Philosophers of science have variously tried to characterize how-possibly explanations (HPEs) and distinguish them from how-actually explanations (HAEs). I argue that existing contributions to this debate have failed to pay attention to the different, but complementary, functions possibilities play in scientific explanations. To bring these functions to the fore, I introduce a distinction between what I call elucidating and embedding HPEs. While elucidating HPEs specify and demonstrate possible processes for a given research target, embedding HPEs demonstrate how the research target (...) fits into a space of suitably constrained possibilities. I specify both functions of HPE with reference to two case studies from origins-of-life research. I contrast my distinction with an alternative proposal by Wirling and Grüne-Yanoff (2024) to highlight that focusing on the functions, rather than types, of possibilities in explanation is better suited to account for key scientific practices. (shrink)

The received view of scientific experimentation holds that science is characterized by experiment and experiment is characterized by active intervention on the system of interest. Although versions of this view are widely held, they have seldom been explicitly defended. The present essay reconstructs and defuses two arguments in defense of the received view: first, that intervention is necessary for uncovering causal structures, and second, that intervention conduces to better evidence. By examining a range of non-interventionist studies from across the sciences, (...) I conclude that interventionist experiments are not, ceteris paribus, epistemically superior to non-interventionist studies and that the latter may thus be classified as experiment proper. My analysis explains why intervention remains valuable while at the same time elevating the status of some non-interventionist studies to that of experiment proper. (shrink)

Popper’s (1983, 2002) philosophy of science has enjoyed something of a renaissance in the wake of the replication crisis, offering a philosophical basis for the ensuing science reform movement. However, adherence to Popper’s approach may also be at least partly responsible for the sense of “crisis” that has developed following multiple unexpected replication failures. In this article, I contrast Popper’s approach with that of Lakatos (1978) as well as with a related but problematic approach called naïve methodological falsificationism (NMF; Lakatos, (...) 1978). The Popperian approach is powerful because it is based on logical refutations, but its theories are noncausal and, therefore, potentially lacking in scientific value. In contrast, the Lakatosian approach considers causal theories, but it concedes that these theories are not logically refutable. Finally, NMF represents a hybrid approach that subjects Lakatosian causal theories to Popperian logical refutations. However, its tactic of temporarily accepting a ceteris paribus clause during theory testing may be viewed as scientifically inappropriate, epistemically inconsistent, and “completely redundant” (Lakatos, 1978, p. 40). I conclude that the replication “crisis” makes the most sense in the context of the Popperian and NMF approaches because it is only in these two approaches that the failure to replicate a previously corroborated theory represents a logical refutation of that theory. In contrast, such replication failures are less problematic in the Lakatosian approach because they do not logically refute theories. Indeed, in the Lakatosian approach, replication failures can be temporarily ignored or used to motivate theory development. (shrink)

Alan Hodgkin and Andrew Huxley used abductive reasoning to draw conclusions about the ionic basis of the action potential. Here we build on that initial proposal. First, we propose that Hodgkin and Huxley’s constitutive abductive reasoning has four features. Second, we argue that Hodgkin and Huxley are not alone in giving such arguments. Tolman, 1948, and Baumgartner, 1960, also gave such arguments. The implication is that such arguments are common enough in science that philosophers of science should pay more attention (...) to them. Third, we propose that constitutive abduction describes a method that scientists use to confirm constitutive hypotheses that is an alternative to the mutual manipulability approach that is familiar in the New Mechanist literature. (shrink)

In this paper, we will focus on a specific way in which non-epistemic values can influence scientific inquiry, i.e., how they affect the way in which members of a scientific community apply epistemic values. We will first introduce the concept of epistemic niche construction in science, that is, the idea that the epistemic commitments underlying the practice of a scientific community result from a feedback-loop process between the scientific practice itself and the related disciplinary matrix. We will then describe how (...) non-epistemic values can affect the different steps of this feedback-loop process. We will substantiate our argumentation through a historical case study: the rise and fall of nineteenth-century craniology. (shrink)

