Medial Temporal Lobe Roles in Human Path Integration
Naohide
Yamamoto1, 2*,
John
Philbeck2, 3,
Adam
Woods2, 4,
Daniel
Gajewski2,
Joeanna
Arthur2, 5,
Samuel
Potolicchio6,
Lucien
Levy7 and
Anthony
Caputy8
-
1
Cleveland State University, Department of Psychology, United States
-
2
The George Washington University, Department of Psychology, United States
-
3
University of Wollongong, School of Psychology, Australia
-
4
University of Florida, Cognitive Aging and Memory Clinical Translational Research Program, Institute on Aging, United States
-
5
National Geospatial-Intelligence Agency, Office of Basic & Applied Research, United States
-
6
The George Washington University, Department of Neurology, United States
-
7
The George Washington University, Department of Radiology, United States
-
8
The George Washington University, Department of Neurological Surgery, United States
Path integration is a process in which observers derive their location by integrating self-motion signals along their locomotion trajectory. Although the medial temporal lobe (MTL) is thought to take part in path integration, the scope of its role for path integration remains unclear. To address this issue, we administered a variety of tasks involving path integration and other related processes to a group of neurosurgical patients whose MTL was unilaterally resected as therapy for epilepsy. These patients were unimpaired relative to neurologically intact controls in many tasks that required integration of various kinds of sensory self-motion information. However, the same patients (especially those who had lesions in the right hemisphere) walked farther than the controls when attempting to walk without vision to a previewed target. Importantly, this task was unique in our test battery in that it allowed participants to form a mental representation of the target location and anticipate their upcoming walking trajectory before they began moving. Thus, these results put forth a new idea that the role of MTL structures for human path integration may stem from their participation in predicting the consequences of one's locomotor actions.
Keywords:
Epilepsy,
Locomotion,
self-motion,
temporal lobectomy
Conference:
XII International Conference on Cognitive Neuroscience (ICON-XII), Brisbane, Queensland, Australia, 27 Jul - 31 Jul, 2014.
Presentation Type:
Poster
Topic:
Sensation and Perception
Citation:
Yamamoto
N,
Philbeck
J,
Woods
A,
Gajewski
D,
Arthur
J,
Potolicchio
S,
Levy
L and
Caputy
A
(2015). Medial Temporal Lobe Roles in Human Path Integration.
Conference Abstract:
XII International Conference on Cognitive Neuroscience (ICON-XII).
doi: 10.3389/conf.fnhum.2015.217.00389
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Received:
19 Feb 2015;
Published Online:
24 Apr 2015.
*
Correspondence:
Dr. Naohide Yamamoto, Cleveland State University, Department of Psychology, Cleveland, United States, yamamoto@jhu.edu