Theoretical sequelae of a chronic neglect and unawareness of prefrontotectal pathways in the human brain

Behavioral and Brain Sciences 30 (1):83-85 (2007)
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Attention research with prefrontal patients supports Merker's argument regarding the crucial role for the midbrain in higher cognition, through largely overlooked and misunderstood prefrontotectal connectivity. However, information theoretic analyses reveal that both exogenous (i.e., collicular) and endogenous (prefrontal) sources of information are responsible for large-scale context-sensitive brain dynamics, with prefrontal cortex being at the top of the hierarchy for cognitive control. (Published Online May 1 2007).



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