Benefits to research subjects in international trials: Do they reduce exploitation or increase undue inducement?

Developing World Bioethics 8 (3):178-191 (2008)

Abstract
There is an alleged tension between undue inducement and exploitation in research trials. This paper considers claims that increasing the benefits to research subjects enrolled in international, externally-sponsored clinical trials should be avoided on the grounds that it may result in the undue inducement of research subjects. This article contributes to the debate about exploitation versus undue inducement by introducing an analysis of the available empirical research into research participants' motivations and the influence of payments on research subjects' behaviour and risk assessment. Admittedly, the available research in this field is limited, but the research that has been conducted suggests that financial rewards do not distort research subjects' behaviour or blind them to the risks involved with research. Therefore, I conclude that research sponsors should prioritise the prevention of exploitation in international research by providing greater benefits to research participants. (edited)
Keywords research ethics  clinical trials  developing world  benefit sharing  justice  consent
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DOI 10.1111/j.1471-8847.2006.00175.x
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References found in this work BETA

Defining and Describing Benefit Appropriately in Clinical Trials.Nancy M. P. King - 2000 - Journal of Law, Medicine and Ethics 28 (4):332-343.

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Citations of this work BETA

How Payment For Research Participation Can Be Coercive.Joseph Millum & Michael Garnett - 2019 - American Journal of Bioethics 19 (9):21-31.
How to Do Research Fairly in an Unjust World.Angela J. Ballantyne - 2010 - American Journal of Bioethics 10 (6):26-35.

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