Reconceptualizations and interfield connections: The discovery of the link between vitamins and coenzymes

Philosophy of Science 51 (2):265-292 (1984)
The discovery that some B vitamins are constituents of respiratory coenzymes led to the development of an interfield theory of the kind discussed by Darden and Maull. In this paper it is shown that the development of a useful interfield connection was made possible by two reconceptualizations: a reconceptualization that united two then-distinct fields giving rise to the concept of vitamins as dietary substances; and another reconceptualization that united two approaches to respiratory metabolism producing the idea that coenzymes are transport vehicles.
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DOI 10.1086/289180
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