Developing World Bioethics 15 (2):107-112 (2015)

During the past two decades, Iran has experienced a noteworthy growth in its biomedical research sector. At the same time, ethical concerns and debates resulting from this burgeoning enterprise has led to increasing attention paid to biomedical ethics. In Iran, Biomedical research ethics and research oversight passed through major periods during the past decades, separated by a paradigm shift. Period 1, starting from the early 1970s, is characterized by research paternalism and complete reliance on researchers as virtuous and caring physicians. This approach was in concordance with the paternalistic clinical practice of physicians outside of research settings during the same period. Period 2, starting from the late 1990s, was partly due to revealing of ethical flaws that occurred in biomedical research in Iran. The regulatory and funding bodies concluded that it was not sufficient to rely solely on the personal and professional virtues of researchers to safeguard human subjects' rights and welfare. The necessity for independent oversight, emphasized by international declarations, became obvious and undeniable. This paradigm shift led to the establishment of research ethics committees throughout the country, the establishment of academic research centers focusing on medical ethics and the compilation of the first set of national ethical guidelines on biomedical research–one of the first and most important projects conducted by and in the MEHR. Although not yet arrived, ‘period 3’ is on its way. It is predictable from the obvious trends toward performance of high-quality clinical research and the appearance of a highly educated new generation, especially among women
Keywords biomedical research ethics  paradigm shift  Iran  research oversight  history
Categories (categorize this paper)
DOI 10.1111/dewb.12053
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 56,988
Through your library

References found in this work BETA

Four Paradigms of Clinical Research and Research Oversight.Ezekiel J. Emanuel & Christine Grady - 2007 - Cambridge Quarterly of Healthcare Ethics 16 (1):82-96.
Contemporary Medical Ethics: An Overview From Iran.Bagher Larijani & Farzaneh Zahedi - 2008 - Developing World Bioethics 8 (3):192-196.

View all 6 references / Add more references

Citations of this work BETA

No citations found.

Add more citations

Similar books and articles

The Ethics of Research on Enhancement Interventions.Lev Ori, G. Miller Franklin & J. Emanuel Ezekiel - 2010 - Kennedy Institute of Ethics Journal 20 (2):101-113.
The Responsible Conduct of Basic and Clinical Research.Andrzej Górski - 2006 - Science and Engineering Ethics 12 (1):3-4.
Non-Human Primates: The Appropriate Subjects of Biomedical Research?M. Quigley - 2007 - Journal of Medical Ethics 33 (11):655-658.
Catholic Social Teaching as a Framework for Research Ethics.Alan J. Kearns - 2014 - Journal of Academic Ethics 12 (2):145-159.
The Concept of Risk and Responsible Conduct of Research.Eugenijus Gefenas - 2006 - Science and Engineering Ethics 12 (1):75-83.


Added to PP index

Total views
50 ( #199,981 of 2,410,262 )

Recent downloads (6 months)
1 ( #540,207 of 2,410,262 )

How can I increase my downloads?


My notes