Authors
Lindley Darden
University of Maryland, College Park
Abstract
Philosophers have proposed various kinds of relations between Mendelian genetics and molecular biology: reduction, replacement, explanatory extension. This paper argues that the two fields are best characterized as investigating different, serially integrated, hereditary mechanisms. The mechanisms operate at different times and contain different working entities. The working entities of the mechanisms of Mendelian heredity are chromosomes, whose movements serve to segregate alleles and independently assort genes in different linkage groups. The working entities of numerous mechanisms of molecular biology are larger and smaller segments of DNA plus related molecules. Discovery of molecular DNA mechanisms filled black boxes that were noted, but unilluminated, by Mendelian genetics
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DOI 10.1016/j.shpsc.2005.03.007
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References found in this work BETA

Thinking About Mechanisms.Peter Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
Unity of Science as a Working Hypothesis.Paul Oppenheim & Hilary Putnam - 1958 - Minnesota Studies in the Philosophy of Science 2:3-36.
Explanatory Unification and the Causal Structure of the World.Philip Kitcher - 1989 - In Philip Kitcher & Wesley Salmon (eds.), Scientific Explanation. Minneapolis: University of Minnesota Press. pp. 410-505.

View all 25 references / Add more references

Citations of this work BETA

The Concept of Mechanism in Biology.Daniel J. Nicholson - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):152-163.
Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation.Ingo Brigandt - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
Lineage Explanations: Explaining How Biological Mechanisms Change: Articles.Brett Calcott - 2009 - British Journal for the Philosophy of Science 60 (1):51-78.

View all 34 citations / Add more citations

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