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Behavior genetics: Causality as a dialectical pursuit

Published online by Cambridge University Press:  11 September 2023

Livio Tarchi
Affiliation:
Psychiatry Unit, Department of Health Sciences, University of Florence, Florence, FI, Italy livio.tarchi@unifi.it giuseppepierpaolo.merola@unifi.it giovanni.castellini@unifi.it valdo.ricca@unifi.it
Giuseppe Pierpaolo Merola
Affiliation:
Psychiatry Unit, Department of Health Sciences, University of Florence, Florence, FI, Italy livio.tarchi@unifi.it giuseppepierpaolo.merola@unifi.it giovanni.castellini@unifi.it valdo.ricca@unifi.it
Giovanni Castellini
Affiliation:
Psychiatry Unit, Department of Health Sciences, University of Florence, Florence, FI, Italy livio.tarchi@unifi.it giuseppepierpaolo.merola@unifi.it giovanni.castellini@unifi.it valdo.ricca@unifi.it
Valdo Ricca
Affiliation:
Psychiatry Unit, Department of Health Sciences, University of Florence, Florence, FI, Italy livio.tarchi@unifi.it giuseppepierpaolo.merola@unifi.it giovanni.castellini@unifi.it valdo.ricca@unifi.it

Abstract

The overarching theme of causality in behavioral genetics is discussed on epistemological grounds. Evidence is offered in favor of a continuum spectrum in causality, in contrast to discrimination between causal factors and associations. The risk of invalidating exploratory studies in behavior genetics is discussed, especially for the potential impact on those fields of medicine interested in complex behaviors.

Type
Open Peer Commentary
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press

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References

Baumgartner, M. (2008). Regularity theories reassessed. Philosophia, 36(3), 327354. https://doi.org/10.1007/s11406-007-9114-4CrossRefGoogle Scholar
Baumgartner, M., & Ambühl, M. (2020). Causal modeling with multi-value and fuzzy-set coincidence analysis. Political Science Research and Methods, 8(3), 526542. https://doi.org/10.1017/psrm.2018.45CrossRefGoogle Scholar
Benesty, J., Chen, J., Huang, Y., & Cohen, I. (2009). Pearson correlation coefficient. In Cohen, I., Huang, Y., Chen, J., & Benesty, J. (Eds.), Noise reduction in speech processing (pp. 14). Springer. https://doi.org/10.1007/978-3-642-00296-0_5Google Scholar
Bulik, C. M. (2021). From awareness to action: An urgent call to address the inadequacy of treatment for anorexia nervosa. American Journal of Psychiatry, 178(9), 786788. https://doi.org/10.1176/appi.ajp.2021.21070697CrossRefGoogle ScholarPubMed
Kendler, K. S., & Neale, M. C. (2010). Endophenotype: A conceptual analysis. Molecular Psychiatry, 15(8), 789797. https://doi.org/10.1038/mp.2010.8CrossRefGoogle ScholarPubMed
Mitchell, J. E., Maki, D. D., Adson, D. E., Ruskin, B. S., & Crow, S. (1997). The selectivity of inclusion and exclusion criteria in bulimia nervosa treatment studies. International Journal of Eating Disorders, 22(3), 243252. https://doi.org/10.1002/(SICI)1098-108X(199711)22:3<243::AID-EAT3>3.0.CO;2-N3.0.CO;2-N>CrossRefGoogle ScholarPubMed
Popper, K. R. (1940). What is dialectic? Mind; A Quarterly Review of Psychology and Philosophy, XLIX(194), 403426. https://doi.org/10.1093/mind/XLIX.194.403CrossRefGoogle Scholar
Rosenberg, M. D., & Finn, E. S. (2022). How to establish robust brain–behavior relationships without thousands of individuals. Nature Neuroscience, 25(7), 835837. https://doi.org/10.1038/s41593-022-01110-9CrossRefGoogle ScholarPubMed
Sirugo, G., Williams, S. M., & Tishkoff, S. A. (2019). The missing diversity in human genetic studies. Cell, 177(1), 2631. https://doi.org/10.1016/j.cell.2019.02.048CrossRefGoogle ScholarPubMed
Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012). Five years of GWAS discovery. The American Journal of Human Genetics, 90(1), 724. https://doi.org/10.1016/j.ajhg.2011.11.029CrossRefGoogle ScholarPubMed
Wang, J., Veugelers, R., & Stephan, P. (2017). Bias against novelty in science: A cautionary tale for users of bibliometric indicators. Research Policy, 46(8), 14161436. https://doi.org/10.1016/j.respol.2017.06.006CrossRefGoogle Scholar