Human and animal research guidelines: Aligning ethical constructs with new scientific developments

Bioethics 25 (8):472-478 (2011)
Both human research and animal research operate within established standards and procedures. Although the human research environment has been criticized for its sometimes inefficient and imperfect process, reported abuses of human subjects in research served as the impetus for the establishment of the Nuremberg Code, Declaration of Helsinki, and the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and the resulting Belmont Report. No similar, comprehensive and principled effort has addressed the use of animals in research. Although published policies regarding animal research provide relevant regulatory guidance, these policies have not emerged from the process of specifying consistent and reasoned ethical principles. The lack of a fundamental effort to explore the ethical issues and principles regarding the use of animals in research has led to unclear and disparate policies. Recent studies have increased our understanding of animal cognition and emotion, suggesting that animals' potential for experiencing a wide variety of harms, such as pain and fear, is greater than has been previously appreciated. Furthermore, relationships between methods of captivity and certain laboratory procedures and the resulting adverse physical, social and psychological effects have been established. In light of this information, current protections may need to be reconsidered and modified. This paper explores the historical convergence and divergence in the creation of human and animal research guidelines, as well as opportunities to align ethical frameworks with new scientific discoveries
Keywords animal experiments  human research  animal research  research guidelines
Categories (categorize this paper)
DOI 10.1111/j.1467-8519.2011.01923.x
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history
Request removal from index
Download options
Our Archive

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 28,165
Through your library
References found in this work BETA

No references found.

Add more references

Citations of this work BETA

Add more citations

Similar books and articles
Protection of Animal Research Subjects.Czesław Radzikowski - 2006 - Science and Engineering Ethics 12 (1):103-110.
Attitudes to Animals: Views in Animal Welfare.Francine L. Dolins (ed.) - 1999 - Cambridge University Press.
Responsible Conduct of Research.Adil E. Shamoo - 2009 - Oxford University Press.
Animal Ethics: Toward an Ethics of Responsiveness.Kelly Oliver - 2010 - Research in Phenomenology 40 (2):267-280.
Standards for Animal Research: Looking at the Middle.Rebecca Dresser - 1988 - Journal of Medicine and Philosophy 13 (2):123-143.
On Justifying the Exploitation of Animals in Research.S. F. Sapontzis - 1988 - Journal of Medicine and Philosophy 13 (2):177-196.

Monthly downloads

Added to index


Total downloads

42 ( #124,053 of 2,172,021 )

Recent downloads (6 months)

1 ( #325,967 of 2,172,021 )

How can I increase my downloads?

My notes
Sign in to use this feature

There  are no threads in this forum
Nothing in this forum yet.

Other forums