Mens Sana Monographs 10 (1):45 (2012)

Abstract
Attention deficit hyperactivity disorder is a developmental disorder with an age onset prior to 7 years. Children with ADHD have significantly lower ability to focus and sustain attention and also score higher on impulsivity and hyperactivity. Stimulants, such as methylphenidate, have remained the mainstay of ADHD treatment for decades with evidence supporting their use. However, recent years have seen emergence of newer drugs and drug delivery systems, like osmotic release oral systems and transdermal patches, to mention a few. The use of nonstimulant drugs like atomoxetine and various other drugs, such as a-agonists, and a few antidepressants, being used in an off-label manner, have added to the pharmacotherapy of ADHD. This review discusses current trends in drug therapy of ADHD and highlights the promise pharmacogenomics may hold in the future
Keywords ADHD   _α_-agonists   Antidepressants   Atomoxetine   Attention deficit hyperactivity disorder   Bupropion   Children   Clonidine   Dopamine   Drug delivery systems   Guanfacine   Lisdexamphetamine (LDX)   Methylphenidate   Mixed Amphetamine Salts   Modafini
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DOI 10.4103/0973-1229.87261
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