Stöltzner coined the expression ‘Vienna indeterminism’ to describe a philosophical tradition centered on the Viennese physicist Exner, serving as the ‘historical link’ between Mach and Boltzmann, on the one hand, and von Mises and Frank, on the other. During the early 1930s debate on quantum mechanics, there was a ‘rapprochement’ between Vienna indeterminism and Schlick’s work on causality. However, it was Cassirer’s 1936 monograph _Determinismus und Indeterminismus_ that showed a full ‘convergence’ with major tenets of Vienna indeterminism: the fundamentality of (...) statistical laws, the frequency interpretation of probability, and the statistical interpretation of the uncertainty relations. Yet, Cassirer used these conceptual tools to pursue ‘in parallel’ different philosophical goals. While for the Viennese quantum mechanics represented a fatal blow to the already discredited notion of ‘causality,’ for Cassirer it challenged the classical notion of ‘substantiality,’ the ideas of ‘particles’ as individual substances endowed with properties. The paper concludes that this ‘parallel convergence’ is the most striking and overlooked aspect of _Determinismus und Indeterminismus_, serving as the keystone of its argumentative structure. (shrink)

In operational quantum mechanics two measurements are called operationally equivalent if they yield the same distribution of outcomes in every quantum state and hence are represented by the same operator. In this paper, I will show that the ontological models for quantum mechanics and, more generally, for any operational theory sensitively depend on which measurement we choose from the class of operationally equivalent measurements, or more precisely, which of the chosen measurements can be performed simultaneously. To this goal, I will (...) take first three examples—a classical theory, the EPR-Bell scenario and the Popescu-Rochlich box; then realize each example by two operationally equivalent but different operational theories—one with a trivial and another with a non-trivial compatibility structure; and finally show that the ontological models for the different theories will be different with respect to their causal structure, contextuality, and fine-tuning. (shrink)

Performativity of science refers to the phenomenon that the dissemination of scientific conceptualisations can sometimes affect their target systems or referents. A widely held view in the literature is that scientists ought not to deliberately deploy performative models or theories with the aim of eliciting desirable changes in their target systems. This paper has three aims. First, I cast and defend this received view as a worry about autonomy-infringing paternalism and, to that end, develop a taxonomy of the harms it (...) can impose. Second, I consider various approaches to this worry within the extant literature and argue that these offer only unsatisfactory responses. Third, I propose two positive claims. Manipulation of target systems is (a) not inherently paternalist and can be unproblematic, and is (b) sometimes paternalist, but whenever such paternalism is inescapable, it has got to be justifiable. I generalise an example of modelling international climate change coordination to develop this point. (shrink)

Modal Empiricism in philosophy of science proposes to understand the possibility of modal knowledge from experience by replacing talk of possible worlds with talk of possible situations, which are coarse-grained, bounded and relative to background conditions. This allows for an induction towards objective necessity, assuming that actual situations are representative of possible ones. The main limitation of this epistemology is that it does not account for probabilistic knowledge. In this paper, we propose to extend Modal Empiricism to the probabilistic case, (...) thus providing an inductivist epistemology for probabilistic knowledge. The key idea is that extreme probabilities, close to 1 and 0, serve as proxies for testing mild probabilities, using a principle of model combination. (shrink)

This paper aims to evaluate the relevance of Kant’s much discussed essentialism and mechanism for present-day philosophy of psychiatry. Kendler et al (2011) have argued that essentialism is inadequate for conceptualizing psychiatric disorders. In this paper, I develop this argument in detail by highlighting a variety of essentialism that differs from the one rejected by Kendler et al. I show that Kant’s essentialism is not directly affected by the argument of Kendler et al (2011), and that Kendler et al’s (2011) (...) argument also does not affect other essentialist positions in psychiatry. Hence, the rejection of essentialism in psychiatry needs more arguments than the one supplied by Kendler et al. Nevertheless, the study of current psychiatry also provides reasons to reject Kant’s essentialism and his transcendental project. I argue that Kant’s theory of mechanical explanation is more relevant for analyzing present-day philosophy of psychiatry, insofar as (a) modern psychiatric research into the causes of psychiatric disorders fits the mechanist paradigm, (b) Kant’s theory of mechanical explanation is importantly similar to modern theories of mechanical explanation applicable to psychiatry, such as those of Bechtel and associates, and (c) Kant’s stance that mechanism constitutes a regulative ideal points to useful arguments for the pursuit of mechanical explanations in psychiatry. (shrink)

