Altered Structure of Dynamic Electroencephalogram Oscillatory Pattern in Major Depression.

Biological Psychiatry:in press (2014)

Authors
Andrew And Alexander Fingelkurts
BM-Science - Brain and Mind Technologies Research Centre
Abstract
Research on electroencephalogram (EEG) characteristics associated with major depressive disorder (MDD) has accumulated diverse neurophysiologic findings related to the content, topography, neurochemistry, and functions of EEG oscillations. Significant progress has been made since the first landmark EEG study on affective disorders by Davidson 35 years ago. A systematic account of these data is important and necessary for building a consistent neuropsychophysiologic model of MDD and other affective disorders. Given the extensive data on frequency-dependent functional significance of EEG oscillations, a frequency domain approach may reveal the types of brain functions involved and disturbed in MDD. In this review, we systematize and integrate diverse and often unconnected observations on the content, topography, neurochemistry, and functions of EEG oscillations involved in MDD within the general concept of an EEG oscillatory pattern.
Keywords Anxiety  Brain connectivity  Electroencephalogram  Interhemisphere asymmetry  Major depression  Oscillatory patterns  Spectral power  Transcranial magnetic stimulation  TMS
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