Xenotransplantation Clinical Trials and Equitable Patient Selection

Cambridge Quarterly of Healthcare Ethics 33 (3):425-434 (2024)
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Abstract

Xenotransplant patient selection recommendations restrict clinical trial participation to seriously ill patients for whom alternative therapies are unavailable or who will likely die while waiting for an allotransplant. Despite a scholarly consensus that this is advisable, we propose to examine this restriction. We offer three lines of criticism: (1) The risk–benefit calculation may well be unfavorable for seriously ill patients and society; (2) the guidelines conflict with criteria for equitable patient selection; and (3) the selection of seriously ill patients may compromise informed consent. We conclude by highlighting how the current guidance reveals a tension between the societal values of justice and beneficence.

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Author Profiles

Christopher A. Bobier
Central Michigan University
Daniel Rodger
London South Bank University