Empiricism has a long and venerable history. Aristotle, the Epicureans, Sextus Empiricus, Bacon, Locke, Hume, Mill, Mach and the Logical Empiricists, among others, represent a long line of historically influential empiricists who, one way or another, placed an emphasis on knowledge gained through the senses. In recent times the most highly articulated and influential edition of empiricism is undoubtedly Bas van Fraassen’s constructive empiricism. Science, according to this view, aims at empirically adequate theories, i.e. theories that save all and only (...) the observable phenomena. Roughly put, something is observable in van Fraassen’s view if members of the human epistemic community can detect it with their unaided senses. Critics have contested this notion, citing, among other reasons, that much of what counts as knowledge for scientists, especially in the natural sciences, concerns things that are detectable only with instruments, i.e. things that are unobservable and hence unknowable by van Fraassen’s lights. The current paper seeks to overcome this objection by putting forth and defending a liberalised conception of observability and an associated, and accordingly liberalised, conception of empiricism. ‘Grounded observability’ and ‘grounded empiricism’, as we call them, unchain themselves from the burdens of traditional conceptions of experience, while at the same time tethering themselves to the source of epistemic credibility in the senses, and, hence to the true spirit of empiricism. (shrink)

This paper investigates the status of inference to the best explanation (IBE), in contrast to inference to the only explanation (IOE) against the background of Woodward's what-if-things- had-been-different (w) account of explanation. It argues that IBE is not a defensible form of inference. By contrast IOE is defensible and objections to its use (e.g., on the basis of claims about underdetermination) are exaggerated. Although some accounts of explanation in conjunction support IBE, the w-account does not. It is also argued that (...) we should think of explanation as an independent goal of scientific investigation that is valuable in its own right and not because it is a means to discovering truths via IBE. The correct picture of the connection between explanation and truth is simply that successful explanation requires a true or effectively correct explanans. However, we cannot establish that an explanans has this feature by appealing to its potential explanatory power– that it would if true explain well. Instead, evidence that is independent of potential explanatory power is required. This is what IOE provides. (shrink)

Many philosophers have explored the extensive use of non-universal generalizations in different sciences for inductive and explanatory purposes, analyzing properties such as how widely a generalization holds in space and time. In the present paper, we concentrate on developmental biology to distinguish and characterize two common approaches to scientific generalization—mechanism generalization and principle generalization. The former approach seeks detailed descriptions of causal relationships among specific types of biological entities that produce a characteristic phenomenon across some range of different biological entities; (...) the latter approach abstractly describes relations or interactions that occur during ontogeny and are exemplified in a wide variety of different biological entities. These two approaches to generalization correspond to different investigative aims. Our analysis shows why each approach is sought in a research context, thereby accounting for how practices of inquiry are structured. It also diagnoses problematic assumptions in prior discussions, such as abstraction always being correlated positively with generalizations of wide scope. (shrink)

Critics frequently target Ernest Nagel’s model of reduction for its purported inadequacy in addressing the issue of approximation. In response, proponents of Nagel’s model have integrated approximations into the more comprehensive Generalized Nagel-Schaffner model, or the GNS model. However, this article contends that the pertinent criticisms and responses are both misplaced: There are no barriers to Nagel’s model incorporating approximations, and it assimilates them in a manner distinctly dissimilar to the approach of the GNS model. Indeed, Nagel’s model is fundamentally (...) _static_, providing invariant formal and informal conditions for reduction; and it is the _dynamic_ history of science that fulfills relevant conditions for reduction, thereby achieving different _degrees of reductive success_. Consequently, approximations are essentially extraneous to Nagel’s model, since they pertain chiefly to temporally based scientific knowledge and concern merely the _means_ (e.g., approximate or exact deductions) of fulfilling the conditions for reduction within specific problem contexts. This article also develops a Nagelian treatment of approximation, demonstrating how distinctive types of approximations aid in fulfilling various conditions for reduction and contribute to different degrees of reductive success. Two case studies are presented to illustrate the Nagelian treatment: The first examines the specific heat ratio anomaly within the traditional endeavor of reducing thermodynamics to statistical mechanics, and the second addresses the consumption puzzle in the context of reducing macroeconomics to microeconomics. (shrink)

