Hastings Center Report 47 (5):7-9 (2017)
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Abstract |
The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom as the most likely location for the first MRT birth, so it was a shock when, on September 27, 2016, an announcement went out that the first baby to result from use of the intervention had already been born. In New York City, United States-based scientist John Zhang used maternal spindle transfer to generate five embryos for a woman carrying oocytes with deleterious mutations of the mitochondrial DNA. Zhang then shipped the only euploid embryo to Mexico, where it was transferred to the mother's uterus. Zhang's team's travel across international borders to carry out experimental procedures represents a form of scientific tourism that has not been properly ethically explored; it can, however, have seriously detrimental effects for developing countries.
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DOI | 10.1002/hast.763 |
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References found in this work BETA
Mitochondrial Replacement Techniques and Mexico’s Rule of Law: On the Legality of the First Maternal Spindle Transfer Case.César Palacios-González - 2017 - Journal of Law and the Biosciences 4 (1):50–69.
On Moral Incoherence and Hidden Battles: Stem Cell Research in Argentina.Florencia Luna & Arleen Salles - 2010 - Developing World Bioethics 10 (3):120-128.
Citations of this work BETA
The Need for Donor Consent in Mitochondrial Replacement.G. Owen Schaefer - 2018 - Journal of Medical Ethics 44 (12):825-829.
Germline Modification and Policymaking: The Relationship Between Mitochondrial Replacement and Gene Editing.Jessica Cussins & Leah Lowthorp - 2018 - The New Bioethics 24 (1):74-94.
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