A Framework for Unrestricted Prenatal Whole-Genome Sequencing: Respecting and Enhancing the Autonomy of Prospective Parents

American Journal of Bioethics 17 (1):3-18 (2017)

Abstract

Noninvasive, prenatal whole genome sequencing may be a technological reality in the near future, making available a vast array of genetic information early in pregnancy at no risk to the fetus or mother. Many worry that the timing, safety, and ease of the test will lead to informational overload and reproductive consumerism. The prevailing response among commentators has been to restrict conditions eligible for testing based on medical severity, which imposes disputed value judgments and devalues those living with eligible conditions. To avoid these difficulties, we propose an unrestricted testing policy, under which prospective parents could obtain information on any variant of known significance after a careful informed consent process that uses an interactive decision aid to deliver a mandatory presentation on the purposes, techniques, and limitations of genomic testing, as well as optional resources for reflection and consultation. This process would encourage thoughtful, informed deliberation...

Download options

PhilArchive



    Upload a copy of this work     Papers currently archived: 72,805

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Analytics

Added to PP
2016-12-21

Downloads
18 (#614,253)

6 months
1 (#386,031)

Historical graph of downloads
How can I increase my downloads?

Author's Profile

Similar books and articles

Wisdom, Casuistry, and the Goal of Reproductive Counseling.Anders Nordgren - 2002 - Medicine, Health Care and Philosophy 5 (3):281-289.
Antenatal Genetic Testing and the Right to Remain in Ignorance.Bennett Rebecca - 2001 - Theoretical Medicine and Bioethics 22 (5):461-471.
A Response to Nelson and Mahowald.Adrienne Asch & David Wasserman - 2007 - Cambridge Quarterly of Healthcare Ethics 16 (4):468.
A New Era in Prenatal Testing: Are We Prepared? [REVIEW]Dagmar Schmitz - 2013 - Medicine, Health Care and Philosophy 16 (3):357-364.
Parental Duties and Untreatable Genetic Conditions.H. Clarkeburn - 2000 - Journal of Medical Ethics 26 (5):400-403.