A family of arguments for black hole evaporation relies on conservation laws, defined through symmetries represented by Killing vector fields which exist globally or asymptotically. However, these symmetries often rely on the idealizations of stationarity and asymptotic flatness, respectively. In non-stationary or non-asymptotically-flat spacetimes where realistic black holes evaporate, the requisite Killing fields typically do not exist. Can we ‘de-idealize’ these idealizations, and subsequently the associated arguments for black hole evaporation? Here, I critically examine the strategy of using ‘approximately Killing’ (...) fields to de-idealize black hole spacetimes and approximately extend conservation laws to non-idealized cases. I argue that this approach encounters significant challenges, undermining the use of these idealizations to justify the evaporation of realistic – rather than idealized – black holes, and raising questions about the justified use of such idealizations. (shrink)

Research about the evolution of morality suffers from the lack of a clear, agreed-upon concept of morality. In response to this, recent accounts have become increasingly pluralist and pragmatic. In this paper, I argue that 1) both the concept of morality and the broader understanding of what makes us moral include ethical and metaethical assumptions; 2) there is no uncontroversial descriptive notion available, and therefore settling on a particular concept inevitably entails such assumptions; and 3) what is lacking is a (...) reflection on the role that ethical and metaethical assumptions play, suggesting that the debate would benefit from making them explicit. Claims about “the true origin of morality” can fruitfully be analyzed as “mixed claims”: claims that combine a causal-historical hypothesis (e.g., about the evolution of a certain ability, such as empathy or joint intentionality) with ethical or metaethical assumptions about which abilities or norms make us moral. Making such assumptions explicit advances the epistemic aims of transparency and comparability, and thereby helps to avoid rash conclusions regarding, for instance, the nature of moral progress. Finally, it helps to unpack the normative knowledge shared by behavioral scientists and comparative psychologists and to give this knowledge its proper place in research. (shrink)

Famously, Adrian Moore has argued that an absolute representation of reality is possible: that it is possible to represent reality from no particular point of view. Moreover, Moore believes that such absolute representations are a desideratum of physics. Recently, however, debates in the philosophy of physics have arisen regarding the apparent impossibility of an absolute representation of certain aspects of nature in light of our current best theories of physics. Throughout this article, we take gravitational energy as a particular case (...) study of an aspect of nature that seemingly does not admit of an absolute representation. There is, therefore, a prima facie tension between Moore’s a priori case on the one hand, and the state-of-play in modern physics on the other. This article overcomes this tension by demonstrating how, when formulated in the correct way, modern physics admits of an absolute representation of gravitational energy after all. In so doing, the article offers a detailed case study of Moore’s argument for absolute representation, clarifying its structure and bringing it into contact with the distinction drawn by philosophers of physics between coordinate-freedom and coordinate-independence, as well as the philosophy of spacetime physics. (shrink)

Discussion of the extraterrestrial hypothesis (ETH), the hypothesis that an extraterrestrial civilization (ETC) is active on Earth today, is taboo in academia, but the assumptions behind this taboo are faulty. Advances in biology have rendered the notion that complex life is rare in our Galaxy improbable. The objection that no ETC would come to Earth to hide from us does not consider all possible alien motives or means. For an advanced ETC, the convergent instrumental goals of all rational agents – (...) self-preservation and the acquisition of resources – would support the objectives of removing existential threats and gathering strategic and non-strategic information. It could advance these objectives by proactively gathering information about and from inhabited planets, concealing itself while doing so, and terminating potential rivals before they become too dangerous. Other hypotheses of ETC behavior, including the zoo/interdict hypothesis and the dark forest hypothesis, also undercut the objection that the ETH is highly improbable. The ETH does not require support from extraordinary evidence because the presence of an ETC on Earth is not highly unlikely and would overturn none of our well-tested scientific knowledge. The fact that most reports of unidentified anomalous phenomena (UAP) have natural or human explanations does not count against it. Inference to the best explanation offers a way to find evidence for this hypothesis, and some evidence for it exists, some of it taking the form of reliable witness reports. The most plausible alternative explanation for some UAP reports declines in probability over time. A hypothesis that is not highly improbable, does not contradict any well-established facts or theories, and explains otherwise unexplained evidence is a rational hypothesis. Since the ETH is a rational hypothesis, investigation of it should not be taboo. (shrink)

