Biology and Philosophy 6 (2):135-154 (1991)

From the 1930s through the 1970s, C. H. Waddington attempted to reunite genetics, embryology, and evolution. One of the means to effect this synthesis was his model of the epigenetic landscape. This image originally recast genetic data in terms of embryological diagrams and was used to show the identity of genes and inducers and to suggest the similarities between embryological and genetic approaches to development. Later, the image became more complex and integrated gene activity and mutations. These revised epigenetic landscapes presented an image of how mutations could alter developmental pathways to yield larger phenotypic changes. These diagrams became less important as the operon became used to model differential gene regulation.
Keywords Epigenetic landscape  synthesis of evolution  genetics and development  Waddington
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DOI 10.1007/BF02426835
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References found in this work BETA

The Evolution of an Evolutionist.C. H. Waddington - 1977 - Journal of the History of Biology 10 (2):369-370.
The Embryological Origins of the Gene Theory.Scott F. Gilbert - 1978 - Journal of the History of Biology 11 (2):307-351.

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Citations of this work BETA

The Epigenetic Landscape in the Course of Time: Conrad Hal Waddington’s Methodological Impact on the Life Sciences.Jan Baedke - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):756-773.

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