Targeted Chemotherapy, the Medical Ecosystem, and the Future of American Health Care

Perspectives in Biology and Medicine 57 (2):268-284 (2014)
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Abstract

In light of the central role that medications play in medical progress, the declining rate of new drug development over the past decade is cause for concern . Without important breakthroughs in drug discovery, the future will not be auspicious for the many people suffering from chronic and incurable illnesses. The sluggish pace of pharmaceutical innovation has been particularly characteristic of the largest drug manufacturers, which have generally focused their energies on potential blockbuster medications, those that can generate over $1 billion in annual revenue . Given Pharma’s struggles, the success of the country’s largest drug manufacturer in bringing the ..

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