Explanatory Essentialism (EE) is the view that a property is the essence of a kind because it causally explains the many properties that instances of the kind exhibit. This paper examines an application of EE to biological species, which I call Biological Explanatory Essentialism (BEE). BEE states that a particular biological origin is the essence of a species on the grounds that it causes certain organisms to display the group of properties the species is associated with. Evaluating BEE is important, (...) as it offers a novel argument for Biological Essentialism, the contentious claim that biological species have essences. The paper critically assesses the empirical foundations of BEE, focusing on the presupposition that a single biological origin causes the many properties associated with the species in question. By discussing a case of five-toed jerboas within the Scarturus elater species complex, I challenge that presupposition, thereby showing that cryptic species present a serious obstacle to BEE. I conclude that BEE fails to support Biological Essentialism, and suggest that essentialist philosophers reconsider the relevance of causal-explanatory factors in accounting for the purported essences of biological species. These philosophers may need to explore alternatives beyond such factors, one of which I briefly outline. (shrink)

We showed in a recent article (Lawrence et al. 2023. Quantum, 7, 1015), that relative facts (outcomes), a central concept in Relational Quantum Mechanics, are inconsistent with Quantum Mechanics. We proved this by constructing a Wigner-Friend type sequential measurement scenario on a Greenberger-Horne-Zeilinger (GHZ) state of three qubits, and making the following assumption: “if an interpretation of quantum theory introduces some conceptualization of outcomes of a measurement, then probabilities of these outcomes must follow the quantum predictions as given by the (...) Born rule.” Our work has been criticized by Cavalcanti et al. (2023. European Journal for Philosophy of Science, 13(4),55). In this note we show that their critique, based on their own reformulation of our argument, does not apply to our paper. It also raises questions of principle which are not answered within the framework of Relational Quantum Mechanics. (shrink)

This article mainly investigates whether common Bayesian confirmation measures are affected by stopping rules. The results indicate that difference measure d, log-ratio measure r, and log-likelihood measure l are not affected by non-informative stopping rules, but affected by informative stopping rules. In contrast, Carnap measure $$\tau $$, normalized difference measure n, and Mortimer measure m are affected by (non-)informative stopping rules sometimes but sometimes aren’t. Besides, we use two examples to further illustrate that confirmation measures d, r, and l are (...) better than $$\tau,n$$, and m. (shrink)

The degreed view is an influential account in the debate on quantum value indefiniteness, linking the gradedness of quantum properties to quantum indeterminacy. This paper challenges the connection between degrees and indeterminacy by presenting an example of a graded quantum property that does not entail metaphysical indeterminacy. Through an investigation of two graded approaches to location in quantum mechanics, the paper argues that while the first account, degreed instantiation of exact location, is indeterminate, the second account, degreed quantum location, is (...) not. This indicates that indeterminacy and degrees are not inherently linked, offering a novel perspective on quantum ontology. The paper advocates adopting a graded view of quantum properties without indeterminacy, potentially leading to a paradigm shift in understanding quantum phenomena. (shrink)

