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Correction and use of biomedical literature affected by scientific misconduct

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Abstract

The purpose of this study was to identify and describe published research articles that were named in official findings of scientific misconduct and to investigate compliance with the administrative actions contained in these reports for corrections and retractions, as represented in PubMed. Between 1993 and 2001, 102 articles were named in either the NIH Guide for Grants and Contracts (“Findings of Scientific Misconduct”) or the U.S. Office of Research Integrity annual reports as needing retraction or correction. In 2002, 98 of the 102 articles were indexed in PubMed. Eighty-five of these 98 articles had indexed corrections: 47 were retracted; 26 had an erratum; 12 had a correction described in the “comment” field. Thirteen had no correction, but 10 were linked to the NIH Guide “Findings of Scientific Misconduct”, leaving only 3 articles with no indication of any sort of problem. As of May 2005, there were 5,393 citations to the 102 articles, with a median of 26 citations per article (range 0–592). Researchers should be alert to “Comments” linked to the NIH Guide as these are open access, and the “Findings of Scientific Misconduct’ reports are often more informative than the statements about the retraction or correction found in the journals.

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Notes

  1. Before 1986, reports of scientific misconduct were received by funding institutes within the PHS agencies. Attempts to create a central locus for scientific misconduct lead to the formation of the Institutional Liaison Office. In 1989, the Public Health Service created the Office of Scientific Integrity (OSI) in the Office of the Director, National Institutes of Health, and the Office of Scientific Integrity Review (OSIR) in the Office of the Assistant Secretary for Health (OASH), for the sole purpose of dealing with scientific misconduct. In 1992, the offices were combined to form the Office of Research Integrity (ORI) in the OASH. In 1993, the ORI was established as an independent entity within the Department of Health and Human Services (HHS). Organizationally, the ORI is located within the Office of the Secretary of HHS in the Office of Public Health and Science which is headed by the Assistant Secretary for Health. [15]

  2. A finding of scientific misconduct requires that: (a) there be a significant departure from accepted practices of the relevant research community; and (b) the misconduct be committed intentionally, or knowingly, or recklessly; and (c) the allegation be proven by a preponderance of evidence [16].

  3. Usually a small piece of paper (e.g. 5′′ × 8′′ approximately) inserted into the journal to report an erratum or retraction that is not bound into the permanent journal issue.

  4. In some cases, the finding of misconduct was published years after an affected article was published, and the report indicated that a retraction or correction had already been posted.

  5. In some cases, the finding of misconduct was published years after an affected article was published, and the report indicated that a retraction or correction had already been posted.

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Acknowledgments

This research was supported by the Research on Research Integrity Program, an ORI/NIH collaboration, grant # R01 NS44487.

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Corresponding author

Correspondence to Anne Victoria Neale.

Appendix

Appendix

Bibliography of 102 articles identified in final reports of “Findings of Scientific Misconduct” (from either the NIH Guide for Grants and Contracts or the Office of Research Integrity Annual Reports 1993–2001). Respondents named in these findings of scientific misconduct are in bold

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A33.

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A39.

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A40.

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A41.

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  1. *  The person named as responsible for the scientific misconduct (the respondent) was not a co-author on this paper

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Neale, A.V., Northrup, J., Dailey, R. et al. Correction and use of biomedical literature affected by scientific misconduct . SCI ENG ETHICS 13, 5–24 (2007). https://doi.org/10.1007/s11948-006-0003-1

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