In Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.), Systems Biology: Philosophical Foundations. Elsevier (2007)

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Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation.Ingo Brigandt - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
Mechanistic Explanation in Systems Biology: Cellular Networks.Dana Matthiessen - 2017 - British Journal for the Philosophy of Science 68 (1):1-25.

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