Rewiring the damaged-pathway through BCI restore volitional control paretic limb
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1
National Institute for Physiological Sciences, Department of Behavioral Development, Japan
Paretic Individuals really longs for regaining their impaired function using their own limbs. One possible avenue to achieve this goal is artificial neural connection which wires the preserved neural structures to bridge the interrupted pathway through brain computer interface. I will show an artificial neuronal connection that bridges supra-spinal system and spinal network beyond the lesion site restores lost function. The artificial connection was produced by a brain computer interface that can detect the neural activity and converted in real-time to activity-contingent stimuli delivered to nervous system. A promising application is to bridge impaired biological connections, as demonstrated for volitionally-controlled stimulation to a residual system. Here we demonstrate that monkeys with subcortical stroke had adequate adaptability to harness artificial connection which is brain-controlled functional electrical stimulation to paretic muscles. Adaptation to artificial connection was flexibly achieved by modulating oscillatory brain activity among extensive cortical areas. Recent work has shown that volitional walking in individuals with severe spinal cord injury can be restored by muscle-controlled magnetic stimulation to lumbar spinal cord. These results suggest that artificial neural connections can compensate for interrupted descending pathways and restores volitional control paretic limb.
Conference:
2015 International Workshop on Clinical Brain-Machine Interfaces (CBMI2015), Tokyo, Japan, 13 Mar - 15 Mar, 2015.
Presentation Type:
Oral presentation / lecture
Topic:
Clinical Brain-Machine Interfaces
Citation:
Nishimura
Y
(2015). Rewiring the damaged-pathway through BCI restore volitional control paretic limb.
Conference Abstract:
2015 International Workshop on Clinical Brain-Machine Interfaces (CBMI2015).
doi: 10.3389/conf.fnhum.2015.218.00009
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Received:
23 Apr 2015;
Published Online:
29 Apr 2015.
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Correspondence:
PhD. Yukio Nishimura, National Institute for Physiological Sciences, Department of Behavioral Development, Okazaki, Aichi, Japan, nishimura-yk@igakuken.or.jp