Beyond attention: The role of amygdala NMDA receptors in fear conditioning

Behavioral and Brain Sciences 20 (4):618-619 (1997)

Abstract

Several types of amygdala-dependent learning can be blocked by local infusion of NMDA antagonists into the amygdala. This blockade shows anatomical, pharmacological, temporal, and behavioral specificity, providing a pattern of data more consistent with a role for NMDA receptors in learning than in arousal or attention, and supporting the contention that an “LTP-like” process is a neural substrate for memory formation.

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