Journal of Medical Ethics (2):1-6 (2016)

Authors
Lara Buchak
Princeton University
Abstract
Some early phase clinical studies of candidate HIV cure and remission interventions appear to have adverse medical risk–benefit ratios for participants. Why, then, do people participate? And is it ethically permissible to allow them to participate? Recent work in decision theory sheds light on both of these questions, by casting doubt on the idea that rational individuals prefer choices that maximise expected utility, and therefore by casting doubt on the idea that researchers have an ethical obligation not to enrol participants in studies with high risk–benefit ratios. This work supports the view that researchers should instead defer to the considered preferences of the participants themselves. This essay briefly explains this recent work, and then explores its application to these two questions in more detail.
Keywords Decision-making  Research Ethics  HIV Infection and AIDS  Risk-weighted Expected Utility  Expected Utility
Categories (categorize this paper)
Reprint years 2017
DOI 10.1136/medethics-2015-103118
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

 PhilArchive page | Other versions
Through your library

References found in this work BETA

The Foundations of Statistics.Leonard J. Savage - 1956 - Philosophy of Science 23 (2):166-166.

Add more references

Citations of this work BETA

View all 6 citations / Add more citations

Similar books and articles

Risk and Rationality.Lara Buchak - 2013 - Oxford University Press.
Risk and Tradeoffs.Lara Buchak - 2014 - Erkenntnis 79 (S6):1091-1117.
Revisiting Risk and Rationality: A Reply to Pettigrew and Briggs.Lara Buchak - 2015 - Canadian Journal of Philosophy 45 (5):841-862.
Expected Utility Without Utility.E. Castagnoli & M. Li Calzi - 1996 - Theory and Decision 41 (3):281-301.
Decision-Value Utilitarianism.Wesley Cooper - 2008 - Polish Journal of Philosophy 2 (2):39-50.
On Risk and Rationality.Brad Armendt - 2014 - Erkenntnis 79 (S6):1-9.
Expected Utility and Risk.Paul Weirich - 1986 - British Journal for the Philosophy of Science 37 (4):419-442.
Nozick, Ramsey, and Symbolic Utility.Wesley Cooper - 2008 - Utilitas 20 (3):301-322.
Conditional Utility and its Place in Decision Theory.Paul Weirich - 1980 - Journal of Philosophy 77 (11):702-715.
On the Application of J.M. Keynes's Approach to Decision Making.Michael E. Brady - 1994 - International Studies in the Philosophy of Science 8 (2):99 – 112.

Analytics

Added to PP index
2016-07-05

Total views
398 ( #20,055 of 2,432,823 )

Recent downloads (6 months)
84 ( #8,067 of 2,432,823 )

How can I increase my downloads?

Downloads

My notes