Authors | |
Abstract |
From the beginnings of the biochemistry as discipline, the dichotomy between in vivo- in vitro conditions has been in the center of their methodological discussions. With the growing influence of computer simulations - sometimes called "in silico" conditions-, a new methodological problem is added to biochemistry. However, "simulation" could be seen as a core concept that is in fact used in the in vivo - in vitro dichotomy. In this sense, in silico dimension could be considered as a natural extension of the classical dichotomy. From the way in which simulation is used on in vivo-in vitro dichotomy, we also suggest that the general idea of simulation proposed by Hartmann have to be redefined. The intuitive idea of simulation resting on “imitation” relationship, as a “process that imitates another process” (Hartmann 1996), has to be complemented by others methodological concepts like “isolation” or “disruption”.
|
Keywords | No keywords specified (fix it) |
Categories | (categorize this paper) |
Options |
![]() ![]() ![]() ![]() |
Download options
References found in this work BETA
The World as a Process: Simulations in the Natural and Social Sciences.Stephan Hartmann - 1996 - In Rainer Hegselmann (ed.), Modelling and Simulation in the Social Sciences from the Philosophy of Science Point of View.
Citations of this work BETA
No citations found.
Similar books and articles
The Legal Status of the Embryo in Vivo and in Vitro: Research on and the Medical Treatment of Embryos.H. J. J. Leenen - 1986 - Journal of Law, Medicine and Ethics 14 (3-4):129-132.
In Vivo Interpretation of in Vitro Effect Studies with a Detailed Analysis of the Method of in Vitro Transcription in Isolated Cell Nuclei.Roger Strand, Ragnar Fjelland & Torgeir Flatmark - 1996 - Acta Biotheoretica 44 (1):1-21.
Philosophy and Biochemistry: Research at the Interface Between Chemistry and Biology. [REVIEW]Claus Jacob - 2002 - Foundations of Chemistry 4 (2):97-125.
Scientific Theories as Intervening Representations.Thomas Mormann & Andoni Ibarra - 2006 - Theoria 21 (1):21-38.
“More on Respect for Embryos and Potentiality: Does Respect for Embryos Entail Respect for in Vitro Embryos?”.Stephen S. Hanson - 2006 - Theoretical Medicine and Bioethics 27 (3):215-226.
Segmentation and a Oral Status in Vivo and in Vitro: A Scientific Perspective.Karen Dawson - 1988 - Bioethics 2 (1):1–14.
A Proliferation Control Network Model: The Simulation of Two-Dimensional Epithelial Homeostasis.Didier Morel, Raphaël Marcelpoil & Gérard Brugal - 2001 - Acta Biotheoretica 49 (4):219-234.
Towards a Useful Philosophy of Biochemistry: Sketches and Examples. [REVIEW]Roger Strand - 1999 - Foundations of Chemistry 1 (3):269-292.
New Times for Biology: Nerve Cultures and the Advent of Cellular Life in Vitro.H. Landecker - 2002 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (4):667-694.
Analytics
Added to PP index
2009-01-28
Total views
43 ( #261,271 of 2,499,260 )
Recent downloads (6 months)
1 ( #418,195 of 2,499,260 )
2009-01-28
Total views
43 ( #261,271 of 2,499,260 )
Recent downloads (6 months)
1 ( #418,195 of 2,499,260 )
How can I increase my downloads?
Downloads