triple Helix—University-Industry-Government Relations: A Laboratory for Knowledge-Based Economic Development. EASST Review 14(1): 14–19.

    Google Scholar 

  • Etzkowitz, Henry, and Loet Leydesdorff. 2000. The dynamics of innovation: from National Systems and ‘‘Mode 2’’ to a Triple Helix of university–industry–government relations. Research Policy 29: 109–123.

    Article  Google Scholar 

  • Etzkowitz, Henry. 2008. The Triple Helix: University-Industry-Government Innovation in Action. London: Routledge.

    Book  Google Scholar 

  • Etzkowitz, Henry, and C Zhou. 2007. Regional Innovation Initiator: the entrepreneurial University in various Triple Helix Moldels. Singapore Triple Helix VI Conference. Conference Theme Paper (http://nus.edu/nec/eir/TripleHelix6/SingaporeConferenceThemePaper050107.pdf).

  • Feynman, Richard. 1960. There is plenty of room at the bottom, Engineering and Science Available on the web http://www.zyvex.com/nanotech/feynman.html.

  • Forman, Paul. 1987. Behind quantum electronics: National security as basis for physical research in the United States, 1940–1960. Historical Studies in the Physical and Biological Sciences 18(Pt. 1): 149–229.

    Google Scholar 

  • Leydesdorff, Loet, and Henry Etzkowitz. 1997. Universities and the Global Knowledge Economy : a Triple Helix of University-Industry-Government Relations.

  • Leydesdorff, Loet, and Henry Etkowitz. 2003. Can "The Public" be considered as a fourth Helix in University-Industry-Government Relation? Report on the fourth Triple Helix Conference 2002. Science and Public Policy 30(1): 77–83.

  • LightFeather, J AF LightFeather, Judith ED Lakhtakia, A; Maksimenko, SA. 2006. “Immersive virtual learning environments for nano science education: A paradigm shift”—art. no. 63280 Nanomodeling II Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE) CT Conference on Nanomodeling II CY AUG 13-15 CL San Diego, CA.

  • Luhmann, Niklas. 1995. Social Systems. University Press: Stanford.

    Google Scholar 

  • Mac Cray, William Patrick. 2005. Will Small be Beautiful? Making Policies for our Nanotech Future. History and Technology 21(2): 177–203.

    Article  Google Scholar 

  • Mac Cray, William Patrick. 2009. From Lab to iPod: A Story of Discovery and commercialization in the Post–Cold War Era Technology and Culture. Technology and Culture 50(1): 57–81.

    Google Scholar 

  • Malsch, Ineke. 2008. Nano-education from a European perspective, Malsch TechnoValuation Vondellaan 90 3521 GH Utrecht, The Netherlands. Journal of Physics: Conference Series 100.

  • Marcovich, Anne, and Terry Shinn. 2011. Instrument Research, Tools and the Knowledge Enterprise 1999–2009 Birth and Development of Dip-Pen Nanolithography. Science, Technology, and Human Values (forthcoming).

  • Mody, Cyrus. 2006. Corporations, Universities, and Instrumental Communities: Commercializing Probe Microscopy, 1981–1996. Technology and Culture 47: 56–80.

    Article  Google Scholar 

  • Rebentrost, Inken. 2006. Das Labor in der Box. Technikentwicklung und Unternehmensgründung in der Frühen Deutschen Biotechnologie, Schriftenreihe zur Zeitschrift für Unternehmensgeschichte, Verlag C.H. Beck, Band 16.

  • Richard, D. Piner, Jin Zhu, Xu Feng, Seunghun Hong, and Chad A. Mirkin. 1999. Dip-Pen nanolithography. Science 283(5402): 661–663.

    Article  Google Scholar 

  • Shinn, Terry. 2002. The triple helix and new production of knowledge: prepackaged thinking on science and technology. Social Studies of Science 32(4): 599–614.

    Google Scholar 

  • Thune, Taran. 2010. The training of “triple helix workers”? Doctoral Students in University–Industry–Government Collaborations. Minerva 48(4): 463–483.

    Article  Google Scholar 

Download references

Acknowledgements

We wish to thank Tom Levesque who was at the time of our research vice-president of NanoInk Inc. Fabrication division for the information that he generously provided. We are also indebted to Maria Caramez Carlotto (University of Sao Paolo) for recommending transformations to an earlier draft of this text.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Anne Marcovich.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marcovich, A., Shinn, T. From the Triple Helix to a Quadruple Helix? The Case of Dip-Pen Nanolithography. Minerva 49, 175–190 (2011). https://doi.org/10.1007/s11024-011-9169-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11024-011-9169-z

Keywords

Navigation