Performativity refers to the phenomenon that scientific conceptualisations can sometimes change their target systems or referents. A widely held view in the literature is that scientists ought not to deliberately deploy performative models or theories with the aim of eliciting desirable changes in their target systems. This paper has three aims. First, I cast and defend this received view as a worry about autonomy-infringing paternalism and, to that end, develop a taxonomy of the harms it can impose. Second, I consider (...) various approaches to this worry within the extant literature and argue that these offer only unsatisfactory responses. Third, I propose two positive claims. Manipulation of target systems is (a) not inherently paternalist and can be unproblematic, and is (b) sometimes paternalist, but whenever such paternalism is inescapable, it has got to be justifiable. I generalise an example of modelling international climate change coordination to develop this point. (shrink)

Popper’s (1983, 2002) philosophy of science has enjoyed something of a renaissance in the wake of the replication crisis, offering a philosophical basis for the ensuing science reform movement. However, adherence to Popper’s approach may also be at least partly responsible for the sense of “crisis” that has developed following multiple unexpected replication failures. In this article, I contrast Popper’s approach with that of Lakatos (1978) as well as with a related but problematic approach called naïve methodological falsificationism (NMF; Lakatos, (...) 1978). The Popperian approach is powerful because it is based on logical refutations, but its theories are noncausal and, therefore, potentially lacking in scientific value. In contrast, the Lakatosian approach considers causal theories, but it concedes that these theories are not logically refutable. Finally, NMF represents a hybrid approach that subjects Lakatosian causal theories to Popperian logical refutations. However, its tactic of temporarily accepting a ceteris paribus clause during theory testing may be viewed as scientifically inappropriate, epistemically inconsistent, and “completely redundant” (Lakatos, 1978, p. 40). I conclude that the replication “crisis” makes the most sense in the context of the Popperian and NMF approaches because it is only in these two approaches that the failure to replicate a previously corroborated theory represents a logical refutation of that theory. In contrast, such replication failures are less problematic in the Lakatosian approach because they do not logically refute theories. Indeed, in the Lakatosian approach, replication failures can be temporarily ignored or used to motivate theory development. (shrink)

Several philosophers of science have taken inspiration from biological research on niches to conceptualise scientific practice. We systematise and extend three niche-based theories of scientific practice: conceptual ecology, cognitive niche construction, and scientific niche construction. We argue that research niches are a promising conceptual tool for understanding complex and dynamic research environments, which helps to investigate relevant forms of agency and material and social interdependencies, while also highlighting their historical and dynamic nature. To illustrate this, we develop a six-point framework (...) for conceptualising research niches. Within this framework, research niches incorporate multiple and heterogenous material, social and conceptual factors (multi-dimensionality); research outputs arise, persist and differentiate through interactions between researchers and research niches (processes); researchers actively respond to and construct research niches (agency); research niches enable certain interactions and processes and not others (capability); and research niches are defined in relation to particular entities, such as individual researchers, disciplines, or concepts (relationality), and in relation to goals, such as understanding, solving problems, intervention, or the persistence of concepts or instruments (normativity). (shrink)

We rigorously describe the relation in which a credence function should stand to a set of chance functions in order for these to be compatible in the way mandated by the Principal Principle. This resolves an apparent contradiction in the literature, by means of providing a formal way of combining credences with modest chance functions so that the latter indeed serve as guides for the former. Along the way we note some problematic consequences of taking admissibility to imply requirements involving (...) probabilistic independence. We also argue, contra (Hawthorne et al., The British Journal for the Philosophy of Science, 68(1), 123–131 2017), that the Principal Principle does not imply the Principle of Indifference. (shrink)

For some post-structuralist complexity theorists, there are no epistemic meta-perspectives from where to judge between different epistemic perspectives toward complex systems. In this paper, I argue that these theorists face a dilemma because they argue against meta-perspectives from just such a meta-perspective. In fact, when we understand two or more different perspectives, we seem to unavoidably adopt a meta-perspective to analyse, compare, and judge between those perspectives. I further argue that meta-perspectives can be evaluated and judged from meta-meta-perspectives, and so (...) on. This suggests an epistemic hierarchy. Perspectives, meta-perspectives, meta-meta-perspectives, etc. can be ranked according to the degree to which they confer understanding. I also explore what scope my thesis might have outside the philosophy of complexity by applying it to the sociology of science. (shrink)