Perspectives on Science 19 (3):235-262 (2011)

Melinda Bonnie Fagan
University of Utah
Stem cell biology is driven by experiment. Its major achievements are striking experimental productions: "immortal" human cell lines from spare embryos (Thomson et al. 1998); embryo-like cells from "reprogrammed" adult skin cells (Takahashi and Yamanaka 2006); muscle, blood and nerve tissue generated from stem cells in culture (Lanza et al. 2009, and references therein). Well-confirmed theories are not so prominent, though stem cell biologists do propose and test hypotheses at a profligate rate. 1 This paper aims to characterize the role of experiment in stem cell biology, so as to answer the following question: how do experiments contribute to our knowledge of stem cells and related phenomena? The ..
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DOI 10.1162/POSC_a_00045
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Laws and Symmetry.Bas C. van Fraassen - 1989 - Oxford University Press.
How Models Are Used to Represent Reality.Ronald N. Giere - 2004 - Philosophy of Science 71 (5):742-752.
Discovering Cell Mechanisms: The Creation of Modern Cell Biology.William Bechtel - 2007 - Journal of the History of Biology 40 (1):185-187.

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