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Biomarkers as Surrogate Endpoints: Ongoing Opportunities for Validation

Published online by Cambridge University Press:  01 January 2021

Audrey D. Zhang  and
Joseph S. Ross
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Abstract

Surrogate endpoints are a common application of biomarkers to estimate clinical benefit in clinical trials, despite questions about reliability. This article discusses ongoing opportunities for their validation, in the context of a regulatory environment in which they are increasingly championed.

Type
Symposium Articles
Information
Journal of Law, Medicine & Ethics , Volume 47 , Issue 3: Biomarker Research and Validation: Current Challenges, Future Opportunities , Fall 2019 , pp. 393 - 395
Copyright
Copyright © American Society of Law, Medicine and Ethics 2019

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