State-dependent suppression of LTP induction after learning: Relation to phasic hippocampal network events

Behavioral and Brain Sciences 20 (4):614-615 (1997)
This commentary argues that (1) arousal is not sufficient to induce LTP in the hippocampus, (2) learning can profoundly modulate synaptic plasticity in a state-dependent manner without affecting baseline synaptic efficacy, and (3) unilateral, synapse-specific LTP induction triggers an interhippocampal communication manifested as bilateral increases in gene expression at multiple sites in the hippocampal network.
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DOI 10.1017/S0140525X97231596
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