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Schizophrenia-related phenomena that challenge prediction error as the basis of cognitive functioning

Published online by Cambridge University Press:  10 May 2013

Steven M. Silverstein*
Affiliation:
University Behavioral HealthCare and Department of Psychiatry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08854. silvers1@umdnj.edu

Abstract

There are aspects of schizophrenia that pose challenges for Clark's model. These include: (1) evidence for excitatory activity underlying self-organizing neural ensembles that support coordinating functions, and their impairment in schizophrenia; (2) evidence regarding hallucinations that suggest they are not due to excessive prediction error; and (3) the critical role of emotional factors as setting conditions for delusion formation.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2013 

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