Editing the Genome of Human Beings: CRISPR-Cas9 and the Ethics of Genetic Enhancement

Journal of Evolution and Technology 27 (1):24-42 (2017)
  Copy   BIBTEX


In 2015 a team of scientists used a new gene-editing technique called CRISPR-Cas9 to edit the genome of 86 non-viable human embryos. The experiment sparked a global debate on the ethics of gene editing. In this paper; I first review the key ethical issues that have been addressed in this debate. Although there is an emerging consensus now that research on the editing of human somatic cells for therapeutic purpose should be pursued further; the prospect of using gene-editing techniques for the purpose of human enhancement has been met with strong criticism. The main thesis that I defend in this paper is that some of the most vocal objections recently raised against the prospect of genetic human enhancement are not justified. I put forward two arguments for the morality of genetic human enhancement. The first argument shows how the moral and legal framework within which we currently claim our procreative rights; especially in the context of IVF procedures; could be deployed in the assessment of the morality and legality of genetic human enhancement. The second argument calls into question the assumption that the average level of human cognitive performance should have a normative character.



    Upload a copy of this work     Papers currently archived: 92,075

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Human Genome Editing and Ethical Considerations.Kewal Krishan, Tanuj Kanchan & Bahadur Singh - 2016 - Science and Engineering Ethics 22 (2):597-599.
Debating Ethical Issues in Genome Editing Technology.Renzong Qiu - 2016 - Asian Bioethics Review 8 (4):307-326.
Crowdsourcing the Moral Limits of Human Gene Editing?Eric T. Juengst - 2017 - Hastings Center Report 47 (3):15-23.
Human germline editing: a historical perspective.Michel Morange - 2017 - History and Philosophy of the Life Sciences 39 (4):34.
Trust in Science: CRISPR–Cas9 and the Ban on Human Germline Editing.Stephan Guttinger - 2018 - Science and Engineering Ethics 24 (4):1077-1096.
CRISPR Becomes Clearer.Andrew W. Torrance - 2017 - Hastings Center Report 47 (5):5-6.
The Moral Significance of the Therapy-Enhancement Distinction in Human Genetics.David B. Resnik - 2000 - Cambridge Quarterly of Healthcare Ethics 9 (3):365-377.
“Editing”: A Productive Metaphor for Regulating CRISPR.Ben Merriman - 2015 - American Journal of Bioethics 15 (12):62-64.


Added to PP

111 (#159,776)

6 months
12 (#214,382)

Historical graph of downloads
How can I increase my downloads?

Author's Profile

Marcelo De Araujo
Universidade do Estado do Rio de Janeiro

Citations of this work

The gene-editing of super-ego.Bjørn Hofmann - 2018 - Medicine, Health Care and Philosophy 21 (3):295-302.

Add more citations