Neuroscience and Biobehavioral Reviews 37 (10):2721-2736 (2013)

Andrew And Alexander Fingelkurts
BM-Science - Brain and Mind Technologies Research Centre
Unresponsive wakefulness syndrome (UWS, previously known as vegetative state) occurs after patients survive a severe brain injury. Patients suffering from UWS have lost awareness of themselves and of the external environment and do not retain any trace of their subjective experience. Current data demonstrate that neuronal functions subtending consciousness are not completely reset in UWS; however, they are reduced below the threshold required to experience consciousness. The critical factor that determines whether patients will recover consciousness is the distance of their neuronal functions from this threshold level. Recovery of consciousness occurs through functional and/or structural changes in the brain, i.e., through neuronal plasticity. Although some of these changes may occur spontaneously, a growing body of evidence indicates that rehabilitative interventions can improve functional outcome by promoting adaptive functional and structural plasticity in the brain, especially if a comprehensive neurophysiological theory of consciousness is followed. In this review we will focus on the pathophysiological mechanisms involved in UWS and on the plastic changes operating on the recovery of consciousness.
Keywords Vegetative state  Minimally conscious state  Consciousness  Awareness  EEG  Rehabilitation  Traumatic brain injuries (TBI)  Operational Architectonics  Neuronal assemblies synchrony
Categories (categorize this paper)
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 60,795
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

No references found.

Add more references

Citations of this work BETA

Actual Physical Potentiality for Consciousness.Andrew And Alexander Fingelkurts - 2018 - American Journal of Bioethics Neuroscience 9 (1):24-25.

View all 6 citations / Add more citations

Similar books and articles

Thought Translation, Tennis and Turing Tests in the Vegetative State.John F. Stins & Steven Laureys - 2009 - Phenomenology and the Cognitive Sciences 8 (3):361-370.
Brain Damage and the Moral Significance of Consciousness.Guy Kahane & Julian Savulescu - 2009 - Journal of Medicine and Philosophy 34 (1):6-26.


Added to PP index

Total views
65 ( #160,016 of 2,438,793 )

Recent downloads (6 months)
1 ( #436,491 of 2,438,793 )

How can I increase my downloads?


My notes